ID A0A317WNA4_9EURO Unreviewed; 208 AA.
AC A0A317WNA4;
DT 10-OCT-2018, integrated into UniProtKB/TrEMBL.
DT 10-OCT-2018, sequence version 1.
DT 27-MAR-2024, entry version 14.
DE RecName: Full=Mediator of RNA polymerase II transcription subunit 9 {ECO:0000256|ARBA:ARBA00020636, ECO:0000256|RuleBase:RU364145};
DE AltName: Full=Mediator complex subunit 9 {ECO:0000256|ARBA:ARBA00031260, ECO:0000256|RuleBase:RU364145};
GN Name=MED9 {ECO:0000256|RuleBase:RU364145};
GN ORFNames=BO94DRAFT_58983 {ECO:0000313|EMBL:PWY87934.1};
OS Aspergillus sclerotioniger CBS 115572.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus.
OX NCBI_TaxID=1450535 {ECO:0000313|EMBL:PWY87934.1, ECO:0000313|Proteomes:UP000246702};
RN [1] {ECO:0000313|EMBL:PWY87934.1, ECO:0000313|Proteomes:UP000246702}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 115572 {ECO:0000313|EMBL:PWY87934.1,
RC ECO:0000313|Proteomes:UP000246702};
RG DOE Joint Genome Institute;
RA Vesth T.C., Nybo J., Theobald S., Brandl J., Frisvad J.C., Nielsen K.F.,
RA Lyhne E.K., Kogle M.E., Kuo A., Riley R., Clum A., Nolan M., Lipzen A.,
RA Salamov A., Henrissat B., Wiebenga A., De Vries R.P., Grigoriev I.V.,
RA Mortensen U.H., Andersen M.R., Baker S.E.;
RT "The genomes of Aspergillus section Nigri reveals drivers in fungal
RT speciation.";
RL Submitted (DEC-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Component of the Mediator complex, a coactivator involved in
CC the regulated transcription of nearly all RNA polymerase II-dependent
CC genes. Mediator functions as a bridge to convey information from gene-
CC specific regulatory proteins to the basal RNA polymerase II
CC transcription machinery. Mediator is recruited to promoters by direct
CC interactions with regulatory proteins and serves as a scaffold for the
CC assembly of a functional preinitiation complex with RNA polymerase II
CC and the general transcription factors. {ECO:0000256|RuleBase:RU364145}.
CC -!- SUBUNIT: Component of the Mediator complex.
CC {ECO:0000256|RuleBase:RU364145}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|RuleBase:RU364145}.
CC -!- SIMILARITY: Belongs to the Mediator complex subunit 9 family.
CC {ECO:0000256|ARBA:ARBA00008089, ECO:0000256|RuleBase:RU364145}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PWY87934.1}.
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DR EMBL; MSFK01000013; PWY87934.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A317WNA4; -.
DR STRING; 1450535.A0A317WNA4; -.
DR OrthoDB; 2149701at2759; -.
DR Proteomes; UP000246702; Unassembled WGS sequence.
DR GO; GO:0016592; C:mediator complex; IEA:InterPro.
DR GO; GO:0003712; F:transcription coregulator activity; IEA:InterPro.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IEA:InterPro.
DR InterPro; IPR011425; Med9.
DR Pfam; PF07544; Med9; 1.
PE 3: Inferred from homology;
KW Activator {ECO:0000256|RuleBase:RU364145};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|RuleBase:RU364145};
KW Reference proteome {ECO:0000313|Proteomes:UP000246702};
KW Transcription {ECO:0000256|ARBA:ARBA00023163,
KW ECO:0000256|RuleBase:RU364145};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015,
KW ECO:0000256|RuleBase:RU364145}.
FT REGION 1..35
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 56..97
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 160..194
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 75..97
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 208 AA; 21405 MW; DF98AA2025F8C1A9 CRC64;
MASRSATPLP KPSAAPETPM VKDAPAAPQV VPFPSPQTFD IVPPLHGLLL RLLSPPTNAA
GVSNGVRSAD DPNGAVAPTS ASGQSQSQPH SSAIAGAENN NNTVVLATVP SAGPGPVPAA
AEIAALGSNA PPPLEIKDLP TEASSIKIRI QKAYAVVDSL PDVDRSVADQ EEEIKELENR
IAKLNSVISD FGKRARPESA RKPKFQGP
//
