ID   A0A319DSF3_9EURO        Unreviewed;      1568 AA.
AC   A0A319DSF3;
DT   10-OCT-2018, integrated into UniProtKB/TrEMBL.
DT   10-OCT-2018, sequence version 1.
DT   08-NOV-2023, entry version 14.
DE   SubName: Full=GTPase activating protein {ECO:0000313|EMBL:PYH94233.1};
GN   ORFNames=BO71DRAFT_483912 {ECO:0000313|EMBL:PYH94233.1};
OS   Aspergillus ellipticus CBS 707.79.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus.
OX   NCBI_TaxID=1448320 {ECO:0000313|EMBL:PYH94233.1, ECO:0000313|Proteomes:UP000247810};
RN   [1] {ECO:0000313|EMBL:PYH94233.1, ECO:0000313|Proteomes:UP000247810}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CBS 707.79 {ECO:0000313|EMBL:PYH94233.1,
RC   ECO:0000313|Proteomes:UP000247810};
RG   DOE Joint Genome Institute;
RA   Vesth T.C., Nybo J., Theobald S., Brandl J., Frisvad J.C., Nielsen K.F.,
RA   Lyhne E.K., Kogle M.E., Kuo A., Riley R., Clum A., Nolan M., Lipzen A.,
RA   Salamov A., Henrissat B., Wiebenga A., De vries R.P., Grigoriev I.V.,
RA   Mortensen U.H., Andersen M.R., Baker S.E.;
RT   "The genomes of Aspergillus section Nigri reveals drivers in fungal
RT   speciation.";
RL   Submitted (FEB-2018) to the EMBL/GenBank/DDBJ databases.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; KZ825875; PYH94233.1; -; Genomic_DNA.
DR   STRING; 1448320.A0A319DSF3; -.
DR   Proteomes; UP000247810; Unassembled WGS sequence.
DR   GO; GO:0005634; C:nucleus; IEA:InterPro.
DR   GO; GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
DR   GO; GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro.
DR   Gene3D; 3.40.50.11210; Rap/Ran-GAP; 1.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR035974; Rap/Ran-GAP_sf.
DR   InterPro; IPR000331; Rap/Ran_GAP_dom.
DR   InterPro; IPR018515; Tuberin-type_domain.
DR   InterPro; IPR027107; Tuberin/Ral-act_asu.
DR   InterPro; IPR024584; Tuberin_N.
DR   PANTHER; PTHR10063; TUBERIN; 1.
DR   PANTHER; PTHR10063:SF0; TUBERIN; 1.
DR   Pfam; PF11864; DUF3384; 1.
DR   Pfam; PF02145; Rap_GAP; 1.
DR   Pfam; PF03542; Tuberin; 1.
DR   SUPFAM; SSF48371; ARM repeat; 1.
DR   SUPFAM; SSF111347; Rap/Ran-GAP; 1.
DR   PROSITE; PS50085; RAPGAP; 1.
PE   4: Predicted;
KW   GTPase activation {ECO:0000256|ARBA:ARBA00022468};
KW   Reference proteome {ECO:0000313|Proteomes:UP000247810}.
FT   DOMAIN          1270..1507
FT                   /note="Rap-GAP"
FT                   /evidence="ECO:0000259|PROSITE:PS50085"
FT   REGION          31..54
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          445..466
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          747..793
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1060..1080
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1504..1535
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        747..779
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1568 AA;  174768 MW;  9325203C66318B10 CRC64;
     MSSDDAPSPY HTKNTASSFV DVIRSLGVSR PKSLSPVSLQ DSSDSLSQST DGRRSSRIVL
     GFESMHRGSV VSSSSDTSGA RDFDTAVRTL AQRQSLGHAI DEAEQISKSL QCFTPEQSLA
     LWEAATYLLH HESSPEARRS GSMLLEAVAA RQDLSPAARR IVFDSISNSS DNDVIPARIQ
     SLIALSDHGR KLDFATSSVL PVISTCLVPL YELISSARLK ARKSKVGKTN GLGYDGAVLD
     DLLQFAVDLI TLQRKPPSSE EVEMLLEQIF IICRKTSVAA DIKNSLSVFD ALILYSDVPD
     GSFIPMLEVL CSIHSSVKSL SGPTSRAVRN LAKSRRQLEM AENLYTFLSE SCGEKSRNLN
     VVRGTVYVFM DLVRAHGQDG MPELQFDRLI DCLRILVMNK DDGRLEADVL ELCLNILEGD
     FVHVALEKNW KELVNVMNSC SLRAVDEPDE SSPTTPDSQP LLPRGSVLDD TRSNILANVI
     QIASTLETLW DRLNHQQRLE STRFLMNACR YIEPPQAELV LDTIRMESFC SPENPGWIQE
     CQRIIRYFIR SRNKPSDIRI LALDGLKDAF TTYDSLVLFQ EEGLLNLMLE KFADEDDILF
     LESLVSFLVD TSVLASDDDT FKRLVDILSS PMNKDLDKEG VLGSESSTLS SERHSYDSVL
     ELSLANVCTI GLVRMFLRTL NMSANKAASA YEALLMIAQS SDRPVDARLT SLKLLFRLRC
     DSSGSITVTS VSESDFMMNI SGRNFETGSK SHEDYAGDHD NDSDQGRPTT HRRHSTREPS
     ASMLSRSTGR NSSIPIRAAK LTPPIWTFAA PQVLPEAPPD ESSPFVYAYA TPDTSHHLES
     DPAQKVALKA NMWLETVISL LQRETNWDLY SYVLAHLATQ LQNKDLFSNA VPQVKLLRSI
     LCDQVKNDSF REPPATTGVK KTDVAGYIFE FLCALISYHE HFAKSEEDEL VRAFMMGIIG
     SWGGTSRGCI HALSVCCHEI PLSVTKSLNG ILDKMSKVIT LSNLAVHILE FLALLARLPD
     VYVNLREEEI RTVFGICVRF LQTSREHRFR VSESPTRSAH VSTRLGRESL ASPADSSDPS
     LQDGMSRYIY TLTYHVMIFW FLSLKLQDRA KHVNWITSRL IYMDEHEKET VEEPSQVFID
     LMQRAAFSDL GDTIPYPTFP PTPEDGPVVR KSWIVGMSIV TVETAGVSGL TQITKRQASG
     TTYATFQQRT APVLPHQVPP TPDAHLHSDT LRTAVLPSHI MLQLTTTAFP TPTVMQPIPL
     PEDDVTRRAL NTFDRNDIVD GHKIGVVYID NGQTTEAEIL SNTNGSADYE YFLSRLGTKV
     PLQGARFNTQ GLHADFDGES TYAWRDRVTE IVYHVATMMP TNFDNDPSCV NKKRHIGNDF
     VNIVFNRSNT PFNFNTVPSQ FNFVNIVITP VCRITNDPGS TEPRPTDFEK RFYQVRVMSK
     PGFPEISPAA APKIISGKNL AAFVRILALN ASVFSLVWHS QGGEHISSWR NRLREIKRLR
     ERALGSQAQS SEAAEGTYPT QRRNTKANIF SEEVPSRNAS VQTDFTTDWN AAADAHILEN
     LDFSRWGR
//