ID A0A317WQN1_9EURO Unreviewed; 932 AA.
AC A0A317WQN1;
DT 10-OCT-2018, integrated into UniProtKB/TrEMBL.
DT 10-OCT-2018, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE SubName: Full=Rho guanyl nucleotide exchange factor {ECO:0000313|EMBL:PWY87592.1};
GN ORFNames=BO70DRAFT_287815 {ECO:0000313|EMBL:PWY87592.1};
OS Aspergillus heteromorphus CBS 117.55.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus.
OX NCBI_TaxID=1448321 {ECO:0000313|EMBL:PWY87592.1, ECO:0000313|Proteomes:UP000247233};
RN [1] {ECO:0000313|EMBL:PWY87592.1, ECO:0000313|Proteomes:UP000247233}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 117.55 {ECO:0000313|EMBL:PWY87592.1,
RC ECO:0000313|Proteomes:UP000247233};
RG DOE Joint Genome Institute;
RA Vesth T.C., Nybo J., Theobald S., Brandl J., Frisvad J.C., Nielsen K.F.,
RA Lyhne E.K., Kogle M.E., Kuo A., Riley R., Clum A., Nolan M., Lipzen A.,
RA Salamov A., Henrissat B., Wiebenga A., De Vries R.P., Grigoriev I.V.,
RA Mortensen U.H., Andersen M.R., Baker S.E.;
RT "The genomes of Aspergillus section Nigri reveals drivers in fungal
RT speciation.";
RL Submitted (DEC-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PWY87592.1}.
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DR EMBL; MSFL01000006; PWY87592.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A317WQN1; -.
DR STRING; 1448321.A0A317WQN1; -.
DR VEuPathDB; FungiDB:BO70DRAFT_287815; -.
DR OrthoDB; 23973at2759; -.
DR Proteomes; UP000247233; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:InterPro.
DR CDD; cd05992; PB1; 1.
DR CDD; cd13246; PH_Scd1; 1.
DR CDD; cd00160; RhoGEF; 1.
DR Gene3D; 1.20.900.10; Dbl homology (DH) domain; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR010481; Cdc24/Scd1_N.
DR InterPro; IPR033511; Cdc24/Scd1_PH_dom.
DR InterPro; IPR035899; DBL_dom_sf.
DR InterPro; IPR000219; DH-domain.
DR InterPro; IPR000270; PB1_dom.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR001849; PH_domain.
DR PANTHER; PTHR47339; CELL DIVISION CONTROL PROTEIN 24; 1.
DR PANTHER; PTHR47339:SF1; CELL DIVISION CONTROL PROTEIN 24; 1.
DR Pfam; PF06395; CDC24; 1.
DR Pfam; PF00564; PB1; 1.
DR Pfam; PF15411; PH_10; 1.
DR Pfam; PF00621; RhoGEF; 1.
DR SMART; SM00233; PH; 1.
DR SMART; SM00325; RhoGEF; 1.
DR SUPFAM; SSF54277; CAD & PB1 domains; 1.
DR SUPFAM; SSF48065; DBL homology domain (DH-domain); 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR PROSITE; PS50010; DH_2; 1.
DR PROSITE; PS51745; PB1; 1.
PE 4: Predicted;
KW Glycosyltransferase {ECO:0000256|ARBA:ARBA00022676};
KW Reference proteome {ECO:0000313|Proteomes:UP000247233};
KW Transferase {ECO:0000256|ARBA:ARBA00022676}.
FT DOMAIN 178..357
FT /note="DH"
FT /evidence="ECO:0000259|PROSITE:PS50010"
FT DOMAIN 834..930
FT /note="PB1"
FT /evidence="ECO:0000259|PROSITE:PS51745"
FT REGION 566..726
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 759..828
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 566..581
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 608..666
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 675..690
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 759..792
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 932 AA; 104913 MW; 98352CE12F0F46ED CRC64;
MAETVIMSGA PIAEDNIINR RGGESMYQTC VNLKKRLAEV PNFEPHMREM EEADMAQGNT
DPVASLWNCL RTGYPLLTIY NASGPEEYLE IDTTKVAEAK RPKAATFKFL QASLQKLDFP
QQDCFLITDL YGENTTGFTK VIKMVNLVLD ILEMQGQLKR PSDDASRAPA QGTIKLTKRE
HILKELLETE RDYVHHLQNL QALKKELEET GALTGDASHQ IFLNLNNLLD FAQRFLIRIE
QHYALPEERQ NWGELFIQHE DAFPQYEPFI ANQMRCDEVC LRDWDKIHEA PRSKDLLQMV
AQPATLNGFF VKPFQRLTKY PLMLGELLKQ TENPDLRIDI QRAIDTIQSV LDSANDAIDK
EHLQTAVKDL AERVDDWKTL KIEAFGDLLR FGTFSVIKGD SAKDSEREYH IYLFERILLC
CKDINPNKQK SKLNLGKDKP ATTARGKARL QLKGRIYMAN VTDVLCMPKP GSYRIQIFWK
GDPNVVDNFI IRYQNESIMR KWANDIDAQR LIQTEQRNVR NTGTSETEFT YMKSVTNMPN
PYLENDEEQA ATKEAAFFSE FPMSRNASST SLRTRSATGG SGGSGPPPPL SVGRPPRFAV
PDPSLSVHTH FSGGSMSPAE RNAPSYFSPV ADTASTRSSS QSTGFSYTSS SRQTTPTNTW
NEENARYTAP ALSRATSRDG PNSNTFFSGA PGRAAQRPSL PPMSGPQAAN GIARMRSASS
PDIHAHNPEM RRYMGAHTMQ TVDNVPVPPI PAHMASMKAP VNRSQTNSPT NGNLPIPSAN
HLSNSQQHPD QRHMTPTHFH EPQYSDHRPG TSAGDQPTSP LSYEPDEEPL MPTQLKVKVN
FDDNYVTLVI ASNIMFRSLI DRVDAKLARF THRSIGSKSV RLRYRDEDGD FVTIDSDEAV
QLAFMEWREQ QRDMLARGQV GEIQLYCQAV ET
//
