ID   A0A318XYT8_9FIRM        Unreviewed;       586 AA.
AC   A0A318XYT8;
DT   10-OCT-2018, integrated into UniProtKB/TrEMBL.
DT   10-OCT-2018, sequence version 1.
DT   24-JAN-2024, entry version 12.
DE   SubName: Full=Squalene/oxidosqualene cyclase-like protein {ECO:0000313|EMBL:PYG88027.1};
GN   ORFNames=LY28_01737 {ECO:0000313|EMBL:PYG88027.1};
OS   Ruminiclostridium sufflavum DSM 19573.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Oscillospiraceae;
OC   Ruminiclostridium.
OX   NCBI_TaxID=1121337 {ECO:0000313|EMBL:PYG88027.1, ECO:0000313|Proteomes:UP000248132};
RN   [1] {ECO:0000313|EMBL:PYG88027.1, ECO:0000313|Proteomes:UP000248132}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 19573 {ECO:0000313|EMBL:PYG88027.1,
RC   ECO:0000313|Proteomes:UP000248132};
RA   Kyrpides N.;
RT   "Genomic Encyclopedia of Type Strains, Phase I: the one thousand microbial
RT   genomes (KMG-I) project.";
RL   Submitted (JUN-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- PATHWAY: Secondary metabolite biosynthesis; hopanoid biosynthesis.
CC       {ECO:0000256|ARBA:ARBA00004999}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PYG88027.1}.
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DR   EMBL; QKMR01000008; PYG88027.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A318XYT8; -.
DR   UniPathway; UPA00337; -.
DR   Proteomes; UP000248132; Unassembled WGS sequence.
DR   GO; GO:0005811; C:lipid droplet; IEA:InterPro.
DR   GO; GO:0016866; F:intramolecular transferase activity; IEA:InterPro.
DR   GO; GO:0016104; P:triterpenoid biosynthetic process; IEA:InterPro.
DR   Gene3D; 1.50.10.20; -; 3.
DR   InterPro; IPR032696; SQ_cyclase_C.
DR   InterPro; IPR032697; SQ_cyclase_N.
DR   InterPro; IPR018333; Squalene_cyclase.
DR   InterPro; IPR008930; Terpenoid_cyclase/PrenylTrfase.
DR   PANTHER; PTHR11764:SF20; LANOSTEROL SYNTHASE; 1.
DR   PANTHER; PTHR11764; TERPENE CYCLASE/MUTASE FAMILY MEMBER; 1.
DR   Pfam; PF13243; SQHop_cyclase_C; 1.
DR   Pfam; PF13249; SQHop_cyclase_N; 1.
DR   SUPFAM; SSF48239; Terpenoid cyclases/Protein prenyltransferases; 2.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000248132};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT   DOMAIN          204..265
FT                   /note="Squalene cyclase N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF13249"
FT   DOMAIN          281..578
FT                   /note="Squalene cyclase C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF13243"
SQ   SEQUENCE   586 AA;  65941 MW;  E42417D87ADB80AD CRC64;
     MELVHLKEAV NSSIDRALVN VFENQYMGTF WQGDIYYNAY PTAVAIITNK ILGITEPEWE
     SKAAHCIMGL QRRDGSWGIL DKQALPLPNL DEDKMEEMLE LKSAAARNTV VCILALELLD
     VYPECVAKGK EYMKTVDEKY IDPFTEIFLA CFGRKKWKDI KVPPIEMMLI PANSKFGFNR
     FLPAWVRDGA AGGILLKTLR QKKGLWSPIR RMAIKKAEKM LLNNQLSNGG WFGTFQPTVY
     PTLALAELGH DLNSDVIQRA LGFLQTRRRE ENGYVHRFWL PVWDTSFALL ALASAGLTDS
     NHNVAKAKYY IINSQFRNGS WGFCPEVNIY PDCDDTAVAM QALSKIGVNK DYLMKSAEWL
     ERRQNKDGGW AAFVKEQAKK TPGTLPTTIE DSMVILKDPS VADVTGHVMI ALGEVGYRVG
     HPSIDKAISF LKKDQLPSGP WYGRWGLCYI YAVTRVLKAL QVIGEDMNSD YVQKAIKWLV
     EHQNSDGGWG ECYVSYFKEE YAGIGMSTAV HTSWALTTLI SVAPKYSSAI EKGAKYILET
     QCKDGNWPSP HTVGALEVYE NTNYSRVFPL MALGEYRKFI SKGGDF
//