ID A0A317WU27_9EURO Unreviewed; 517 AA.
AC A0A317WU27;
DT 10-OCT-2018, integrated into UniProtKB/TrEMBL.
DT 10-OCT-2018, sequence version 1.
DT 24-JAN-2024, entry version 14.
DE RecName: Full=methylmalonate-semialdehyde dehydrogenase (CoA acylating) {ECO:0000256|ARBA:ARBA00013048};
DE EC=1.2.1.27 {ECO:0000256|ARBA:ARBA00013048};
GN ORFNames=BO70DRAFT_377149 {ECO:0000313|EMBL:PWY89923.1};
OS Aspergillus heteromorphus CBS 117.55.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus.
OX NCBI_TaxID=1448321 {ECO:0000313|EMBL:PWY89923.1, ECO:0000313|Proteomes:UP000247233};
RN [1] {ECO:0000313|EMBL:PWY89923.1, ECO:0000313|Proteomes:UP000247233}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 117.55 {ECO:0000313|EMBL:PWY89923.1,
RC ECO:0000313|Proteomes:UP000247233};
RG DOE Joint Genome Institute;
RA Vesth T.C., Nybo J., Theobald S., Brandl J., Frisvad J.C., Nielsen K.F.,
RA Lyhne E.K., Kogle M.E., Kuo A., Riley R., Clum A., Nolan M., Lipzen A.,
RA Salamov A., Henrissat B., Wiebenga A., De Vries R.P., Grigoriev I.V.,
RA Mortensen U.H., Andersen M.R., Baker S.E.;
RT "The genomes of Aspergillus section Nigri reveals drivers in fungal
RT speciation.";
RL Submitted (DEC-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PWY89923.1}.
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DR EMBL; MSFL01000003; PWY89923.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A317WU27; -.
DR STRING; 1448321.A0A317WU27; -.
DR VEuPathDB; FungiDB:BO70DRAFT_377149; -.
DR OrthoDB; 275238at2759; -.
DR Proteomes; UP000247233; Unassembled WGS sequence.
DR GO; GO:0004491; F:methylmalonate-semialdehyde dehydrogenase (acylating, NAD) activity; IEA:UniProtKB-EC.
DR CDD; cd07085; ALDH_F6_MMSDH; 1.
DR InterPro; IPR016161; Ald_DH/histidinol_DH.
DR InterPro; IPR016163; Ald_DH_C.
DR InterPro; IPR016160; Ald_DH_CS_CYS.
DR InterPro; IPR016162; Ald_DH_N.
DR InterPro; IPR015590; Aldehyde_DH_dom.
DR InterPro; IPR010061; MeMal-semiAld_DH.
DR NCBIfam; TIGR01722; MMSDH; 1.
DR PANTHER; PTHR43866; MALONATE-SEMIALDEHYDE DEHYDROGENASE; 1.
DR PANTHER; PTHR43866:SF3; METHYLMALONATE-SEMIALDEHYDE DEHYDROGENASE [ACYLATING], MITOCHONDRIAL; 1.
DR Pfam; PF00171; Aldedh; 1.
DR SUPFAM; SSF53720; ALDH-like; 1.
DR PROSITE; PS00070; ALDEHYDE_DEHYDR_CYS; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000247233}.
FT DOMAIN 36..498
FT /note="Aldehyde dehydrogenase"
FT /evidence="ECO:0000259|Pfam:PF00171"
SQ SEQUENCE 517 AA; 55752 MW; AF8C5FC9FD8BEF0F CRC64;
MSSNTKFHTF TYEGNHTAPK SIRNVELFID NELVSSKASR WIDVHDPATN NIVCRVPEAT
PEELQAAVTS AKNAFPAWSS TSIMKRQNMM FKLTHLIQNN MDALAVSIVT EQGKTQADAK
GDVLRGLQVC ETACGITTQL PGEVLEVAKD METRSYQLPL GVVAAICPFN FPAMIPLWSL
PLAVITGNCM ILKPTERAPG AAMMIAELCK EAGFPPGVVN VIHGSKPAVD FILEAPEIKA
ISFVGSNKVG EYIYNRGTSL GKRVQANLGA KNHAVVLPDC AKNHALSAIA GAAFGAAGQR
CMALSVLLTV GSAREWIPDL VAKAKEYRAG SGFHERSDLG PLITPQSRDR CVDLIASAEA
EGATVVLDGR EYKPDGYPNG NWVGPTIITG VRKDMKCYRE EIFGPVLLCM ESDTINSAID
LVNSNDWGNG AVIFTQSGSS ATHFQKNIEA GQIGINVPIP VPLPMFSFTG NKRSVGGTGL
LNFYGKDGLR FYTQWKTVTS LWKSEDATEL SRPTAMV
//
