ID A0A317XPD3_9BASI Unreviewed; 1082 AA.
AC A0A317XPD3;
DT 10-OCT-2018, integrated into UniProtKB/TrEMBL.
DT 10-OCT-2018, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE RecName: Full=DNA 3'-5' helicase {ECO:0000256|ARBA:ARBA00034808};
DE EC=5.6.2.4 {ECO:0000256|ARBA:ARBA00034808};
GN ORFNames=BCV70DRAFT_162107 {ECO:0000313|EMBL:PWY99727.1};
OS Testicularia cyperi.
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Ustilaginomycotina;
OC Ustilaginomycetes; Ustilaginales; Anthracoideaceae; Testicularia.
OX NCBI_TaxID=1882483 {ECO:0000313|EMBL:PWY99727.1, ECO:0000313|Proteomes:UP000246740};
RN [1] {ECO:0000313|EMBL:PWY99727.1, ECO:0000313|Proteomes:UP000246740}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MCA 3645 {ECO:0000313|EMBL:PWY99727.1,
RC ECO:0000313|Proteomes:UP000246740};
RX PubMed=29771364; DOI=10.1093/molbev/msy072;
RA Kijpornyongpan T., Mondo S.J., Barry K., Sandor L., Lee J., Lipzen A.,
RA Pangilinan J., LaButti K., Hainaut M., Henrissat B., Grigoriev I.V.,
RA Spatafora J.W., Aime M.C.;
RT "Broad genomic sampling reveals a smut pathogenic ancestry of the fungal
RT clade Ustilaginomycotina.";
RL Mol. Biol. Evol. 0:0-0(2018).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=5.6.2.4;
CC Evidence={ECO:0000256|ARBA:ARBA00034618};
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DR EMBL; KZ819194; PWY99727.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A317XPD3; -.
DR STRING; 1882483.A0A317XPD3; -.
DR InParanoid; A0A317XPD3; -.
DR Proteomes; UP000246740; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003678; F:DNA helicase activity; IEA:InterPro.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-UniRule.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR014017; DNA_helicase_UvrD-like_C.
DR InterPro; IPR000212; DNA_helicase_UvrD/REP.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR014016; UvrD-like_ATP-bd.
DR PANTHER; PTHR11070:SF30; F-BOX DNA HELICASE 1; 1.
DR PANTHER; PTHR11070; UVRD / RECB / PCRA DNA HELICASE FAMILY MEMBER; 1.
DR Pfam; PF00580; UvrD-helicase; 1.
DR Pfam; PF13361; UvrD_C; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51198; UVRD_HELICASE_ATP_BIND; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00560};
KW Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000256|PROSITE-
KW ProRule:PRU00560};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|PROSITE-
KW ProRule:PRU00560};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00560}; Reference proteome {ECO:0000313|Proteomes:UP000246740}.
FT DOMAIN 333..618
FT /note="UvrD-like helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51198"
FT REGION 1..55
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 160..198
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 666..698
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 964..983
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 11..55
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 167..181
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 354..361
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00560"
SQ SEQUENCE 1082 AA; 120312 MW; 5CE9EA5A37F53A0D CRC64;
MIPTPAVAVA STSAAAFTTP SRPAKRTDPP ASSSSSFVAH SRSIKKKVNS TNDDSLAARL
QPKLTSSSWR RTKSYQHVDL SGPTRRTVLE WLPREVVFMV IGLLGFPDIQ NLLRADRRIR
AFVHSKTFAP WRKRLACFQH KERLYDDAIA LGEDAMFEAG AGDDHDLPSS SPDEHLDHQQ
HQQNTKNGNG TGRDQGRRDM EQAETAFLTE YTDVLRSLQL RTAPLDLTEL LPCVTRVWHE
HRSFAVLRKW CRDFALCKAD AMALLSLVDD STAIEFLAFV RLYLATVRIS RAFGSLLPPL
QVVRCLDYDC RCATLAFFAP ARVTSGDVPF RLTEEQTRFV HCDVRPGELV KVQAFAGTGK
TRSLLAYAER RPQKRFLYIA FNVSAANSAR ARFPSNVDCR TMHSVALRQV VLNAGQEIGD
LRARDVIKLL GERLPEGQML RAQSMATQTG RDPKLTPTAV ATYVLATLQR YFYSDDAHIT
PDKHVPSKVA IDTDLKVRSV ARCAQDLWDL IRSGVDERTN KPVRCPHDGY VKLLQLQAPH
HSENFFKAFD VLLLDEAQDL SAAQVSILLR AKKHCGILVV GDVFQKIYGF RGGTARAFNE
RLYPSTASFQ LTKSFRFGDA VARIATEMLA LRKPAAWEKP TRKPMLSGAS GSSDRVYAEA
RAILPRNSTS QGDPDHDAAE EQDQAAADAA PASTQAAVGE EGRRAIAIEA GSVLNIGRSE
EILAHTRIFR SNRKLCLTAL ALSATLPEPH KMFLKTSQSL QPEAIVTLLR DAHILYHNDS
RSMSRNSLLR DFASWKDLVQ RVEAEGGGES RLSLAVALGS LFASSDFLDQ VARLETRFSR
SESEATVVLT TVHQAKGLEW DRVVVEDDFR PVFGAGPSKR LEVAGLWHQD ELNHLYVGLT
RAKKQLIVSR PVLQWIAAIR GLYQYRLSSK PELCYQCQSS KNVVVVKELR IEAFDFLDPR
CNESVSDRTT TGSTRDNPVS FASDASSSTC NRASIHSDAI GDPDLVTFVL SAPKIAKQRP
KDDNATNLKA KAKITANPTF TATSNTKVKV DLSKHAFLST DHRAMKWAMM HHEYSQAVHS
WL
//
