ID A0A317WZ62_9EURO Unreviewed; 402 AA.
AC A0A317WZ62;
DT 10-OCT-2018, integrated into UniProtKB/TrEMBL.
DT 10-OCT-2018, sequence version 1.
DT 27-MAR-2024, entry version 17.
DE SubName: Full=O-methyltransferase {ECO:0000313|EMBL:PWY91669.1};
GN ORFNames=BO94DRAFT_533129 {ECO:0000313|EMBL:PWY91669.1};
OS Aspergillus sclerotioniger CBS 115572.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus.
OX NCBI_TaxID=1450535 {ECO:0000313|EMBL:PWY91669.1, ECO:0000313|Proteomes:UP000246702};
RN [1] {ECO:0000313|EMBL:PWY91669.1, ECO:0000313|Proteomes:UP000246702}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 115572 {ECO:0000313|EMBL:PWY91669.1,
RC ECO:0000313|Proteomes:UP000246702};
RG DOE Joint Genome Institute;
RA Vesth T.C., Nybo J., Theobald S., Brandl J., Frisvad J.C., Nielsen K.F.,
RA Lyhne E.K., Kogle M.E., Kuo A., Riley R., Clum A., Nolan M., Lipzen A.,
RA Salamov A., Henrissat B., Wiebenga A., De Vries R.P., Grigoriev I.V.,
RA Mortensen U.H., Andersen M.R., Baker S.E.;
RT "The genomes of Aspergillus section Nigri reveals drivers in fungal
RT speciation.";
RL Submitted (DEC-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PWY91669.1}.
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DR EMBL; MSFK01000008; PWY91669.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A317WZ62; -.
DR OrthoDB; 1067404at2759; -.
DR Proteomes; UP000246702; Unassembled WGS sequence.
DR GO; GO:0008171; F:O-methyltransferase activity; IEA:InterPro.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR GO; GO:0044550; P:secondary metabolite biosynthetic process; IEA:UniProt.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR016461; COMT-like.
DR InterPro; IPR001077; O_MeTrfase_dom.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR43712:SF1; HYPOTHETICAL O-METHYLTRANSFERASE (EUROFUNG)-RELATED; 1.
DR PANTHER; PTHR43712; PUTATIVE (AFU_ORTHOLOGUE AFUA_4G14580)-RELATED; 1.
DR Pfam; PF00891; Methyltransf_2; 1.
DR PIRSF; PIRSF005739; O-mtase; 2.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS51683; SAM_OMT_II; 1.
PE 4: Predicted;
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603,
KW ECO:0000313|EMBL:PWY91669.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000246702};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW Transferase {ECO:0000313|EMBL:PWY91669.1}.
FT DOMAIN 179..381
FT /note="O-methyltransferase"
FT /evidence="ECO:0000259|Pfam:PF00891"
FT ACT_SITE 311
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR005739-1"
SQ SEQUENCE 402 AA; 44430 MW; EFB0F66C4EE5F2E7 CRC64;
MATAQPNLDH IQQCLAEVTA AVDQYRAAAS SHTGQDARYQ LTVQATRLVR AIRGPADLVF
ANFENMVKMG AIRTLLEAGV FDAIPTGGQS ISAAEITAKT GVDKEIIVRL MRALTPVGPF
RETGEEQYAH TPESEVLLAP QMRAVFGLMI DEYSPAMLRT HEFLQQQQWQ HRIGLRSNPY
TLVHGCDGQT MFEHISQRPA RATRLNDAMV AEDSLLAEIG LYPFVKTLGP LAQPDGVTVV
DVGGGRGHIL RQLKENMPSL PGRFILQDRD MVIADNGSDM EAHGIEPMAH DFFEPQPVKG
ALVYFVRRVL HDWPDEEVRQ ILAHLAAAMD REKSRILITE TIIPEVGATT TNAYMDLTMM
TFGGRERTVK DFAHLFDLAG LKLANVYQAP GVPMVVVEAH LK
//
