ID A0A318KUH9_9NOCA Unreviewed; 649 AA.
AC A0A318KUH9;
DT 10-OCT-2018, integrated into UniProtKB/TrEMBL.
DT 10-OCT-2018, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE SubName: Full=Acetoacetyl-CoA synthetase {ECO:0000313|EMBL:PXX68411.1};
GN ORFNames=DFR70_10291 {ECO:0000313|EMBL:PXX68411.1};
OS Nocardia tenerifensis.
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Nocardiaceae;
OC Nocardia.
OX NCBI_TaxID=228006 {ECO:0000313|EMBL:PXX68411.1, ECO:0000313|Proteomes:UP000247569};
RN [1] {ECO:0000313|EMBL:PXX68411.1, ECO:0000313|Proteomes:UP000247569}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 44704 {ECO:0000313|EMBL:PXX68411.1,
RC ECO:0000313|Proteomes:UP000247569};
RA Goeker M.;
RT "Genomic Encyclopedia of Type Strains, Phase IV (KMG-IV): sequencing the
RT most valuable type-strain genomes for metagenomic binning, comparative
RT biology and taxonomic classification.";
RL Submitted (MAY-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PXX68411.1}.
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DR EMBL; QJKF01000002; PXX68411.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A318KUH9; -.
DR OrthoDB; 9803968at2; -.
DR Proteomes; UP000247569; Unassembled WGS sequence.
DR GO; GO:0030729; F:acetoacetate-CoA ligase activity; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0006629; P:lipid metabolic process; IEA:InterPro.
DR Gene3D; 3.30.300.30; -; 1.
DR Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR InterPro; IPR005914; Acac_CoA_synth.
DR InterPro; IPR032387; ACAS_N.
DR InterPro; IPR025110; AMP-bd_C.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR020845; AMP-binding_CS.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR042099; ANL_N_sf.
DR NCBIfam; TIGR01217; ac_ac_CoA_syn; 1.
DR PANTHER; PTHR42921; ACETOACETYL-COA SYNTHETASE; 1.
DR PANTHER; PTHR42921:SF1; ACETOACETYL-COA SYNTHETASE; 1.
DR Pfam; PF16177; ACAS_N; 1.
DR Pfam; PF00501; AMP-binding; 1.
DR Pfam; PF13193; AMP-binding_C; 1.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR PROSITE; PS00455; AMP_BINDING; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Ligase {ECO:0000256|ARBA:ARBA00022598};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741}.
FT DOMAIN 35..86
FT /note="Acetyl-coenzyme A synthetase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF16177"
FT DOMAIN 91..465
FT /note="AMP-dependent synthetase/ligase"
FT /evidence="ECO:0000259|Pfam:PF00501"
FT DOMAIN 532..607
FT /note="AMP-binding enzyme C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13193"
SQ SEQUENCE 649 AA; 70230 MW; 7EED8FBC81B28E93 CRC64;
MQPQWVPTEQ DIADARITDF AKFAEARTGV AKPDYHTLWQ WSVDELADFW HAVWDYFELG
DIAGEVLADT TMPGAQWFPG TRLNYVDQLV RQFRTDRPAI IAVGEDTPTR EVSWAELIDE
TAALAQTLRS LGVRPGDRVA GYLPNIPEAV IAFLATASIG AVWSACGQDY SAKAALDRLG
QLEPTVLITV DGYRFGGKAH DKREDIAALR AGLGTLRATI AADRLGLDVA DATPWREAVA
HDDAAPAVIT TETVDFDHPL WIVFSSGTTG LPKGIVHGHG GVLLEHLKAV ALQTDIGPND
TFFWYTSPSW MMWNFQVSGL LVGATIVCYD GSPTHPAADG LWRIAAETGT TVLGTSPGYA
LACIKAGAVP RAAHDLSALR AIGITGASLP TSTAIWLGAN IGDHVQVNSI SGGTDVVSAF
LGGARTVASW PGELSTRFLG AAIESFDGTG QPVRGEVGEL VITKPMPSMP VRFWHDPDGK
RYHDAYFDMY PGVWRHGDWI TITDRESIVV HGRSDSTLNR HGIRMGSADI YQAVERLPEI
AEALVIGAEQ PDGGYWMPLF VVLAPGAELT DDLKTRICTT IRTEVSPRHV PDEILLAPGI
PHTRTGKKLE VPIKKLFQGA DASRVVERSA VDQPELLDWY AVQRPSAVG
//
