ID A0A318H6E5_9BURK Unreviewed; 1935 AA.
AC A0A318H6E5;
DT 10-OCT-2018, integrated into UniProtKB/TrEMBL.
DT 10-OCT-2018, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE RecName: Full=UvrABC system protein A {ECO:0000256|ARBA:ARBA00039316};
DE AltName: Full=Excinuclease ABC subunit A {ECO:0000256|ARBA:ARBA00042156};
GN ORFNames=C7444_101387 {ECO:0000313|EMBL:PXW99557.1};
OS Sphaerotilus hippei.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Sphaerotilaceae; Sphaerotilus.
OX NCBI_TaxID=744406 {ECO:0000313|EMBL:PXW99557.1, ECO:0000313|Proteomes:UP000247811};
RN [1] {ECO:0000313|EMBL:PXW99557.1, ECO:0000313|Proteomes:UP000247811}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 566 {ECO:0000313|EMBL:PXW99557.1,
RC ECO:0000313|Proteomes:UP000247811};
RA Goeker M.;
RT "Genomic Encyclopedia of Type Strains, Phase IV (KMG-IV): sequencing the
RT most valuable type-strain genomes for metagenomic binning, comparative
RT biology and taxonomic classification.";
RL Submitted (MAY-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- SIMILARITY: Belongs to the ABC transporter superfamily. UvrA family.
CC {ECO:0000256|ARBA:ARBA00038000}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PXW99557.1}.
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DR EMBL; QJJS01000001; PXW99557.1; -; Genomic_DNA.
DR OrthoDB; 9809851at2; -.
DR Proteomes; UP000247811; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0009380; C:excinuclease repair complex; IEA:InterPro.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0004518; F:nuclease activity; IEA:UniProtKB-KW.
DR GO; GO:0006289; P:nucleotide-excision repair; IEA:InterPro.
DR GO; GO:0009432; P:SOS response; IEA:UniProtKB-KW.
DR Gene3D; 3.30.190.20; -; 1.
DR Gene3D; 1.10.8.280; ABC transporter ATPase domain-like; 1.
DR Gene3D; 1.20.1580.10; ABC transporter ATPase like domain; 3.
DR Gene3D; 3.30.1490.20; ATP-grasp fold, A domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 5.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR017871; ABC_transporter-like_CS.
DR InterPro; IPR013815; ATP_grasp_subdomain_1.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR004602; UvrA.
DR InterPro; IPR041552; UvrA_DNA-bd.
DR InterPro; IPR041102; UvrA_inter.
DR NCBIfam; TIGR00630; uvra; 1.
DR PANTHER; PTHR43152; UVRABC SYSTEM PROTEIN A; 1.
DR PANTHER; PTHR43152:SF3; UVRABC SYSTEM PROTEIN A; 1.
DR Pfam; PF17755; UvrA_DNA-bind; 1.
DR Pfam; PF17760; UvrA_inter; 2.
DR SMART; SM00382; AAA; 4.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 4.
DR PROSITE; PS00211; ABC_TRANSPORTER_1; 3.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW DNA excision {ECO:0000256|ARBA:ARBA00022769};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Excision nuclease {ECO:0000256|ARBA:ARBA00022881};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000247811};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW SOS response {ECO:0000256|ARBA:ARBA00023236};
KW Translocase {ECO:0000256|ARBA:ARBA00022967};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT DOMAIN 1009..1560
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
SQ SEQUENCE 1935 AA; 210404 MW; 3F55E7C828D98AF3 CRC64;
MTAKKGSPAA GVIAATAHEA STGQGLIRIR GARQHNLKNL DLDIRTGELT VVTGPSGSGK
SSLVFDTLYA EGQRRYVETF SAYARQFLDR MDRPAVDAVE GVPPAIAIDQ TNPVRTSRST
VGTMTELNDH LKLLFARAAQ LFDRDTAGPV REDDPQSIRA DLQARCAAAG DPRLVVTFPV
ELPASTTPEE IEQWLSASGY TRVQAEREVA TLTGPRKVLD VVADRFRLGN AESIRVIEAL
EAALKRGSGR CNVYALGVDE GRDAIWRYSQ GLHCPESEQR YSAAQPAMFS FNSAFGACET
CRGFGRVIGV DFGLVIPDHR KTLRGGAIKP LQTPAWKECQ DDLIRYAGDA GIPRDTAWAQ
MSPAQQAWVI DGSPNWNGEW NQQWYGIRRF FEYLESKAYK MHIRVLLSKY RSYTPCGACG
GARLKTESLL WRLGGKPQAD AALPAAQRFL PVGVKWSRAQ LEALPGLSLH DLMLLPIDRM
RRFFDGLELP SQLLDDALNL LQGEIRTRLK YLCDVGLGYL SLDRQSRTLS GGEVQRINLT
TALGTSLVNT LFVLDEPSIG LHPRDMNRIN EAMLRLRDAG NTLVVVEHDP AVMLAADRVI
DLGPGPGTQG GRIVFDGTPE DLKAAETLTG AYLGARRTIG LGLTRPVVDS TPRLILEGAR
EHNLRNVTVE FPLQRLVCVT GVSGSGKSTL IQDVLHPALA RHFGQATESP GAHDRLLGAD
GLSDAVFVDQ SPIGKTARSN PASYVGAFDT MRELFAALPA AQQRSYTAGM FSFNAGDGRC
PTCGGSGFEH VEMQFLSDVY LRCPDCDGTR YRAELREVKI ERLGKAMSIS DVLELTVADA
VRLFADDREV VRALQPLADV GLDYVKLGQP VPTLSGGEAQ RLKLAGFLAE AAKAATSSKQ
KLAKKGTLFL FDEPTTGLHF DDIAKLMRAF RKLLEAGHSL LVIEHNLDVV RASDWIVDLG
PEGGEGGGEL VAEGTPADLK AHPTSHTGRS LREYDLSLGH GGQRVEEGVP LQTLVKARRD
RIRQAHDDAI QIVNAREHNL KGLSVDIPRG RFSVITGVSG SGKSTLAFDI LFNEGQRRYL
ESLNAYARSI VQPAGRPEVD AVYGIPPTVA IEQRLSRGGR KSTVATTTEV WHFLRLLYVK
LGTQYCPACS DFHAPADDWV AVQPQTPESI AAQLLRDHRG QHIGLLAPLV MNRKGIYTDL
AKWAKGKGHT HLRVDGEFLP TDKWPKLDRY KEHTIELPVA ELLVDVANEA LLRTRLAEAL
EHGKGVLHLL TPLKAAQSAK SLAASLEAGF LSTAFRSKAK VFSIKRACPQ CGTSYPELDP
RMFSYNSKHG WCPDCVGTGL TLTREQRKAL DDSVQEDKEK GREKTFAEPE VEDLVDTACG
TCSGARLNPV SRAVRFRDTS IAEVAARSVD EGRRWIEAHK LDGREAAIAR DVVTEIRNRL
SFLGDVGLGY LTLDRAAPTL SGGEAQRIRL AAQLGSNLQG VCYVLDEPTI GLHPRDNRIL
LDALHRLGRA GNTLVVVEHD EDTIRRADHI IDIGPGAGKR GGQVIAQGTA VELMANAASI
TGRFLNAPLK HPLQPRRPVD AQTPGLTLRG ASLHNLREVD VEVPLARLVA VTGVSGSGKS
TLARDVLLAN VQAVVSHKLA GRNAGPRPAW VGCTGLEGWS NVDRVLEVDQ TPIGKTPRSC
PATYIGFWDT IRKLFTETLE ARARGYAANR FSFNTGDGRC PGCEGQGLRT IEMAFLPDVK
VPCDLCHGAR FNQETLAVTW RGRSIGDVLQ MEVDEAVDFF ASMPSIAHPL QLLKDVGLGY
LTLGQPSPTL SGGEAQRIKL VTELSKVRDD VTRRGQKAPH TLYVLDEPTV GLHMADVEKL
IRVLHRLVNA GHSVVVIEHD LDVIAEADWV IDLGPDGGSG GGQVVVCGTP EQVVKSRSHT
GVALKPVLKR GAPKA
//
