ID   A0A317W9Q7_ASPEC        Unreviewed;      1095 AA.
AC   A0A317W9Q7;
DT   10-OCT-2018, integrated into UniProtKB/TrEMBL.
DT   10-OCT-2018, sequence version 1.
DT   27-MAR-2024, entry version 21.
DE   SubName: Full=Importin beta-4 subunit {ECO:0000313|EMBL:PWY82481.1};
GN   ORFNames=BO83DRAFT_374961 {ECO:0000313|EMBL:PWY82481.1};
OS   Aspergillus eucalypticola (strain CBS 122712 / IBT 29274).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus.
OX   NCBI_TaxID=1448314 {ECO:0000313|EMBL:PWY82481.1, ECO:0000313|Proteomes:UP000246171};
RN   [1] {ECO:0000313|EMBL:PWY82481.1, ECO:0000313|Proteomes:UP000246171}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CBS 122712 {ECO:0000313|EMBL:PWY82481.1,
RC   ECO:0000313|Proteomes:UP000246171};
RG   DOE Joint Genome Institute;
RA   Vesth T.C., Nybo J., Theobald S., Brandl J., Frisvad J.C., Nielsen K.F.,
RA   Lyhne E.K., Kogle M.E., Kuo A., Riley R., Clum A., Nolan M., Lipzen A.,
RA   Salamov A., Henrissat B., Wiebenga A., De Vries R.P., Grigoriev I.V.,
RA   Mortensen U.H., Andersen M.R., Baker S.E.;
RT   "The genomes of Aspergillus section Nigri reveals drivers in fungal
RT   speciation.";
RL   Submitted (DEC-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PWY82481.1}.
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DR   EMBL; MSFU01000003; PWY82481.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A317W9Q7; -.
DR   VEuPathDB; FungiDB:BO83DRAFT_374961; -.
DR   OrthoDB; 22606at2759; -.
DR   Proteomes; UP000246171; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005634; C:nucleus; IEA:UniProt.
DR   GO; GO:0031267; F:small GTPase binding; IEA:InterPro.
DR   GO; GO:0006606; P:protein import into nucleus; IEA:InterPro.
DR   Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR   InterPro; IPR011989; ARM-like.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR021133; HEAT_type_2.
DR   InterPro; IPR001494; Importin-beta_N.
DR   InterPro; IPR040122; Importin_beta.
DR   InterPro; IPR034085; TOG.
DR   PANTHER; PTHR10527; IMPORTIN BETA; 1.
DR   PANTHER; PTHR10527:SF6; IMPORTIN-4; 1.
DR   Pfam; PF13513; HEAT_EZ; 1.
DR   Pfam; PF03810; IBN_N; 1.
DR   SMART; SM00913; IBN_N; 1.
DR   SMART; SM01349; TOG; 1.
DR   SUPFAM; SSF48371; ARM repeat; 2.
DR   PROSITE; PS50077; HEAT_REPEAT; 3.
DR   PROSITE; PS50166; IMPORTIN_B_NT; 1.
PE   4: Predicted;
KW   Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT   DOMAIN          24..91
FT                   /note="Importin N-terminal"
FT                   /evidence="ECO:0000259|PROSITE:PS50166"
FT   REPEAT          162..200
FT                   /note="HEAT"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00103"
FT   REPEAT          386..424
FT                   /note="HEAT"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00103"
FT   REPEAT          480..515
FT                   /note="HEAT"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00103"
FT   REGION          648..668
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        653..668
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1095 AA;  121544 MW;  900788B32A1AA631 CRC64;
     MDQQRFLQQL QIVLNPSQGN VKEATGVLQR EFYKSPESLV FLIQIATGHE DPNLRQLAAV
     ESRTLVVKHW VSVQASQKPQ IREQLLRAAV GESSSLVRHS VARVISAIAK IDLNDGEWAD
     LPNFLLQAAS TGNKEERAVS IYILLTILET LGDAFEEKFD ELFQLFSKTI SDPESEEVRM
     NTLMALSKLA MYLDSEESVA PVKAFQNLIP SMVAVLKDVI TREQDDGIMQ GFEVFQTLLG
     CDPALLTVHL KDLVIFMNEL AGNVEQEEDV RTQAISFLMQ CVQYRKLKIQ GMRIGEQLTR
     TALQVVTELG DASPADDDIT PARSALGLLD ILAQSLPPSQ VVVPLLQTLG QYFNNGNPDY
     RRAGIMALGM CVEGAPDFIS TQMQEIFPMV LQLLADPEPK VRQASLHAVA RLADDLAEDL
     SQEHERLMPL LFKNLASAMQ EYKGEEDGPT VDIMKAGISA IDAVVDGLDE KDVAPYQGEL
     VPILHNLFKH PDFRIKGLAA GALGSLASSA GDSFLPFFDD SMHLLQEFAT VKDSEEELDL
     RASVTDAMGE MAAAAGPERY QPYVEPLMRA TEEALHLGHS RLKESTYIFW GAMSKVYVEH
     FSPFLDGVVK GLFACIEQDE TDLDVSLGAA AKDLIGQEVT IGGRKVRVAD ADDDDDEPTG
     EDGDIEDVDV DDEDAWDDIT ATTPLSLEKE IAVEVIGDLV THTKSAYLPY FEKTIEMVLP
     LAEHPYEGVR KSTISTLHRS YAMLYCIAEE SGQMAKWQPG LPLQVQPAKE VQKFGEILMT
     ATVKMWTEED DRATVADINR NMAENLRYCG PSLISNETTL HNVITMITDI ITKKHPCQLE
     FGPEEETLEA GEETSEFDWV VVDTGLDVVS GMAAALGASF AELWKVFEKT VMRYAGSTEA
     LERATAVGVI AECINGMGSA VTPYTASFLK LLVHRLGDED TQTRSNAAYA VGRLVEHSDA
     KDQIVKEFPT ILSRLEQCLH MNVSRLQDNA TGCLSRMILR HRENVPIKDV LPVLLTILPL
     KNDYEENDPL YHMICQLYKW EDPTVRELTP QLVPIFQAVL SDEDQLEEER RAELVELVKW
     LNQMQPGAAP WADQL
//