ID A0A317XEP8_9EURO Unreviewed; 399 AA.
AC A0A317XEP8;
DT 10-OCT-2018, integrated into UniProtKB/TrEMBL.
DT 10-OCT-2018, sequence version 1.
DT 27-MAR-2024, entry version 16.
DE SubName: Full=O-methyltransferase {ECO:0000313|EMBL:PWY95090.1};
GN ORFNames=BO94DRAFT_508040 {ECO:0000313|EMBL:PWY95090.1};
OS Aspergillus sclerotioniger CBS 115572.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus.
OX NCBI_TaxID=1450535 {ECO:0000313|EMBL:PWY95090.1, ECO:0000313|Proteomes:UP000246702};
RN [1] {ECO:0000313|EMBL:PWY95090.1, ECO:0000313|Proteomes:UP000246702}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 115572 {ECO:0000313|EMBL:PWY95090.1,
RC ECO:0000313|Proteomes:UP000246702};
RG DOE Joint Genome Institute;
RA Vesth T.C., Nybo J., Theobald S., Brandl J., Frisvad J.C., Nielsen K.F.,
RA Lyhne E.K., Kogle M.E., Kuo A., Riley R., Clum A., Nolan M., Lipzen A.,
RA Salamov A., Henrissat B., Wiebenga A., De Vries R.P., Grigoriev I.V.,
RA Mortensen U.H., Andersen M.R., Baker S.E.;
RT "The genomes of Aspergillus section Nigri reveals drivers in fungal
RT speciation.";
RL Submitted (DEC-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PWY95090.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; MSFK01000003; PWY95090.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A317XEP8; -.
DR OrthoDB; 1067404at2759; -.
DR Proteomes; UP000246702; Unassembled WGS sequence.
DR GO; GO:0008171; F:O-methyltransferase activity; IEA:InterPro.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR GO; GO:0044550; P:secondary metabolite biosynthetic process; IEA:UniProt.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR016461; COMT-like.
DR InterPro; IPR001077; O_MeTrfase_dom.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR43712:SF1; HYPOTHETICAL O-METHYLTRANSFERASE (EUROFUNG)-RELATED; 1.
DR PANTHER; PTHR43712; PUTATIVE (AFU_ORTHOLOGUE AFUA_4G14580)-RELATED; 1.
DR Pfam; PF00891; Methyltransf_2; 1.
DR PIRSF; PIRSF005739; O-mtase; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS51683; SAM_OMT_II; 1.
PE 4: Predicted;
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603,
KW ECO:0000313|EMBL:PWY95090.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000246702};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW Transferase {ECO:0000313|EMBL:PWY95090.1}.
FT DOMAIN 233..377
FT /note="O-methyltransferase"
FT /evidence="ECO:0000259|Pfam:PF00891"
FT ACT_SITE 307
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR005739-1"
SQ SEQUENCE 399 AA; 44627 MW; F2B8F3882E49AC44 CRC64;
MGDTGHKVEA VQQSLDQLIS AAKKSQENLS VEDRYSLMIK ATRLVQTLRG PADALFAHLE
NAVHMGAIRT LLEAGVFHAI PTGGKSISAA EISEKTGVDK ELIVRYMRAV TPIGPFQETG
EEQYAHTPFS EIYLAPQMRA VYNLTVDEYA PPMFQSHEFF RQKNWKHEIS PRSNQYTFAH
DCEGKTMFEH VAQFPDRLSR LSDAMTASDS NLPTVGIYPI AEELGPLASD DTVTLVDVGG
GRGHVIRQIK ESAPDLKGRF ILQDEAHVIQ NNGDENEKYG IEAMAHDFFQ PQPVKGALAY
YLRRCLHDWP NEPEAQKILS NLAAAMDREK SRVLITECVV PEVGATMFHA WMDQAVMTIG
GRERTEKDWA HLLDISGLRL VKVWRTPEMS VGVVEARLK
//
