ID A0A319ABT6_ASPLB Unreviewed; 380 AA.
AC A0A319ABT6;
DT 10-OCT-2018, integrated into UniProtKB/TrEMBL.
DT 10-OCT-2018, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE SubName: Full=S-adenosyl-L-methionine-dependent methyltransferase {ECO:0000313|EMBL:PYH57526.1};
GN ORFNames=BO96DRAFT_390698 {ECO:0000313|EMBL:PYH57526.1};
OS Aspergillus lacticoffeatus (strain CBS 101883).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC Aspergillus subgen. Circumdati.
OX NCBI_TaxID=1450533 {ECO:0000313|EMBL:PYH57526.1, ECO:0000313|Proteomes:UP000247441};
RN [1] {ECO:0000313|EMBL:PYH57526.1, ECO:0000313|Proteomes:UP000247441}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 101883 {ECO:0000313|EMBL:PYH57526.1,
RC ECO:0000313|Proteomes:UP000247441};
RG DOE Joint Genome Institute;
RA Vesth T.C., Nybo J., Theobald S., Brandl J., Frisvad J.C., Nielsen K.F.,
RA Lyhne E.K., Kogle M.E., Kuo A., Riley R., Clum A., Nolan M., Lipzen A.,
RA Salamov A., Henrissat B., Wiebenga A., De Vries R.P., Grigoriev I.V.,
RA Mortensen U.H., Andersen M.R., Baker S.E.;
RT "The genomes of Aspergillus section Nigri reveals drivers in fungal
RT speciation.";
RL Submitted (DEC-2016) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; KZ821346; PYH57526.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A319ABT6; -.
DR OrthoDB; 1067404at2759; -.
DR Proteomes; UP000247441; Unassembled WGS sequence.
DR GO; GO:0008171; F:O-methyltransferase activity; IEA:InterPro.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR GO; GO:0044550; P:secondary metabolite biosynthetic process; IEA:UniProt.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR016461; COMT-like.
DR InterPro; IPR001077; O_MeTrfase_dom.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR43712:SF1; HYPOTHETICAL O-METHYLTRANSFERASE (EUROFUNG)-RELATED; 1.
DR PANTHER; PTHR43712; PUTATIVE (AFU_ORTHOLOGUE AFUA_4G14580)-RELATED; 1.
DR Pfam; PF00891; Methyltransf_2; 1.
DR PIRSF; PIRSF005739; O-mtase; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS51683; SAM_OMT_II; 1.
PE 4: Predicted;
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603,
KW ECO:0000313|EMBL:PYH57526.1};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW Transferase {ECO:0000313|EMBL:PYH57526.1}.
FT DOMAIN 170..357
FT /note="O-methyltransferase"
FT /evidence="ECO:0000259|Pfam:PF00891"
FT ACT_SITE 287
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR005739-1"
SQ SEQUENCE 380 AA; 42870 MW; A1DCDC449040EB21 CRC64;
MEALAQEVRR LVEAGDEKTR KDVLDALQKL SVSIETPDDT VQRLTFYNMQ LAGIRIGIDL
KLFELLLEGP LTVDELSQKT GANSVFLARL LRYLASYYAV EEVSKDTFTA SGISKTFAVS
GHQAAVGHMW NNCGQIIQVL PSWLKENNYP DIQDNVKTPF QKALNTDVPA FIYMQQNPEA
LGYFVEHMMA NRAGMPTFLD AYPVLEKATG LSPERALFVD IGGGLGHQAI SFKQRYPQLE
GRVIVQDLAQ TLAHAIEFPG VEKQVYDFFT PQVVKGAKFY YLRNIFHDWP DHKVLEIIKN
TIEAMAPDSF LLIDEMVLPN TGVHWQQAQL DMLMMATLGA RERTEEQWYR LAEEAGLTIN
KVYTYTVSLR DSIIEAVPKA
//
