ID   A0A319EWY9_ASPSB        Unreviewed;       544 AA.
AC   A0A319EWY9;
DT   10-OCT-2018, integrated into UniProtKB/TrEMBL.
DT   10-OCT-2018, sequence version 1.
DT   28-JUN-2023, entry version 16.
DE   RecName: Full=Pre-mRNA-splicing factor {ECO:0000256|RuleBase:RU369096};
GN   ORFNames=BO78DRAFT_461101 {ECO:0000313|EMBL:PYI06599.1};
OS   Aspergillus sclerotiicarbonarius (strain CBS 121057 / IBT 28362).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus.
OX   NCBI_TaxID=1448318 {ECO:0000313|EMBL:PYI06599.1, ECO:0000313|Proteomes:UP000248423};
RN   [1] {ECO:0000313|EMBL:PYI06599.1, ECO:0000313|Proteomes:UP000248423}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CBS 121057 {ECO:0000313|EMBL:PYI06599.1,
RC   ECO:0000313|Proteomes:UP000248423};
RG   DOE Joint Genome Institute;
RA   Vesth T.C., Nybo J., Theobald S., Brandl J., Frisvad J.C., Nielsen K.F.,
RA   Lyhne E.K., Kogle M.E., Kuo A., Riley R., Clum A., Nolan M., Lipzen A.,
RA   Salamov A., Henrissat B., Wiebenga A., De vries R.P., Grigoriev I.V.,
RA   Mortensen U.H., Andersen M.R., Baker S.E.;
RT   "The genomes of Aspergillus section Nigri reveals drivers in fungal
RT   speciation.";
RL   Submitted (FEB-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Involved in spliceosome maturation and the first step of pre-
CC       mRNA splicing. {ECO:0000256|RuleBase:RU369096}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC       ECO:0000256|RuleBase:RU369096}.
CC   -!- SIMILARITY: Belongs to the SPP2 family. {ECO:0000256|ARBA:ARBA00008576,
CC       ECO:0000256|RuleBase:RU369096}.
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DR   EMBL; KZ826348; PYI06599.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A319EWY9; -.
DR   STRING; 1448318.A0A319EWY9; -.
DR   Proteomes; UP000248423; Unassembled WGS sequence.
DR   GO; GO:0005681; C:spliceosomal complex; IEA:UniProtKB-UniRule.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; IEA:UniProtKB-UniRule.
DR   InterPro; IPR000467; G_patch_dom.
DR   InterPro; IPR045166; Spp2-like.
DR   InterPro; IPR026822; Spp2/MOS2_G-patch.
DR   PANTHER; PTHR15818; G PATCH AND KOW-CONTAINING; 1.
DR   PANTHER; PTHR15818:SF2; G-PATCH DOMAIN AND KOW MOTIFS-CONTAINING PROTEIN; 1.
DR   Pfam; PF12656; G-patch_2; 1.
DR   PROSITE; PS50174; G_PATCH; 1.
PE   3: Inferred from homology;
KW   mRNA processing {ECO:0000256|RuleBase:RU369096};
KW   mRNA splicing {ECO:0000256|RuleBase:RU369096};
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|RuleBase:RU369096};
KW   Reference proteome {ECO:0000313|Proteomes:UP000248423};
KW   Spliceosome {ECO:0000256|RuleBase:RU369096}.
FT   DOMAIN          274..299
FT                   /note="G-patch"
FT                   /evidence="ECO:0000259|PROSITE:PS50174"
FT   REGION          1..135
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          170..204
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          216..264
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          296..544
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..61
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        62..85
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        219..255
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        374..544
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   544 AA;  61662 MW;  31AF42050EE49724 CRC64;
     MSSSQPPQNG NADSQGKSSA KPFSLSLGGG NSTTTTPTAN GQPKKTAFNL QGSTRSTDSS
     NRTLAHRPHH LHDDEDSDEE APPAHEAVTG FDTLTGTAIP ANKPAEKREL VIPVAGNNNW
     RDRPGVNNRK PKGKNLLPKE VQAIQEAQKR GEIAGDNVET ERASMAYGLS FAQPDSEQVE
     RDNDRPMQDA PEPAAPDVVK ERKPLTQDEI ALQALIRETN GEPERRSDLV IESAHRDDGD
     DRVSGRYDET TSFRADMASR PESASLDQYN AIPVEEFGAA LLRGMGWKEG QAVGRGKYGG
     ASGNQDNKPR VPERRPGFLG IGAKDASGGK GAEAELGAWG KAAMRKGSRK SGKEGDSNTE
     GVYMPIMMRN TKTGEFITEE ELAVQRKEAK KRGDDDEWKE RRDRNLEKSG RDRDRDRDRD
     RDRDSRRRDY DDDESDRYDR RRTGSSRRDR SLSSSDRQSR RRRYGDEDSD SRDDRYYRDR
     NGDRERERDR DKDRDRDRSR RYRDDDRHSS SRHSSSHTSS RHRDRDRERD SDRDSYRRRR
     DDDR
//