ID A0A318EG93_9GAMM Unreviewed; 702 AA.
AC A0A318EG93;
DT 10-OCT-2018, integrated into UniProtKB/TrEMBL.
DT 10-OCT-2018, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE RecName: Full=ATP-dependent DNA helicase RecG {ECO:0000256|ARBA:ARBA00017846, ECO:0000256|RuleBase:RU363016};
DE EC=3.6.4.12 {ECO:0000256|ARBA:ARBA00012551, ECO:0000256|RuleBase:RU363016};
GN Name=recG {ECO:0000256|RuleBase:RU363016};
GN ORFNames=C8D93_103401 {ECO:0000313|EMBL:PXV69825.1};
OS Sinimarinibacterium flocculans.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Nevskiales; Nevskiaceae;
OC Sinimarinibacterium.
OX NCBI_TaxID=985250 {ECO:0000313|EMBL:PXV69825.1, ECO:0000313|Proteomes:UP000248330};
RN [1] {ECO:0000313|EMBL:PXV69825.1, ECO:0000313|Proteomes:UP000248330}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 104150 {ECO:0000313|EMBL:PXV69825.1,
RC ECO:0000313|Proteomes:UP000248330};
RA Goeker M.;
RT "Genomic Encyclopedia of Type Strains, Phase IV (KMG-IV): sequencing the
RT most valuable type-strain genomes for metagenomic binning, comparative
RT biology and taxonomic classification.";
RL Submitted (APR-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Critical role in recombination and DNA repair. Helps process
CC Holliday junction intermediates to mature products by catalyzing branch
CC migration. Has a DNA unwinding activity characteristic of a DNA
CC helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-
CC DNA). {ECO:0000256|RuleBase:RU363016}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.12;
CC Evidence={ECO:0000256|RuleBase:RU363016};
CC -!- SIMILARITY: Belongs to the helicase family. RecG subfamily.
CC {ECO:0000256|ARBA:ARBA00007504, ECO:0000256|RuleBase:RU363016}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PXV69825.1}.
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DR EMBL; QICN01000003; PXV69825.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A318EG93; -.
DR OrthoDB; 9804325at2; -.
DR Proteomes; UP000248330; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:RHEA.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003678; F:DNA helicase activity; IEA:InterPro.
DR GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-UniRule.
DR GO; GO:0006281; P:DNA repair; IEA:UniProtKB-UniRule.
DR CDD; cd17992; DEXHc_RecG; 1.
DR CDD; cd04488; RecG_wedge_OBF; 1.
DR Gene3D; 2.40.50.140; Nucleic acid-binding proteins; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR004609; ATP-dep_DNA_helicase_RecG.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR012340; NA-bd_OB-fold.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR047112; RecG/Mfd.
DR InterPro; IPR045562; RecG_dom3_C.
DR InterPro; IPR033454; RecG_wedge.
DR NCBIfam; TIGR00643; recG; 1.
DR PANTHER; PTHR47964; ATP-DEPENDENT DNA HELICASE HOMOLOG RECG, CHLOROPLASTIC; 1.
DR PANTHER; PTHR47964:SF1; ATP-DEPENDENT DNA HELICASE HOMOLOG RECG, CHLOROPLASTIC; 1.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF19833; RecG_dom3_C; 1.
DR Pfam; PF17191; RecG_wedge; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF50249; Nucleic acid-binding proteins; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|RuleBase:RU363016};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW DNA damage {ECO:0000256|RuleBase:RU363016};
KW DNA recombination {ECO:0000256|RuleBase:RU363016};
KW DNA repair {ECO:0000256|RuleBase:RU363016};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000256|RuleBase:RU363016};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU363016};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW ECO:0000256|RuleBase:RU363016};
KW Reference proteome {ECO:0000313|Proteomes:UP000248330}.
FT DOMAIN 295..458
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 491..637
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT COILED 503..530
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 702 AA; 76357 MW; 35EF1A1FA5F7DCA5 CRC64;
MFRSARSKLG NGKAARSPLN LDSEITYLKG AGPAVAQRLR TLDLRCVRDL LFHLPTRYED
RRKHTPCARL RPDTDALVRG RIVAADVRFA GRRTLRVVID DGTGGLLLRF FHFNPAQRES
LAVGRWLQAY GSVRTGTAGP EMVHPQYRVA DEAEALQPDP YLAPIYPLTT GITQQRLRGL
IALALDLAAA DAALATTLPG LDGPATLDAL RAIHHPKSDA DAEALIERSH PAQTRLIHEE
LLAHQLGMRL LRGRLKARPA PAIRKPADAV SALLGVLPFA PTGAQRRVLD EVAKDLSASR
PMLRLVQGDV GSGKTVIAAA ALLAACRDGL QAVLVAPTEL LAEQHLRTLS AWFEPLGIAP
LFLSNRVKKA ERSRVLERLA APEPAIAVGT HALLQDGVDY ARLALTVVDE QHRFGVQQRI
ALREKGGKLA PHQLIMSATP IPRTLAQTLY ADLDVSVIDE LPPGRTPVTT VALSAAKRAE
IVARIGSACA EGRQAYWVCT LIEESEELDA EAAEATAARL REELPQLQVG LVHGRMKPDQ
KEVQMRAFKD GTTQLLVATT VIEVGVDVPN ASIMVIDNAE RLGLSQLHQL RGRVGRGARE
SQCVLLYQPP LSDMARARLE TLRATTDGFA IAQRDLELRG PGELLGRRQT GDIGMKLADP
VRDAPLVPPL QPLADRLLAE HPPLARLLIA RWVGDPERYA MV
//
