ID   A0A318SQG3_9RHOB        Unreviewed;       998 AA.
AC   A0A318SQG3;
DT   10-OCT-2018, integrated into UniProtKB/TrEMBL.
DT   10-OCT-2018, sequence version 1.
DT   24-JAN-2024, entry version 16.
DE   SubName: Full=Heterotetrameric sarcosine oxidase alpha subunit {ECO:0000313|EMBL:PYE84120.1};
GN   ORFNames=DFP88_103487 {ECO:0000313|EMBL:PYE84120.1};
OS   Pseudoroseicyclus aestuarii.
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC   Paracoccaceae; Pseudoroseicyclus.
OX   NCBI_TaxID=1795041 {ECO:0000313|EMBL:PYE84120.1, ECO:0000313|Proteomes:UP000248311};
RN   [1] {ECO:0000313|EMBL:PYE84120.1, ECO:0000313|Proteomes:UP000248311}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CECT 9025 {ECO:0000313|EMBL:PYE84120.1,
RC   ECO:0000313|Proteomes:UP000248311};
RA   Whitman W.;
RT   "Genomic Encyclopedia of Type Strains, Phase III (KMG-III): the genomes of
RT   soil and plant-associated and newly described type strains.";
RL   Submitted (JUN-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the GcvT family.
CC       {ECO:0000256|ARBA:ARBA00008609}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PYE84120.1}.
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DR   EMBL; QJTE01000003; PYE84120.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A318SQG3; -.
DR   OrthoDB; 5287468at2; -.
DR   Proteomes; UP000248311; Unassembled WGS sequence.
DR   GO; GO:0008115; F:sarcosine oxidase activity; IEA:InterPro.
DR   GO; GO:0046653; P:tetrahydrofolate metabolic process; IEA:InterPro.
DR   Gene3D; 3.10.20.440; 2Fe-2S iron-sulphur cluster binding domain, sarcosine oxidase, alpha subunit, N-terminal domain; 1.
DR   Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR   InterPro; IPR042204; 2Fe-2S-bd_N.
DR   InterPro; IPR036188; FAD/NAD-bd_sf.
DR   InterPro; IPR023753; FAD/NAD-binding_dom.
DR   InterPro; IPR028896; GCST/YgfZ/DmdA.
DR   InterPro; IPR013977; GCV_T_C.
DR   InterPro; IPR006222; GCV_T_N.
DR   InterPro; IPR029043; GcvT/YgfZ_C.
DR   InterPro; IPR006277; Sarcosine_oxidase_asu.
DR   InterPro; IPR041117; SoxA_A3.
DR   InterPro; IPR027266; TrmE/GcvT_dom1.
DR   NCBIfam; TIGR01372; soxA; 1.
DR   PANTHER; PTHR43757; AMINOMETHYLTRANSFERASE; 1.
DR   PANTHER; PTHR43757:SF2; AMINOMETHYLTRANSFERASE, MITOCHONDRIAL; 1.
DR   Pfam; PF13510; Fer2_4; 1.
DR   Pfam; PF01571; GCV_T; 1.
DR   Pfam; PF08669; GCV_T_C; 1.
DR   Pfam; PF07992; Pyr_redox_2; 1.
DR   Pfam; PF17806; SO_alpha_A3; 1.
DR   PIRSF; PIRSF037980; SoxA; 1.
DR   PRINTS; PR00368; FADPNR.
DR   PRINTS; PR00411; PNDRDTASEI.
DR   SUPFAM; SSF101790; Aminomethyltransferase beta-barrel domain; 1.
DR   SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
DR   SUPFAM; SSF103025; Folate-binding domain; 1.
PE   3: Inferred from homology;
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW   Reference proteome {ECO:0000313|Proteomes:UP000248311}.
FT   DOMAIN          170..434
FT                   /note="FAD/NAD(P)-binding"
FT                   /evidence="ECO:0000259|Pfam:PF07992"
FT   DOMAIN          516..599
FT                   /note="SoxA A3"
FT                   /evidence="ECO:0000259|Pfam:PF17806"
FT   DOMAIN          615..879
FT                   /note="Aminomethyltransferase folate-binding"
FT                   /evidence="ECO:0000259|Pfam:PF01571"
FT   DOMAIN          905..990
FT                   /note="Glycine cleavage T-protein C-terminal barrel"
FT                   /evidence="ECO:0000259|Pfam:PF08669"
FT   REGION          445..472
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   998 AA;  106555 MW;  B3F153FD805024E3 CRC64;
     MSRRLETGGL FIDRNAPMGF TFDGKDRGGF GGDTLASALL ACGQLVMGRS FKYHRQRGPV
     SCGAEEPNAL VGLGEGGLFE PNARATITPL TEGLRAISQN RWPSLAFDIG AVNAKLSKFL
     PAGFYYKTFL WPRAFWKHVY EPAIRRSAGL GKPPSQPDAD RYEQVNTAAD VLIAGGGVAG
     LAAAMEAGRN GARVILMEQG PRWGGRALID APLTGETIDG QPAADWIEMA VDTLETMPNV
     TMRLHTQVSG VFDHGFALAE ERCADAGPAP VRARLWRIRA RRIVTAQGAI ERPLAFAGND
     VPGVMLAGAV RDYAVGYGVA VGERVVVVTA GDDGYRTAIA LVEAGLAVPA LLDVRRGATG
     PLVERAQALG IRIEEGRGIA HVSGGQSVTG VSICAQDGPG EVIEEIACDA VAMSGGWSPA
     VHLWSQAGGK LTWDEGAAMF RPDHARPPTG ADGSGFVLPA GGSDGAASTE DALRSGAEAG
     RLAAEGGVPA DLAPPQAAPM PQVWVMPRDA GLALREKMWL DFQNDVKVSD VELAAREGYR
     SVEHAKRYTT LGMATDQGKL SNIGGLATLG HALGEAIPQV GTTTFRPPWT PIILGSIAGS
     ATGAQFQPVR RTPMQDWHDA NGADYEPVGQ WRRPYSYPRE GEDREAAAQR ETRAVREAVG
     LLDASTLGKI VVKGPDAGRF MDMIYTNMMS NLAVGRCRYG LICNDSGFLM DDGVVARLSE
     DTWLCHTTTG GAEHIHAHME EWLQTEWWDW QVYTANLTEQ FAQVVVAGPQ ARKLLDRLGG
     MDVSREAMPF MSWAEGSLHG FDARVFRISF SGEVSYEVSV RASEGAELWQ ALLEEGEDLG
     VTPYGTEAMH ILRAEKGYVM IGEESDGTIT PQDLNLGWAV SKKKADFIGK RGLTRSHLAD
     PERPRLVGLR SLDGTVIEAG AQVVGPGVTP TGQNATEGRV TSSYHSPTFG HGIAMALIRR
     GPERLGETVE VTRIGGGRQK AVLVDPVLYD AKGDRLNG
//