ID A0A323V152_9RHOO Unreviewed; 1871 AA.
AC A0A323V152;
DT 10-OCT-2018, integrated into UniProtKB/TrEMBL.
DT 10-OCT-2018, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE RecName: Full=UvrABC system protein A {ECO:0000256|ARBA:ARBA00039316};
DE AltName: Full=Excinuclease ABC subunit A {ECO:0000256|ARBA:ARBA00042156};
GN Name=uvrA {ECO:0000313|EMBL:PZA17700.1};
GN ORFNames=DNK49_03995 {ECO:0000313|EMBL:PZA17700.1};
OS Parazoarcus communis SWub3 = DSM 12120.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales; Zoogloeaceae;
OC Parazoarcus.
OX NCBI_TaxID=1121029 {ECO:0000313|EMBL:PZA17700.1, ECO:0000313|Proteomes:UP000248259};
RN [1] {ECO:0000313|EMBL:PZA17700.1, ECO:0000313|Proteomes:UP000248259}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SWub3 {ECO:0000313|EMBL:PZA17700.1,
RC ECO:0000313|Proteomes:UP000248259};
RA Zorraquino Salvo V., Toubiana D., Blumwald E.;
RT "Azoarcus communis strain SWub3 genome.";
RL Submitted (JUN-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- SIMILARITY: Belongs to the ABC transporter superfamily. UvrA family.
CC {ECO:0000256|ARBA:ARBA00038000}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PZA17700.1}.
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DR EMBL; QKOE01000002; PZA17700.1; -; Genomic_DNA.
DR OrthoDB; 9809851at2; -.
DR Proteomes; UP000248259; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0009380; C:excinuclease repair complex; IEA:InterPro.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0004518; F:nuclease activity; IEA:UniProtKB-KW.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0006289; P:nucleotide-excision repair; IEA:InterPro.
DR GO; GO:0009432; P:SOS response; IEA:UniProtKB-KW.
DR Gene3D; 3.30.190.20; -; 1.
DR Gene3D; 1.10.8.280; ABC transporter ATPase domain-like; 1.
DR Gene3D; 1.20.1580.10; ABC transporter ATPase like domain; 3.
DR Gene3D; 3.30.1490.20; ATP-grasp fold, A domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 5.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR017871; ABC_transporter-like_CS.
DR InterPro; IPR013815; ATP_grasp_subdomain_1.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR004602; UvrA.
DR InterPro; IPR041552; UvrA_DNA-bd.
DR InterPro; IPR041102; UvrA_inter.
DR InterPro; IPR001510; Znf_PARP.
DR NCBIfam; TIGR00630; uvra; 1.
DR PANTHER; PTHR43152; UVRABC SYSTEM PROTEIN A; 1.
DR PANTHER; PTHR43152:SF3; UVRABC SYSTEM PROTEIN A; 1.
DR Pfam; PF17755; UvrA_DNA-bind; 1.
DR Pfam; PF17760; UvrA_inter; 1.
DR SMART; SM00382; AAA; 3.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 4.
DR PROSITE; PS00211; ABC_TRANSPORTER_1; 2.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 1.
DR PROSITE; PS50064; ZF_PARP_2; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW DNA excision {ECO:0000256|ARBA:ARBA00022769};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Excision nuclease {ECO:0000256|ARBA:ARBA00022881};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000248259};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW SOS response {ECO:0000256|ARBA:ARBA00023236};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT DOMAIN 117..140
FT /note="PARP-type"
FT /evidence="ECO:0000259|PROSITE:PS50064"
FT DOMAIN 1189..1480
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
SQ SEQUENCE 1871 AA; 204434 MW; 5BABA15C23B95719 CRC64;
MSEADPRSTP DAIRIRGARQ NNLRNLSLDL PLNQLTVVTG VSGSGKSSLV FDTLYAEGQR
RYVETFSPYA RQFLDRMDKP QVDRIEGVPP AIAIDQTSQV RTSRSTVGTM TELADHFKLL
YARAARLHCR SCGEPVRRDS TDSIAADLQQ RCAAAGDPRL VICFAVTIPK AYTEAEVTAL
LNVQGYTRIH RRDEGSDGDV LQVVQDRFRL SSAEPSRLAE ALEAALRLGH GRLTVFASGD
GVVQGEVAWR YSDGLHCADC DIHYNDPSPG LFSFNSAIGA CETCRGFGRV IGVDFGLVVP
DESKTLAEGA IKPWQTESYK ECQQDLAKMA KKAGVAMDIP FRDLPPEHRR WVLEGDEKWK
NWDSSWPRYW YGVRHFFAWL ETKAYKMHIR VLLSRYRSYT ECPACHGARL KPEALLWRLP
MQDGPGLAIH QLMALPVDRI RQAVDALVFP GIADEATELV LGEIRSRLTY LADVGLGYLT
LDRQSRTLSG GEVQRINLTT ALGTSLVNTL FVLDEPSIGL HPRDIGRILG VMTRLRDAGN
TLVVVEHDPQ VMVAADELLE IGPGPGERGG NIVARGTPAE ITANPDSITG PWLAGSKRID
VQRPPRPVCD DTPRLRLVGA CEHNLRNLTV DFPLGRMTCL TGVSGSGKST LIQDVLYPAL
AKHFGEAVET PGAFERLEGV DKLRGVVMVD QSAIGKSSRS NPVSYVGAWD SIRNLYAALP
QAKERGYSPG TFSFNSGHGR CPTCTGSGFE HVEMQFLSDV WLRCPDCDGK RYRPEILELQ
WRGKSVADVL DMTVREALQF FDDQPKVLAA LAPLADVGLD YLRLGQPVPT LSGGEAQRLK
LAGHLAEAAQ KKSARKVRPV DNLVEKFVDK VEPGLLFLFD EPTTGLHFED VATLLGAFDK
LLQAGHSLIV IEHNLDVIAA ADWIIDLGPE GGEAGGQIVA EGPVDVLRAH RLSHTAAALR
DYAEALARTR AAPLILAEPA VAYRTLAAPE IEIRHAREHN LKNISVSIPR DRFTVVTGLS
GSGKSTLAFD IVFGEGQRRY LESLNAYARQ FVQPASRPDV DGLFGIPPTV AIEQRTSRGG
RKSTVATLTE IHPFLRLMYV KLGTQYCPDC NVPVTPQSFE AIVGQILREH RDTSVEVLAP
LVSNRKGLYT DLAKWARGKG HTQLRVDGEY LPTAKWPRLD RYKEHTIELP VGMVVVQPAS
ETTLREFVQV ALEHGKGVLK VLELGKLGAQ PVTFSTLRAC PDCGTGFPEP DPRLFSYNAK
HGWCPKCYGT GLKTTSRIED PDALDLGDAE EMVSEDEACP ACEGARLNPV ARAVRFRDRG
LHQLAALPVD KAAGFFSELE LNARETDIAR DLISEIRGRL DFLRHVGLGY LALDRAAPTL
SGGEAQRIRL AAQLGSNLRG VCYILDEPTI GLHPRDNRLL LDTLEALRDR GNTLLVVEHD
EDTIRRADHV IDLGPGAGVR GGRVVAEGDV AALLAAPESA TGACFRQPLQ HPMRPRREVA
ERHPAIRVEG ADLHNLSDVT VQIPLARLTV VTGVSGSGKS SLARDVIHAN LRARLGDPEA
TRARRRGQAQ PDEVDQPLVG CRALQGWQQV GRVLEVDQTP IGKTPRSCPA TYVGFWDAIR
KLFADTFDAR TRGWNASRFS FNTGAGRCPV CDGAGQTTVE MNFLPDVKTP CEACGGARFN
PETLSVRWRD KTVAEVLAMP VDEAVGFFAA HPAIAHPLQL LQDVGLGYLT LGQPSPTLSG
GEAQRIKLVT ELAKVRRRPG EASDTGGVPL PADKHSLYVL DEPTVGLHMA DVDKLIHVLH
RLTDAGHTVL VIEHDLDVMA EADWLIDLGP EGGDGGGRVV AEGPPEVAMA IPASHTGRHL
REFLDLRRGG D
//
