ID   A0A318XIV6_9FIRM        Unreviewed;      1069 AA.
AC   A0A318XIV6;
DT   10-OCT-2018, integrated into UniProtKB/TrEMBL.
DT   10-OCT-2018, sequence version 1.
DT   27-MAR-2024, entry version 19.
DE   SubName: Full=Diguanylate cyclase (GGDEF)-like protein {ECO:0000313|EMBL:PYG85628.1};
GN   ORFNames=LY28_03316 {ECO:0000313|EMBL:PYG85628.1};
OS   Ruminiclostridium sufflavum DSM 19573.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Oscillospiraceae;
OC   Ruminiclostridium.
OX   NCBI_TaxID=1121337 {ECO:0000313|EMBL:PYG85628.1, ECO:0000313|Proteomes:UP000248132};
RN   [1] {ECO:0000313|EMBL:PYG85628.1, ECO:0000313|Proteomes:UP000248132}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 19573 {ECO:0000313|EMBL:PYG85628.1,
RC   ECO:0000313|Proteomes:UP000248132};
RA   Kyrpides N.;
RT   "Genomic Encyclopedia of Type Strains, Phase I: the one thousand microbial
RT   genomes (KMG-I) project.";
RL   Submitted (JUN-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PYG85628.1}.
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DR   EMBL; QKMR01000025; PYG85628.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A318XIV6; -.
DR   Proteomes; UP000248132; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR   GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR   CDD; cd01948; EAL; 1.
DR   CDD; cd01949; GGDEF; 1.
DR   CDD; cd06267; PBP1_LacI_sugar_binding-like; 1.
DR   Gene3D; 3.30.70.270; -; 2.
DR   Gene3D; 3.40.50.2300; -; 2.
DR   Gene3D; 3.20.20.450; EAL domain; 1.
DR   InterPro; IPR001633; EAL_dom.
DR   InterPro; IPR035919; EAL_sf.
DR   InterPro; IPR000160; GGDEF_dom.
DR   InterPro; IPR046335; LacI/GalR-like_sensor.
DR   InterPro; IPR029787; Nucleotide_cyclase.
DR   InterPro; IPR028082; Peripla_BP_I.
DR   InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR   NCBIfam; TIGR00254; GGDEF; 1.
DR   PANTHER; PTHR33121; CYCLIC DI-GMP PHOSPHODIESTERASE PDEF; 1.
DR   PANTHER; PTHR33121:SF78; CYCLIC DI-GMP PHOSPHODIESTERASE PDEI-RELATED; 1.
DR   Pfam; PF00563; EAL; 1.
DR   Pfam; PF00990; GGDEF; 2.
DR   Pfam; PF13377; Peripla_BP_3; 1.
DR   SMART; SM00052; EAL; 1.
DR   SMART; SM00267; GGDEF; 1.
DR   SUPFAM; SSF141868; EAL domain-like; 1.
DR   SUPFAM; SSF55073; Nucleotide cyclase; 2.
DR   SUPFAM; SSF53822; Periplasmic binding protein-like I; 1.
DR   PROSITE; PS50883; EAL; 1.
DR   PROSITE; PS50887; GGDEF; 2.
PE   4: Predicted;
KW   DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW   DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW   Reference proteome {ECO:0000313|Proteomes:UP000248132}.
FT   DOMAIN          505..644
FT                   /note="GGDEF"
FT                   /evidence="ECO:0000259|PROSITE:PS50887"
FT   DOMAIN          666..799
FT                   /note="GGDEF"
FT                   /evidence="ECO:0000259|PROSITE:PS50887"
FT   DOMAIN          807..1063
FT                   /note="EAL"
FT                   /evidence="ECO:0000259|PROSITE:PS50883"
SQ   SEQUENCE   1069 AA;  124392 MW;  EB5533CB92ABB887 CRC64;
     MDILMRKRIG VLIGEAEAPH CMTLLTGISN EAKRLDFDLF VYTNFNQTMG QERYVRGEGS
     IYELINFNML DAVLIVPESL RIPGIARRLE KKVQREFNGP VLCIDYDSEF FPTMKFDDID
     LMKRIIHHLT DVHGFTSIAF ISGPLHHEHA INRLTAYKEA LMERQIPIDE SLIFEGTFYY
     ECTGKMADEL MKREKLPQAV ACANQLMAVD IYDELTKRGL SIPEDIVVTG YDATDRKVKE
     NYYITSTLRT GGALGARAVR YLYEKLYNTV LPEQEDDEDR LLIWNTCGCR PTHEEINIPL
     DYSIWKNAEI NSFENHFLKY NFMMEDLISS ENPQECFDRC RTYLPDLGDY SDIYICLNED
     WLTKQDTKAI YSGKILVVIQ DHKSNIGKVI PVESFPKLQM LPYIEIPREK TMIYYFMPLH
     FYGIAFGYAV ICFEDKPVFF NRNYRHWIHN MDSAIQSQRQ EHALHEMYDK LERYAVKDLL
     TGIYSSNGFE LHSMSIYEDA KASEQNLICI VGDVNNLKTI NDRYGHEWGD KALRILADAL
     ENQIKMKKLK GMAFRTGGDE FNLLLTGAYT EDSVKNIIDE IDDYVEMAKD LYDMPTNVTV
     SLGGCLSVCT EDKPLSEIIA EADQQMYNQK FIYKSSNRNN VQTRIWNKAY FEAETERIIK
     ENSLCKKYAF ISMRIHNYEL YLNIYGRQKG NDIIRHLGEL VDIHLPEDSI ATKYSDRQYV
     IFFPYTEVSD IENWFLTFNM NIEGYELQTR SDYSMKINSG IYLYKGQGKY TVKDMIERAN
     FALQTGIDDV KGFVVYDERM RDKFIEETEI IRSFDEAMEK NEFQIYLQPQ HYIQMKDKVL
     SAEALVRWIK ADGTIIYPNS FIPAFEKNGF IAKLDRHIME LTCKFINTHI EEAWCRDIRI
     AVNVSKIDLE YEHFLEYYID TKNKYNIPDG AIEIEFTESA VFEDYNTFKN IMEKLQQSGF
     SCALDDFGAG SSSLNLLKEL PVDVIKMDRL FFKESNNRQR DNSVITSVVA MAKGLGMKIV
     AEGIEDDERV KFLREIGCDV IQGFIYSKPL SVNNFIDYVS GYMNKLEQY
//