ID A0A318KB78_9NOCA Unreviewed; 988 AA.
AC A0A318KB78;
DT 10-OCT-2018, integrated into UniProtKB/TrEMBL.
DT 10-OCT-2018, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=Amino acid adenylation domain-containing protein/thioester reductase-like protein {ECO:0000313|EMBL:PXX71771.1};
GN ORFNames=DFR70_1011205 {ECO:0000313|EMBL:PXX71771.1};
OS Nocardia tenerifensis.
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Nocardiaceae;
OC Nocardia.
OX NCBI_TaxID=228006 {ECO:0000313|EMBL:PXX71771.1, ECO:0000313|Proteomes:UP000247569};
RN [1] {ECO:0000313|EMBL:PXX71771.1, ECO:0000313|Proteomes:UP000247569}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 44704 {ECO:0000313|EMBL:PXX71771.1,
RC ECO:0000313|Proteomes:UP000247569};
RA Goeker M.;
RT "Genomic Encyclopedia of Type Strains, Phase IV (KMG-IV): sequencing the
RT most valuable type-strain genomes for metagenomic binning, comparative
RT biology and taxonomic classification.";
RL Submitted (MAY-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PXX71771.1}.
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DR EMBL; QJKF01000001; PXX71771.1; -; Genomic_DNA.
DR RefSeq; WP_051186582.1; NZ_QJKF01000001.1.
DR AlphaFoldDB; A0A318KB78; -.
DR OrthoDB; 3691933at2; -.
DR Proteomes; UP000247569; Unassembled WGS sequence.
DR GO; GO:0044249; P:cellular biosynthetic process; IEA:UniProt.
DR GO; GO:1901566; P:organonitrogen compound biosynthetic process; IEA:UniProt.
DR CDD; cd05930; A_NRPS; 1.
DR Gene3D; 3.30.300.30; -; 1.
DR Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR010071; AA_adenyl_domain.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR036736; ACP-like_sf.
DR InterPro; IPR025110; AMP-bd_C.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR020845; AMP-binding_CS.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR042099; ANL_N_sf.
DR InterPro; IPR013120; Far_NAD-bd.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR009081; PP-bd_ACP.
DR InterPro; IPR006162; Ppantetheine_attach_site.
DR InterPro; IPR010080; Thioester_reductase-like_dom.
DR NCBIfam; TIGR01733; AA-adenyl-dom; 1.
DR NCBIfam; TIGR01746; Thioester-redct; 1.
DR PANTHER; PTHR44845:SF6; BETA-ALANINE-ACTIVATING ENZYME; 1.
DR PANTHER; PTHR44845; CARRIER DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00501; AMP-binding; 1.
DR Pfam; PF13193; AMP-binding_C; 1.
DR Pfam; PF07993; NAD_binding_4; 1.
DR Pfam; PF00550; PP-binding; 1.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR SUPFAM; SSF47336; ACP-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR PROSITE; PS00455; AMP_BINDING; 1.
DR PROSITE; PS50075; CARRIER; 1.
DR PROSITE; PS00012; PHOSPHOPANTETHEINE; 1.
PE 4: Predicted;
KW Phosphopantetheine {ECO:0000256|ARBA:ARBA00022450};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553}.
FT DOMAIN 496..571
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
SQ SEQUENCE 988 AA; 109150 MW; F3ECAF8558321904 CRC64;
MYCPIITELF APVVAARGAA VAIVEDHHRT TYEQLDALSE QLAQRLRDAG VGPGSLVPIV
AHRSAALVVA MLAVLKTGSA YTPIDRDNPS RRRAKIIEQC GAPVVLSTGS PSRESGTVTI
EFADGPVFKP LEKGAAYVVF TSGTTGTPKG VVVDQKAVIR LVRWHNDRFD TGADARTTLM
SGVGFDVSQW EIHSTLAAGA TAHVVDPAVR ADPAALLDFY AEHAITHAFV PTVLTPDVVA
APRPADLALR YLFCAGEKLP PIRTGPLPYT LVDYYGPTEA TIFATCRVVD PAAEQAPSIG
TPISDTEAFI LDDELGEVDP GAVGELCLAG TCLARGYLGD RDRTEDRFVW SPRLERRLYR
TGDLARWLPD GSIEFLGRSD DQVKIRGYRI ELGDIEAAIL DNRLVKHAVV VVDDQDRASS
AKRLAAFVVP REHDTDPDAL VRTLRVHMRD ELPDYMQPGI YQCRTDLPVT ANGKIDRAGL
RADLAQDRDV PMPDAGFEGD IEHAVAEIWR EVLGHNRFSA TDNFFDVGGH SLLATALIGE
ISRRVGARVY IWDFYGDPTV RGLAAAINSR GDEAPDWEGE PVRELADDIH LPDGVDYRTG
WDERQLTDPS HTLLTGATGI IGVHLLGRLH ESTDAVVHCL IRAGSPALAR ERLRAVVARY
EVTAVDWDRV RVHAGDLAEP RFGLDADEYA ALASDVDVIY HSASAANFIQ SYAYIRRDNV
EGLRTVLRFA GDDHVKPLML VSSISVYSWG HLFTGKSTMY EDDDIDQNLR AVVTDLGYMR
SKWVMEKVAE LAEAQGLPVM KFRLGYALCD ARTGHAATYQ WWPRLVKTCV ALGAIPDLQN
LREGLITVDY IVDAIAAIGR DPGAAGKNFN VVPAQDRIVT LRRFFELLEE HFGYEFRVLP
YEQWVDLWKD DPQAPLYPLL NMFHDHMLDR RSTIELYQNT YLWDKTNVTE HLVGTGVEEP
TLTPEILDRY LRRVLAEPYV PAAMADAR
//
