ID A0A323V910_9ACTN Unreviewed; 426 AA.
AC A0A323V910;
DT 10-OCT-2018, integrated into UniProtKB/TrEMBL.
DT 10-OCT-2018, sequence version 1.
DT 27-MAR-2024, entry version 16.
DE SubName: Full=MFS family permease {ECO:0000313|EMBL:MBB3678304.1};
DE SubName: Full=MFS transporter {ECO:0000313|EMBL:PZA20570.1};
GN ORFNames=DMO24_14780 {ECO:0000313|EMBL:PZA20570.1}, FHX36_004093
GN {ECO:0000313|EMBL:MBB3678304.1};
OS Modestobacter versicolor.
OC Bacteria; Actinomycetota; Actinomycetes; Geodermatophilales;
OC Geodermatophilaceae; Modestobacter.
OX NCBI_TaxID=429133 {ECO:0000313|EMBL:PZA20570.1, ECO:0000313|Proteomes:UP000247602};
RN [1] {ECO:0000313|EMBL:PZA20570.1, ECO:0000313|Proteomes:UP000247602}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CP153-2 {ECO:0000313|EMBL:PZA20570.1,
RC ECO:0000313|Proteomes:UP000247602};
RA Gundlapally S.R.;
RT "Draft genome sequence of Modestobacter versicolor CP153-2.";
RL Submitted (JUN-2018) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:MBB3678304.1, ECO:0000313|Proteomes:UP000580718}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 16678 {ECO:0000313|EMBL:MBB3678304.1,
RC ECO:0000313|Proteomes:UP000580718};
RA Klenk H.-P.;
RT "Sequencing the genomes of 1000 actinobacteria strains.";
RL Submitted (AUG-2020) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane
CC {ECO:0000256|ARBA:ARBA00004429}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004429}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PZA20570.1}.
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DR EMBL; JACIBU010000002; MBB3678304.1; -; Genomic_DNA.
DR EMBL; QKNV01000166; PZA20570.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A323V910; -.
DR OrthoDB; 9815525at2; -.
DR Proteomes; UP000247602; Unassembled WGS sequence.
DR Proteomes; UP000580718; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR CDD; cd06173; MFS_MefA_like; 1.
DR Gene3D; 1.20.1250.20; MFS general substrate transporter like domains; 1.
DR InterPro; IPR020846; MFS_dom.
DR InterPro; IPR036259; MFS_trans_sf.
DR InterPro; IPR010290; TM_effector.
DR PANTHER; PTHR23513; INTEGRAL MEMBRANE EFFLUX PROTEIN-RELATED; 1.
DR PANTHER; PTHR23513:SF6; MULTIDRUG EFFLUX PUMP TAP; 1.
DR Pfam; PF05977; MFS_3; 1.
DR SUPFAM; SSF103473; MFS general substrate transporter; 1.
DR PROSITE; PS50850; MFS; 1.
PE 4: Predicted;
KW Antibiotic resistance {ECO:0000256|ARBA:ARBA00023251};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000247602};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 21..41
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 47..67
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 79..100
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 106..126
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 226..249
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 261..280
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 289..307
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 313..333
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 354..372
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 378..398
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 173..426
FT /note="Major facilitator superfamily (MFS) profile"
FT /evidence="ECO:0000259|PROSITE:PS50850"
SQ SEQUENCE 426 AA; 44741 MW; 2A2C97741406B45A CRC64;
MTADRSLLRH RDFRHLWAAE TVSQVGTQVT MLALPVVAVT LLDATPWQMG VLTALETAAF
LLIGLPAGAW VDRWRRKRVL VVADLVRAVV LGTLPLAYLL DVLTLGQLFV VAAVTGTATV
FFDVAYQSYL PALVDRDQLV DGNGKLEASR AVAQVAGPGL TGVLLRLVGA PVLVLVDAAS
FLLSALFLGS IRQPDTVPDR ADRRPLRTEI GEGLSFVVRH PLLRRIVACT GTANLFGSMT
NALLVLYVIR ELGLSEATLG LVFSVGAVGG LLGAGTAAWY TRRVGEGRAI PLSAVVFAAA
GTSLPLAAVG APVVWLVTGW FVLSWSTVVY NVTQVSFRQR LCPPRLLGRM NASVRFIVYG
SMPLGGLAGG VLGEWLGVVP ALWVAAAGGF AACLPVVLSP LLTMGDLPDE LDATTGPAPV
APADAG
//
