ID   A0A319DFB9_9EURO        Unreviewed;       806 AA.
AC   A0A319DFB9;
DT   10-OCT-2018, integrated into UniProtKB/TrEMBL.
DT   10-OCT-2018, sequence version 1.
DT   27-MAR-2024, entry version 15.
DE   SubName: Full=Vacuolar transporter chaperone 4 {ECO:0000313|EMBL:PYH96046.1};
GN   ORFNames=BO71DRAFT_349936 {ECO:0000313|EMBL:PYH96046.1};
OS   Aspergillus ellipticus CBS 707.79.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus.
OX   NCBI_TaxID=1448320 {ECO:0000313|EMBL:PYH96046.1, ECO:0000313|Proteomes:UP000247810};
RN   [1] {ECO:0000313|EMBL:PYH96046.1, ECO:0000313|Proteomes:UP000247810}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CBS 707.79 {ECO:0000313|EMBL:PYH96046.1,
RC   ECO:0000313|Proteomes:UP000247810};
RG   DOE Joint Genome Institute;
RA   Vesth T.C., Nybo J., Theobald S., Brandl J., Frisvad J.C., Nielsen K.F.,
RA   Lyhne E.K., Kogle M.E., Kuo A., Riley R., Clum A., Nolan M., Lipzen A.,
RA   Salamov A., Henrissat B., Wiebenga A., De vries R.P., Grigoriev I.V.,
RA   Mortensen U.H., Andersen M.R., Baker S.E.;
RT   "The genomes of Aspergillus section Nigri reveals drivers in fungal
RT   speciation.";
RL   Submitted (FEB-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}. Vacuole membrane
CC       {ECO:0000256|ARBA:ARBA00004128}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004128}.
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DR   EMBL; KZ825843; PYH96046.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A319DFB9; -.
DR   STRING; 1448320.A0A319DFB9; -.
DR   Proteomes; UP000247810; Unassembled WGS sequence.
DR   GO; GO:0005774; C:vacuolar membrane; IEA:UniProtKB-SubCell.
DR   CDD; cd07751; PolyPPase_VTC4_like; 1.
DR   CDD; cd14480; SPX_VTC2_like; 1.
DR   Gene3D; 3.20.100.30; VTC, catalytic tunnel domain; 1.
DR   InterPro; IPR003807; DUF202.
DR   InterPro; IPR004331; SPX_dom.
DR   InterPro; IPR018966; VTC_domain.
DR   InterPro; IPR042267; VTC_sf.
DR   PANTHER; PTHR46140; VACUOLAR TRANSPORTER CHAPERONE 1-RELATED; 1.
DR   PANTHER; PTHR46140:SF1; VACUOLAR TRANSPORTER CHAPERONE 4; 1.
DR   Pfam; PF02656; DUF202; 1.
DR   Pfam; PF09359; VTC; 1.
DR   PROSITE; PS51382; SPX; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000247810};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}; Vacuole {ECO:0000256|ARBA:ARBA00022554}.
FT   TRANSMEM        695..715
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        722..744
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        764..783
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          1..172
FT                   /note="SPX"
FT                   /evidence="ECO:0000259|PROSITE:PS51382"
FT   REGION          101..120
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          514..547
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          343..370
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        101..117
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   806 AA;  92670 MW;  D74FEF29F7A11BA5 CRC64;
     MRFGEHLRSS MIKEYYWYYI AYEDLKKALK TGYIAEPTPE NARPDRQPWS EDDEKHFVTL
     LESELDKVFN FQRIKSAEIA RRIQSSEVEV TDVVSRLENS SVSRSDNASN TRSSRAPPSD
     EDFLMLEQSL SDIIADVHDL AKFTQLNYTG FQKIIKKHDK ETGWHLKPVF AARLNAKPFF
     NDNYDALVVR LSKLYDLVRT KGNPVKGDSS AGGTQQNFVR QTTKYWVHPD NITELKLIIL
     KHLPVLVFNS RKEFEEKDSA ISSIYYDNTD TWELYQGRLK KTEGAEAIRL RWYGGMESDQ
     IFVERKTHRE DWTGEKSVKA RFALKEKHVN AYLSGRMTVE SIFEKMRREG KKSEEEINSL
     EQLAQEIQYR IISRKLVPVN RSFYHRTAFQ LPGDARVRIS LDTELTMVRE DNLDGRQRAG
     NNWRRMDIGV DYPFSQLPAE DVERFPYAVL EVKLQTQAGQ EPPQWIRDLT ASHLVEAVPK
     YSKFIHGTAT LMSDRINLLP FWMPQMDVDI RKPATRKFGI QRPPASTTLS TTETPEDDES
     DDEDSNEARW AEGVNRAQAA NQEALFADPD GNELDVEERI AAMPLPGDED YPLYDSDAES
     VDSDELEEAR RVGGTYYYKK LAKSYFHQAG HAMVNGLLTL VPRPRPTNMP SPEQNGIAVM
     GNKRTVKRFH APKGKRIYVP VRVEPKVYFA AERTFLSWLE FSILLGTIAA TLLNFGEDYI
     TLASSWAFTI LAAVALVYSL MLYIWRVDKI RKRRDVRRVY YEKWGPTVVG LGLVAIVMVN
     FGLRARQANF LARDGDLFDP PHGGDL
//