ID A0A319CI47_9EURO Unreviewed; 908 AA.
AC A0A319CI47;
DT 10-OCT-2018, integrated into UniProtKB/TrEMBL.
DT 10-OCT-2018, sequence version 1.
DT 24-JAN-2024, entry version 21.
DE RecName: Full=Voltage-gated chloride channel {ECO:0008006|Google:ProtNLM};
GN ORFNames=BO82DRAFT_275498 {ECO:0000313|EMBL:PYH85335.1};
OS Aspergillus uvarum CBS 121591.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus.
OX NCBI_TaxID=1448315 {ECO:0000313|EMBL:PYH85335.1, ECO:0000313|Proteomes:UP000248340};
RN [1] {ECO:0000313|EMBL:PYH85335.1, ECO:0000313|Proteomes:UP000248340}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 121591 {ECO:0000313|EMBL:PYH85335.1,
RC ECO:0000313|Proteomes:UP000248340};
RG DOE Joint Genome Institute;
RA Vesth T.C., Nybo J., Theobald S., Brandl J., Frisvad J.C., Nielsen K.F.,
RA Lyhne E.K., Kogle M.E., Kuo A., Riley R., Clum A., Nolan M., Lipzen A.,
RA Salamov A., Henrissat B., Wiebenga A., De Vries R.P., Grigoriev I.V.,
RA Mortensen U.H., Andersen M.R., Baker S.E.;
RT "The genomes of Aspergillus section Nigri reveals drivers in fungal
RT speciation.";
RL Submitted (DEC-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; KZ821680; PYH85335.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A319CI47; -.
DR VEuPathDB; FungiDB:BO82DRAFT_275498; -.
DR OrthoDB; 150430at2759; -.
DR Proteomes; UP000248340; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005247; F:voltage-gated chloride channel activity; IEA:InterPro.
DR CDD; cd03684; ClC_3_like; 1.
DR Gene3D; 1.10.3080.10; Clc chloride channel; 1.
DR InterPro; IPR046342; CBS_dom_sf.
DR InterPro; IPR014743; Cl-channel_core.
DR InterPro; IPR001807; Cl-channel_volt-gated.
DR PANTHER; PTHR45711; CHLORIDE CHANNEL PROTEIN; 1.
DR PANTHER; PTHR45711:SF3; CLC CHANNEL; 1.
DR Pfam; PF00654; Voltage_CLC; 1.
DR PRINTS; PR00762; CLCHANNEL.
DR SUPFAM; SSF54631; CBS-domain pair; 1.
DR SUPFAM; SSF81340; Clc chloride channel; 1.
PE 4: Predicted;
KW Chloride {ECO:0000256|ARBA:ARBA00023214};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000248340};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 184..209
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 266..286
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 372..389
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 395..411
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 423..447
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 459..476
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 497..518
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 538..558
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 597..615
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 1..45
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 70..91
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 106..136
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 308..331
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 308..327
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 908 AA; 99217 MW; 2B543624056495F2 CRC64;
MPRSVPQRFP SAPSDIEHVS IETDGRRTSA QTAPPSPSAF RRGHSHLSEA HTGYETLESP
MEVGETTSLL GKGHEHRRNF PRSYTNISGN SGPDLNFRHS LLAGSLRRSR HHSRANSQAM
RFSRRDSDPA ASVAPSAKDD MTASFLDERS WYDQFTSTDW VHDSIADGAR LRELRRRKDI
RGRLLAWFDG SQGWVLVALI GCITAAIAFS VDVTEKFVFD VKEGFCSTHW FHSRQSCCTG
GQECPAWRSW SNILSPSGSE NQWVDYGMFI FWVIFLSVIS CALTLLTKTV VPSSISLTTL
DENLGAASSR GTKGKTGNAS SHDSPSGLQA PGAVIPTRPA MTYYSAAGSG VAEVKVINSG
FVLHGYLGFK TLVVKTVALV FSVASGLSLG KEGPYVHIAT CVGNICCRLF AKYNLNDGKR
REVLSASAAS GVAVAFGAPI GGVLFSLEEV SYYFPPKTLF RTFFCCIAAA LSLKFLNPYG
TGKIVLFQVR YLGDWEMFEM VIFILLGVLG GAAGALFIKA SSVWARSFRR IPIIKRYPML
EVVLVALVTG LVGFWNRYTK LPVSELMFEL ASPCEHVSSS PTGLCPSEDR IGDIIRYLLV
ALVIKSLLTI VTFGIKVPAG IYVPSMVVGG LMGRIVGHVA QYLVLKYPNS FLFGSSCPAV
AGMESCVTPG VYAMVAAGAT MCGVTRLSVT LAVILFELTG SLDHVLPFSL AVLCAKWTAD
AIEPRSIYDL LTDMNAYPFL DNKLQPLSDG QLGDLVRPLR ASRVIDISES SFVPATELRS
KLQNLLMAGE LDSGLPILRH NILTGLIPAP DLEYALDNLE DEENTLCLMT MDVSSAISDS
EDLENTDWVD FTQYIDFSPM SLDIHSPIDL VYQCFAKLGL RYLCVLHNGH YAGLVHKKAF
VKYMKQNE
//
