ID A0A319D4L1_9EURO Unreviewed; 1030 AA.
AC A0A319D4L1;
DT 10-OCT-2018, integrated into UniProtKB/TrEMBL.
DT 10-OCT-2018, sequence version 1.
DT 22-FEB-2023, entry version 18.
DE RecName: Full=Exportin-T {ECO:0000256|ARBA:ARBA00018928, ECO:0000256|RuleBase:RU366037};
DE AltName: Full=Exportin(tRNA) {ECO:0000256|RuleBase:RU366037};
DE AltName: Full=tRNA exportin {ECO:0000256|RuleBase:RU366037};
GN ORFNames=BO71DRAFT_400710 {ECO:0000313|EMBL:PYH92224.1};
OS Aspergillus ellipticus CBS 707.79.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus.
OX NCBI_TaxID=1448320 {ECO:0000313|EMBL:PYH92224.1, ECO:0000313|Proteomes:UP000247810};
RN [1] {ECO:0000313|EMBL:PYH92224.1, ECO:0000313|Proteomes:UP000247810}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 707.79 {ECO:0000313|EMBL:PYH92224.1,
RC ECO:0000313|Proteomes:UP000247810};
RG DOE Joint Genome Institute;
RA Vesth T.C., Nybo J., Theobald S., Brandl J., Frisvad J.C., Nielsen K.F.,
RA Lyhne E.K., Kogle M.E., Kuo A., Riley R., Clum A., Nolan M., Lipzen A.,
RA Salamov A., Henrissat B., Wiebenga A., De vries R.P., Grigoriev I.V.,
RA Mortensen U.H., Andersen M.R., Baker S.E.;
RT "The genomes of Aspergillus section Nigri reveals drivers in fungal
RT speciation.";
RL Submitted (FEB-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: tRNA nucleus export receptor which facilitates tRNA
CC translocation across the nuclear pore complex. Involved in pre-tRNA
CC splicing, probably by affecting the interaction of pre-tRNA with
CC splicing endonuclease. {ECO:0000256|ARBA:ARBA00025147}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496,
CC ECO:0000256|RuleBase:RU366037}. Nucleus
CC {ECO:0000256|RuleBase:RU366037}. Note=Shuttles between the nucleus and
CC the cytoplasm. {ECO:0000256|RuleBase:RU366037}.
CC -!- SIMILARITY: Belongs to the exportin family.
CC {ECO:0000256|ARBA:ARBA00009466, ECO:0000256|RuleBase:RU366037}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; KZ825922; PYH92224.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A319D4L1; -.
DR STRING; 1448320.A0A319D4L1; -.
DR Proteomes; UP000247810; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0031267; F:small GTPase binding; IEA:InterPro.
DR GO; GO:0000049; F:tRNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0008033; P:tRNA processing; IEA:UniProtKB-KW.
DR GO; GO:0071528; P:tRNA re-export from nucleus; IEA:UniProtKB-UniRule.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR013598; Exportin-1/Importin-b-like.
DR InterPro; IPR045546; Exportin-T_C.
DR InterPro; IPR040017; XPOT.
DR PANTHER; PTHR15952:SF11; EXPORTIN-T; 1.
DR PANTHER; PTHR15952; EXPORTIN-T/LOS1; 1.
DR Pfam; PF19282; Exportin-T; 1.
DR Pfam; PF08389; Xpo1; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|RuleBase:RU366037};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|RuleBase:RU366037};
KW Reference proteome {ECO:0000313|Proteomes:UP000247810};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884, ECO:0000256|RuleBase:RU366037};
KW Transport {ECO:0000256|RuleBase:RU366037};
KW tRNA processing {ECO:0000256|ARBA:ARBA00022694};
KW tRNA-binding {ECO:0000256|ARBA:ARBA00022555,
KW ECO:0000256|RuleBase:RU366037}.
FT DOMAIN 102..268
FT /note="Exportin-1/Importin-beta-like"
FT /evidence="ECO:0000259|Pfam:PF08389"
FT DOMAIN 344..1028
FT /note="Exportin-T C-terminal"
FT /evidence="ECO:0000259|Pfam:PF19282"
SQ SEQUENCE 1030 AA; 114918 MW; BB5CDBB349E3541B CRC64;
MEEQVANAIE IAWNPSSDHA LKAQAFDYLN QLRTDPSGWQ VCLALFTKTP QYSEIIRHVA
LEVVNSAAQA GLIDPQALGY VRDGLMTYLR QVYGQENATP DPPNIQNKIA QTITFLFSAL
YGNGWESFFD DLLSLTYKTP ASTGRDNPLG IVFYLRVVNS IHEEIGDVLV SRSRVEQDKA
NLLKDLIRSR DMQKIASSWQ EILSEWRDGN DLVVEMSLKA VGSWVSWIDI GLVVNQTMLD
LLFQQLGRAQ KAELRAGEEK VRDAAVDVFT EIIGKKMKPE DKVDMIIFLN LDTIVTQLSN
SPPLFENRFT FKYDTDLAET VAKLVNITVS DIVRVLEQDI VAPESKEKAT GLLQAFLPHI
LRYFSDEYDE VCSTVIPCVS DLLSYLRKIA KINPALAAQH SSILLPILKA IIAKMRYDET
SSWGDEDDQT DEAEFQELRK RLAVLQQIVA TVNEQLYMEA VSEVVGTTFE NLQQSGAQLD
WRDLDLALHE MFLFGDIAVR AGSLYAKGTP NNQAAERLVA MMLKMVESDI RSFTHPATQL
QYMEICVRYS SFFQYHTHLI PSVLESFLQL VHHPVKKVKT RSWYLFQRLV RQLRSHLGNV
AQTVVEALGD VLVITAEVSS EGSDGDEMSS EDHEGSADAV FNSQLYLYEA VGIICSTPTI
PADKQVIYAQ SVLNPVFMDM EKNLAAAKAN DERALLQIHH DIMALGTLAR GFSDWMPGTS
SPAALPAPEV SEAFMQVSEA TLVALESLKN SFNVRTAARF TFSRLIGVLG SRILPQLPRW
IDGLLTQTSS RDEMALFLRL LDQVIFGFKS EIYTILDALL TPFLQRVFSG IADAPTGTDD
EVQLAELKRE YLNFLLAVLN NELGAVIISE RNQPMFDTVI TTIEHFAKDV EDFTTAKMAF
SVLTKMASSW GGPDIAPEGA NGTAPQQGAL PGFSQFMINR LSPLCWALPA TPTFNSKDAQ
AKQVLMEVGG LQRTIYGKTG MEYIEYLRDR ELPGMGMGAD LVAEFVGALS RLDLKGFRQF
FPSFIQRLSG
//
