ID A0A317XTI1_9BASI Unreviewed; 719 AA.
AC A0A317XTI1;
DT 10-OCT-2018, integrated into UniProtKB/TrEMBL.
DT 10-OCT-2018, sequence version 1.
DT 24-JAN-2024, entry version 22.
DE RecName: Full=Terpene cyclase/mutase family member {ECO:0000256|RuleBase:RU362003};
DE EC=5.4.99.- {ECO:0000256|RuleBase:RU362003};
GN ORFNames=BCV70DRAFT_199081 {ECO:0000313|EMBL:PWZ01644.1};
OS Testicularia cyperi.
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Ustilaginomycotina;
OC Ustilaginomycetes; Ustilaginales; Anthracoideaceae; Testicularia.
OX NCBI_TaxID=1882483 {ECO:0000313|EMBL:PWZ01644.1, ECO:0000313|Proteomes:UP000246740};
RN [1] {ECO:0000313|EMBL:PWZ01644.1, ECO:0000313|Proteomes:UP000246740}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MCA 3645 {ECO:0000313|EMBL:PWZ01644.1,
RC ECO:0000313|Proteomes:UP000246740};
RX PubMed=29771364; DOI=10.1093/molbev/msy072;
RA Kijpornyongpan T., Mondo S.J., Barry K., Sandor L., Lee J., Lipzen A.,
RA Pangilinan J., LaButti K., Hainaut M., Henrissat B., Grigoriev I.V.,
RA Spatafora J.W., Aime M.C.;
RT "Broad genomic sampling reveals a smut pathogenic ancestry of the fungal
RT clade Ustilaginomycotina.";
RL Mol. Biol. Evol. 0:0-0(2018).
CC -!- SIMILARITY: Belongs to the terpene cyclase/mutase family.
CC {ECO:0000256|ARBA:ARBA00009755, ECO:0000256|RuleBase:RU362003}.
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DR EMBL; KZ819190; PWZ01644.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A317XTI1; -.
DR STRING; 1882483.A0A317XTI1; -.
DR InParanoid; A0A317XTI1; -.
DR Proteomes; UP000246740; Unassembled WGS sequence.
DR GO; GO:0005811; C:lipid droplet; IEA:InterPro.
DR GO; GO:0016866; F:intramolecular transferase activity; IEA:InterPro.
DR GO; GO:0016104; P:triterpenoid biosynthetic process; IEA:InterPro.
DR CDD; cd02892; SQCY_1; 1.
DR Gene3D; 1.50.10.20; -; 2.
DR Gene3D; 6.20.120.20; -; 1.
DR InterPro; IPR032696; SQ_cyclase_C.
DR InterPro; IPR032697; SQ_cyclase_N.
DR InterPro; IPR018333; Squalene_cyclase.
DR InterPro; IPR002365; Terpene_synthase_CS.
DR InterPro; IPR008930; Terpenoid_cyclase/PrenylTrfase.
DR NCBIfam; TIGR01787; squalene_cyclas; 1.
DR PANTHER; PTHR11764:SF20; LANOSTEROL SYNTHASE; 1.
DR PANTHER; PTHR11764; TERPENE CYCLASE/MUTASE FAMILY MEMBER; 1.
DR Pfam; PF13243; SQHop_cyclase_C; 1.
DR Pfam; PF13249; SQHop_cyclase_N; 1.
DR SFLD; SFLDG01016; Prenyltransferase_Like_2; 1.
DR SUPFAM; SSF48239; Terpenoid cyclases/Protein prenyltransferases; 2.
DR PROSITE; PS01074; TERPENE_SYNTHASES; 1.
PE 3: Inferred from homology;
KW Isomerase {ECO:0000256|ARBA:ARBA00023235, ECO:0000256|RuleBase:RU362003};
KW Reference proteome {ECO:0000313|Proteomes:UP000246740};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 80..366
FT /note="Squalene cyclase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF13249"
FT DOMAIN 380..711
FT /note="Squalene cyclase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13243"
SQ SEQUENCE 719 AA; 81703 MW; 052D9B4495C587A3 CRC64;
MAPSSSSSPP LGATDPARWR LKVSDGGRHL WHYLRDDAQC DAWPQTVEDK YWLGLETDLP
DLPKANTPIQ SASNGLAFYR HLQSNDGHWA GEYGGPMFLL PGLIIGMYVT KTPIPQEWKV
EIARYLWHRA DKSDGGWGIH IEGCSTVFGT ALNYVVLRLV GVDPDHPMMV KARATLHKLG
GATGIPSWGK LWLAILNVYE WEGMNPIPPE LWLLPDWLPI HPWRWWIHTR MVYLPMGYLW
GKRFKAEMDP LIASLRDELY VEPYDSINWP KQANNIAQVD IYAPHTRTLE ALMAVVGTYD
KCHIPPIRKA GIKRAYDLIV MEDENTGYQC LGPVNKMLNY ITRWDVEGHD SHAMKMHREK
LKDFAWMGAE GLMMTGTNGS QLWDTSFIAQ AMVDSGLAQS EENKALTQHI LDWLDQCQIQ
NNPKHFQSNY RFATKGAWPF STKEQSYVVS DCTGEGLKAV IMLQQGVKSL TPKISPERMH
DSIDLMLSMQ NSNGGFASYE TINGPSILEW LNPAEVFGDI MIEYAYPECT TSVVTALLKF
RKIDTYRRQD IDNCVSKAVR YILAQQRPDG SWFGSWAICF TYATMFAVES LSLAGHTYEN
SDALKRACDF LISKQMDDGG WGETYKSCET GEYSHASKSQ VVQTAWVVIT LLHAKYPQHD
RIKRAVRVIM DRQLPNGSWA QEQIEGIFNR NCAISYPNYK FSFTIWALGK AARELDWST
//
