ID   A0A318LUJ6_9PSEU        Unreviewed;       489 AA.
AC   A0A318LUJ6;
DT   10-OCT-2018, integrated into UniProtKB/TrEMBL.
DT   10-OCT-2018, sequence version 1.
DT   27-MAR-2024, entry version 15.
DE   SubName: Full=Penicillin-binding protein {ECO:0000313|EMBL:PXY37491.1};
GN   ORFNames=BA062_02230 {ECO:0000313|EMBL:PXY37491.1};
OS   Prauserella flavalba.
OC   Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC   Pseudonocardiaceae; Prauserella.
OX   NCBI_TaxID=1477506 {ECO:0000313|EMBL:PXY37491.1, ECO:0000313|Proteomes:UP000247892};
RN   [1] {ECO:0000313|EMBL:PXY37491.1, ECO:0000313|Proteomes:UP000247892}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=YIM 121212 {ECO:0000313|EMBL:PXY37491.1,
RC   ECO:0000313|Proteomes:UP000247892};
RA   Ruckert C., Albersmeier A., Jiang C.-L., Jiang Y., Kalinowski J.,
RA   Schneider O., Winkler A., Zotchev S.B.;
RT   "Draft genome sequence of Prauserella sp. YIM 121212, isolated from
RT   alkaline soil.";
RL   Submitted (JUL-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the asparaginase 1 family.
CC       {ECO:0000256|ARBA:ARBA00010518}.
CC   -!- SIMILARITY: Belongs to the transpeptidase family.
CC       {ECO:0000256|ARBA:ARBA00007171}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PXY37491.1}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; MASU01000002; PXY37491.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A318LUJ6; -.
DR   OrthoDB; 9766847at2; -.
DR   Proteomes; UP000247892; Unassembled WGS sequence.
DR   GO; GO:0008658; F:penicillin binding; IEA:InterPro.
DR   GO; GO:0006520; P:amino acid metabolic process; IEA:InterPro.
DR   Gene3D; 3.40.710.10; DD-peptidase/beta-lactamase superfamily; 1.
DR   Gene3D; 3.90.1310.10; Penicillin-binding protein 2a (Domain 2); 1.
DR   InterPro; IPR020827; Asparaginase/glutaminase_AS1.
DR   InterPro; IPR012338; Beta-lactam/transpept-like.
DR   InterPro; IPR036138; PBP_dimer_sf.
DR   InterPro; IPR001460; PCN-bd_Tpept.
DR   PANTHER; PTHR30627; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE; 1.
DR   PANTHER; PTHR30627:SF24; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE PBPA; 1.
DR   Pfam; PF00905; Transpeptidase; 1.
DR   SUPFAM; SSF56601; beta-lactamase/transpeptidase-like; 1.
DR   SUPFAM; SSF56519; Penicillin binding protein dimerisation domain; 1.
DR   PROSITE; PS00144; ASN_GLN_ASE_1; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000247892}.
FT   DOMAIN          159..481
FT                   /note="Penicillin-binding protein transpeptidase"
FT                   /evidence="ECO:0000259|Pfam:PF00905"
FT   ACT_SITE        472
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU10099"
SQ   SEQUENCE   489 AA;  51463 MW;  0538D985D583301C CRC64;
     MNTPLRKVGV AMLVMVTLLL VNATYIQVVQ ADDYRTDSRN SRVLLDEYSR ERGKIVSEEA
     GQVLAGVKPT DDQLKFQRTY LDGPMYAPVT GYYSVLYGAG GLERAEDEFL NGSDPRLFVR
     RLSDMITGRD PRGGNVRLTV RPSVQEAAYN AMVQNGYTGS VVALDPKTGD ILAMVSTPSY
     DPGRLASHDA NEQQDAWTSF TEDPANPMLN RAIRENYPPG STFKIVTTAA ALENGMTADS
     QVTSAAETTL PGTSTTLENY GGATCPGSTL ADALKYSCNT AFAEIAGQLG KEKLEATAAN
     FGIGMDDLAI PMGVVPSGLG DLESDAALYQ SGIGQRDVRL TPLQDALLAA TVANDGVAMK
     PQLIKALLAP DLSTIEEFSP EELTGEPAMS AENAQVLTDM MIQSESNTSG GGKDESLKIA
     SKTGTAEHGT DPKATPPHAW YTAFAPYDDP KIAVAVIVES GGNRGLAATG GTVAAEIARS
     TIAAALGGG
//