ID A0A318JN95_9NOCA Unreviewed; 1067 AA.
AC A0A318JN95;
DT 10-OCT-2018, integrated into UniProtKB/TrEMBL.
DT 10-OCT-2018, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=DNA-binding SARP family transcriptional activator {ECO:0000313|EMBL:PXX56321.1};
GN ORFNames=DFR70_12062 {ECO:0000313|EMBL:PXX56321.1};
OS Nocardia tenerifensis.
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Nocardiaceae;
OC Nocardia.
OX NCBI_TaxID=228006 {ECO:0000313|EMBL:PXX56321.1, ECO:0000313|Proteomes:UP000247569};
RN [1] {ECO:0000313|EMBL:PXX56321.1, ECO:0000313|Proteomes:UP000247569}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 44704 {ECO:0000313|EMBL:PXX56321.1,
RC ECO:0000313|Proteomes:UP000247569};
RA Goeker M.;
RT "Genomic Encyclopedia of Type Strains, Phase IV (KMG-IV): sequencing the
RT most valuable type-strain genomes for metagenomic binning, comparative
RT biology and taxonomic classification.";
RL Submitted (MAY-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the AfsR/DnrI/RedD regulatory family.
CC {ECO:0000256|ARBA:ARBA00005820}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PXX56321.1}.
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DR EMBL; QJKF01000020; PXX56321.1; -; Genomic_DNA.
DR RefSeq; WP_051187690.1; NZ_QJKF01000020.1.
DR AlphaFoldDB; A0A318JN95; -.
DR OrthoDB; 3362145at2; -.
DR Proteomes; UP000247569; Unassembled WGS sequence.
DR GO; GO:0043531; F:ADP binding; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0000160; P:phosphorelay signal transduction system; IEA:InterPro.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd15831; BTAD; 1.
DR CDD; cd00093; HTH_XRE; 1.
DR Gene3D; 1.10.260.40; lambda repressor-like DNA-binding domains; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 3.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 2.
DR InterPro; IPR005158; BTAD.
DR InterPro; IPR001387; Cro/C1-type_HTH.
DR InterPro; IPR010982; Lambda_DNA-bd_dom_sf.
DR InterPro; IPR002182; NB-ARC.
DR InterPro; IPR001867; OmpR/PhoB-type_DNA-bd.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR016032; Sig_transdc_resp-reg_C-effctor.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR019734; TPR_repeat.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR PANTHER; PTHR47691:SF3; HTH-TYPE TRANSCRIPTIONAL REGULATOR RV0890C-RELATED; 1.
DR PANTHER; PTHR47691; REGULATOR-RELATED; 1.
DR Pfam; PF03704; BTAD; 1.
DR Pfam; PF13560; HTH_31; 1.
DR Pfam; PF00931; NB-ARC; 1.
DR Pfam; PF13424; TPR_12; 1.
DR Pfam; PF13176; TPR_7; 1.
DR Pfam; PF00486; Trans_reg_C; 1.
DR PRINTS; PR00364; DISEASERSIST.
DR SMART; SM01043; BTAD; 1.
DR SMART; SM00530; HTH_XRE; 1.
DR SMART; SM00028; TPR; 6.
DR SMART; SM00862; Trans_reg_C; 1.
DR SUPFAM; SSF46894; C-terminal effector domain of the bipartite response regulators; 1.
DR SUPFAM; SSF47413; lambda repressor-like DNA-binding domains; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF48452; TPR-like; 3.
DR PROSITE; PS50943; HTH_CROC1; 1.
DR PROSITE; PS51755; OMPR_PHOB; 1.
DR PROSITE; PS50005; TPR; 2.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW ProRule:PRU01091}; TPR repeat {ECO:0000256|PROSITE-ProRule:PRU00339}.
FT DOMAIN 12..67
FT /note="HTH cro/C1-type"
FT /evidence="ECO:0000259|PROSITE:PS50943"
FT DOMAIN 70..175
FT /note="OmpR/PhoB-type"
FT /evidence="ECO:0000259|PROSITE:PS51755"
FT REPEAT 804..837
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 884..917
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT DNA_BIND 70..175
FT /note="OmpR/PhoB-type"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01091"
SQ SEQUENCE 1067 AA; 117555 MW; 80BEB4BA5C52C9BA CRC64;
MDHEDLTFGE RLRARRSEAG LTQRELARRA NVSVRTVRYI EQGHIRNPRP ASIQQLASVL
DLPLHNADPS DAEKSPSAVF TINVLGPLAV YDEGRRVSLG ETVRARLLAL LALQPNTAVS
RDEIIDVLWG EQPPRSHVNL VHTYVARLRR LFASTGRQNG LPRLINARGG YLLEVDGDHL
DLVRFTELAA HGRESYRAGD PEAACDSYAR GLSCWRGAIL SDLDQDLRQH PAAVAVSRER
LAAVLDYADI AIALGRHDEA VVRLREVAAE EPLHEGLQAR LMIALAGTGQ QAAALRLFDE
LRDRLGDEMG IEPSAELQSA QLRVLRQQIP VAEAGDDQAP MAPGRNFLPY DIEDFTGRSA
EVDRLLQLAS AQEDSGRPAA SIIAVDGMPG VGKTTLVVHV AHRIAQRYPD AQLFLDLQGH
TEGHPPRTPR DALDSLLRQL GIAGELVPEG VDDCAALWRG TLADRRALIV LDNAADPGQL
RPILPGAKTC LTLITSRERL SSLEGVERIS LDVLPPDDAN ALFTRIVGAE RTVAHGSAVG
EALSLCGFLP LAIRIAAARL RDRSAWTPVT LAARLRDKNR RLIELSVGDR SAYAAFALSY
QQLTPRQQRI FRLLGEHPGF DINAYTAAAL CDITPDEAEL VLEQLVDMHL LRQTGLAETG
SVRYCFHDLL RYYARALSSG ERAESDRRAA LTRLLDYYLH TADLAAQLLE PFRHTAPVTG
IQPSAHIPVL SGQPAAMAWL DTERANLAAV IATANEYGWA AHCWQLTQRL WRFYFVRGHL
HDWITTHLIA LRSAEQLGEI AAQAELHKNL GLAYFRSGAF ADAWEHHRYA LDLDRETGDL
QGEAKTRNQL GFIRSRAGHY EEALDDHQQS AALYRRIGDR CGEARSMIGL GEAYFFAGRY
AESMARFQEA LTLSREVRDR WGENFALIGL GFTAKHMAQG ADAGKYLEEA LALARSAGDR
WCESVALTGL GYVHQGAGAA ADAIRHCEQA VALADEVGDR WGARLALSAL ANLYHEMGRP
IEALRYHQRA LELARALGNP NVEAEILAAL DAIESELRDH PLARRRN
//
