ID   A0A319DFB1_9EURO        Unreviewed;       540 AA.
AC   A0A319DFB1;
DT   10-OCT-2018, integrated into UniProtKB/TrEMBL.
DT   10-OCT-2018, sequence version 1.
DT   27-MAR-2024, entry version 16.
DE   RecName: Full=Cation/H+ exchanger domain-containing protein {ECO:0000259|Pfam:PF00999};
GN   ORFNames=BO71DRAFT_444362 {ECO:0000313|EMBL:PYH89753.1};
OS   Aspergillus ellipticus CBS 707.79.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus.
OX   NCBI_TaxID=1448320 {ECO:0000313|EMBL:PYH89753.1, ECO:0000313|Proteomes:UP000247810};
RN   [1] {ECO:0000313|EMBL:PYH89753.1, ECO:0000313|Proteomes:UP000247810}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CBS 707.79 {ECO:0000313|EMBL:PYH89753.1,
RC   ECO:0000313|Proteomes:UP000247810};
RG   DOE Joint Genome Institute;
RA   Vesth T.C., Nybo J., Theobald S., Brandl J., Frisvad J.C., Nielsen K.F.,
RA   Lyhne E.K., Kogle M.E., Kuo A., Riley R., Clum A., Nolan M., Lipzen A.,
RA   Salamov A., Henrissat B., Wiebenga A., De vries R.P., Grigoriev I.V.,
RA   Mortensen U.H., Andersen M.R., Baker S.E.;
RT   "The genomes of Aspergillus section Nigri reveals drivers in fungal
RT   speciation.";
RL   Submitted (FEB-2018) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; KZ826013; PYH89753.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A319DFB1; -.
DR   STRING; 1448320.A0A319DFB1; -.
DR   Proteomes; UP000247810; Unassembled WGS sequence.
DR   GO; GO:0005886; C:plasma membrane; IEA:InterPro.
DR   GO; GO:0015385; F:sodium:proton antiporter activity; IEA:InterPro.
DR   GO; GO:0120029; P:proton export across plasma membrane; IEA:InterPro.
DR   GO; GO:0042391; P:regulation of membrane potential; IEA:InterPro.
DR   GO; GO:0036376; P:sodium ion export across plasma membrane; IEA:InterPro.
DR   Gene3D; 1.20.1530.20; -; 1.
DR   InterPro; IPR006153; Cation/H_exchanger.
DR   InterPro; IPR004712; Na+/H+_antiporter_fungi.
DR   InterPro; IPR038770; Na+/solute_symporter_sf.
DR   PANTHER; PTHR31382; NA(+)/H(+) ANTIPORTER; 1.
DR   PANTHER; PTHR31382:SF1; SODIUM ION_PROTON EXCHANGER (EUROFUNG); 1.
DR   Pfam; PF00999; Na_H_Exchanger; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000247810};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        6..28
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        35..53
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        105..128
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        182..198
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        219..237
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        257..289
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        310..329
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        335..351
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        372..391
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        418..438
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          20..436
FT                   /note="Cation/H+ exchanger"
FT                   /evidence="ECO:0000259|Pfam:PF00999"
FT   REGION          492..540
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   540 AA;  59861 MW;  545F9BE1B51C397F CRC64;
     MPTLSLINFN IVCATLGGFI SIFGLVSYLF KERFYLSEAL ISLLAGVIFS PHAANFIRPQ
     EYALGSEQNL EEITLYFTRL VLGVQLVLAG VQLPKRYLQI EWRSLSLLLG PGMAAMWMCS
     SLIIWAMVPN FPFLHALIVG ACITPTDPVL SNSIVKGKFA DKNVPRPLQR IIVAESGAND
     GLGYPFLFFG MYLLKYVSMG GEGYSGGAGK AMALWFYETW VYTIIVSVVY GITVGWVSRE
     LLHWAEEKRY VDRESFLVFA IALALFLVGT CGMLGTDDLL ACFIAGNVFT QDDWFRLETM
     DDSLQPTMDM LLNLAVFMWF GAVCPWPSFL DNNVIPIYRL IFLGILILLV RRMPIIFAMH
     KYISQIEQVQ QAAFVGFFGP IGVGAVFYLS VSREFLLQIT VDGKVREDAQ QVSEAVDVIV
     WFLVVCSIVV HGLSIPLAKA GYHIPRTISQ ALSTTTTMES DHVSIGNNWH THSTATRSIG
     LANNRNRRRI NAREAPESPV SQVHVGSGDP EEPARPVNLV IRDEAVENAP ESPSPPAACH
//