ID A0A318XSG8_9FIRM Unreviewed; 328 AA.
AC A0A318XSG8;
DT 10-OCT-2018, integrated into UniProtKB/TrEMBL.
DT 10-OCT-2018, sequence version 1.
DT 24-JAN-2024, entry version 15.
DE RecName: Full=DNA polymerase III subunit delta' {ECO:0000256|ARBA:ARBA00014363};
DE EC=2.7.7.7 {ECO:0000256|ARBA:ARBA00012417};
GN ORFNames=LY28_01014 {ECO:0000313|EMBL:PYG89191.1};
OS Ruminiclostridium sufflavum DSM 19573.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Oscillospiraceae;
OC Ruminiclostridium.
OX NCBI_TaxID=1121337 {ECO:0000313|EMBL:PYG89191.1, ECO:0000313|Proteomes:UP000248132};
RN [1] {ECO:0000313|EMBL:PYG89191.1, ECO:0000313|Proteomes:UP000248132}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 19573 {ECO:0000313|EMBL:PYG89191.1,
RC ECO:0000313|Proteomes:UP000248132};
RA Kyrpides N.;
RT "Genomic Encyclopedia of Type Strains, Phase I: the one thousand microbial
RT genomes (KMG-I) project.";
RL Submitted (JUN-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) =
CC diphosphate + DNA(n+1); Xref=Rhea:RHEA:22508, Rhea:RHEA-COMP:17339,
CC Rhea:RHEA-COMP:17340, ChEBI:CHEBI:33019, ChEBI:CHEBI:61560,
CC ChEBI:CHEBI:173112; EC=2.7.7.7;
CC Evidence={ECO:0000256|ARBA:ARBA00024632};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PYG89191.1}.
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DR EMBL; QKMR01000004; PYG89191.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A318XSG8; -.
DR OrthoDB; 9810148at2; -.
DR Proteomes; UP000248132; Unassembled WGS sequence.
DR GO; GO:0009360; C:DNA polymerase III complex; IEA:InterPro.
DR GO; GO:0008408; F:3'-5' exonuclease activity; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003887; F:DNA-directed DNA polymerase activity; IEA:UniProtKB-KW.
DR GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR004622; DNA_pol_HolB.
DR InterPro; IPR015199; DNA_pol_III_delta_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR NCBIfam; TIGR00678; holB; 1.
DR PANTHER; PTHR11669:SF8; DNA POLYMERASE III SUBUNIT DELTA; 1.
DR PANTHER; PTHR11669; REPLICATION FACTOR C / DNA POLYMERASE III GAMMA-TAU SUBUNIT; 1.
DR Pfam; PF13177; DNA_pol3_delta2; 1.
DR Pfam; PF09115; DNApol3-delta_C; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 4: Predicted;
KW DNA replication {ECO:0000256|ARBA:ARBA00022705};
KW DNA-directed DNA polymerase {ECO:0000256|ARBA:ARBA00022932};
KW Nucleotidyltransferase {ECO:0000256|ARBA:ARBA00022695};
KW Reference proteome {ECO:0000313|Proteomes:UP000248132};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 204..318
FT /note="DNA polymerase III delta subunit C-terminal"
FT /evidence="ECO:0000259|Pfam:PF09115"
SQ SEQUENCE 328 AA; 37115 MW; 4A1DF7A216EC9090 CRC64;
MLGHQKVLKT LRAAIKNNNV SHAYIFEGAN GIGKRETALA FSSVLMCEAE DGPCGKCKAC
LLFQQGSHPD FQEIYAEDDK SISVENIRNL LKGLVIRPLY SEYKIFLINN ADKMTVQAQN
ALLKSLEEPP PYVVFILAVQ SSAAMTPTIR SRCRRIFFNK LTYEEIMGIL KEKYGNSKPE
WDFIVPYSDG VIGTAIGLLD SPHYLEIRDE VLDKVVQLLN SQDLDLFSLY GLFEKNDDKI
DFILRVMLLF FRDMLVYRQT GDFRILINSD KKDMIIKNTG IKVSGIMKCI SAVWSAKKSL
EVNANFQLAI EVMLMKIQQN SSKQSVVS
//
