ID A0A327QMA5_9BACT Unreviewed; 1436 AA.
AC A0A327QMA5;
DT 10-OCT-2018, integrated into UniProtKB/TrEMBL.
DT 10-OCT-2018, sequence version 1.
DT 27-MAR-2024, entry version 14.
DE SubName: Full=Cobalt-zinc-cadmium resistance protein CzcA {ECO:0000313|EMBL:RAJ05391.1};
GN ORFNames=LX64_02549 {ECO:0000313|EMBL:RAJ05391.1};
OS Chitinophaga skermanii.
OC Bacteria; Bacteroidota; Chitinophagia; Chitinophagales; Chitinophagaceae;
OC Chitinophaga.
OX NCBI_TaxID=331697 {ECO:0000313|EMBL:RAJ05391.1, ECO:0000313|Proteomes:UP000249547};
RN [1] {ECO:0000313|EMBL:RAJ05391.1, ECO:0000313|Proteomes:UP000249547}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 23857 {ECO:0000313|EMBL:RAJ05391.1,
RC ECO:0000313|Proteomes:UP000249547};
RA Goeker M.;
RT "Genomic Encyclopedia of Archaeal and Bacterial Type Strains, Phase II
RT (KMG-II): from individual species to whole genera.";
RL Submitted (JUN-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the outer membrane factor (OMF) (TC 1.B.17)
CC family. {ECO:0000256|ARBA:ARBA00007613}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RAJ05391.1}.
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DR EMBL; QLLL01000004; RAJ05391.1; -; Genomic_DNA.
DR OrthoDB; 9758757at2; -.
DR Proteomes; UP000249547; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015562; F:efflux transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0008324; F:monoatomic cation transmembrane transporter activity; IEA:InterPro.
DR Gene3D; 3.30.70.1430; Multidrug efflux transporter AcrB pore domain; 2.
DR Gene3D; 3.30.70.1440; Multidrug efflux transporter AcrB pore domain; 1.
DR Gene3D; 3.30.70.1320; Multidrug efflux transporter AcrB pore domain like; 1.
DR Gene3D; 1.20.1640.10; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR Gene3D; 1.20.1600.10; Outer membrane efflux proteins (OEP); 1.
DR InterPro; IPR027463; AcrB_DN_DC_subdom.
DR InterPro; IPR001036; Acrflvin-R.
DR InterPro; IPR004763; CusA-like.
DR InterPro; IPR003423; OMP_efflux.
DR NCBIfam; TIGR00914; 2A0601; 1.
DR PANTHER; PTHR32063; -; 1.
DR PANTHER; PTHR32063:SF24; CATION EFFLUX SYSTEM (ACRB_ACRD_ACRF FAMILY); 1.
DR Pfam; PF00873; ACR_tran; 1.
DR Pfam; PF02321; OEP; 2.
DR PRINTS; PR00702; ACRIFLAVINRP.
DR SUPFAM; SSF82866; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR SUPFAM; SSF56954; Outer membrane efflux proteins (OEP); 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000249547};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..29
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 341..360
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 367..387
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 393..416
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 448..468
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 480..503
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 538..554
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 873..892
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 899..918
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 924..949
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 970..991
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1003..1028
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1040..1058
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 1436 AA; 157972 MW; 45B50248E41CD0D5 CRC64;
MLNKIIQFSI RYKLVIALMT VALIIWGLWS ASRLPVDAVP DITNNQVQII TVTPTLAAQE
TEQLVTYPIE QSLANLPDLE EMRSISRFGL SVITVVFDDK VDIYFARQLI NEKLKEAEEK
IPAGIGKPEL APVSTGLGEV YQYVIHPKKG AENKYSAMDL RTMQDWIVAR QLYGTKGVAE
VNSFGGLLKQ YEVALNPARL NALNVTIPEI FTALEKNNSN TGGAYIDKKP NAYFIRGIGL
VGNMNDINKI VIKNINGIPV LIRDVAEVRL GNAVRYGAVT YNGEKEVVGG IVMMLKGSNS
AAVVKRVKEK METIKRSLPE DVIIEPFLDR TSLVDRAVNT VKTNLVEGAL IVIFVLVVFL
GNLRAGLIVA SAIPLAMLFA LGMMHTFGVS ANLMSLGAID FGLIVDGAVI IVEATLHHLG
LRKSTHRLTQ AEMDEEVFLS ASKIRNSAAF GEIIILIVYI PILTLVGIEG KMFRPMAQTV
GFAILGALIL SLTYIPMMSA LFLPKQLKQT PTFSDRMMHF LHRKYAPVLN WAIRTRKAII
IATVAVFGVT IILFKNMGGE FIPQLEEGDF AFHCILPQGT SLSQSIETSM QASRLIREFP
EVKMVVGKTG SAEVPTDPMP PEASDLIIVL KPKKEWTTTK SYDELANKIL DRLSTIPGVF
FEANQPIQMR FNELMTGVRQ DVAIKVFGEN IDTLAAIAPK ISTIIQSVKG ATAPQIERTT
GLPQITITYD RDRIAGYGMN IDDINRTIST AFAGEAAGVV FENERKFDLV VRLDSAHRAS
IDDVNNLFVT TPSGLQVPLS QVATVSFKEG PSQISREEGK RRIVVGFNVK DRDVQSVVKD
IQEKLSTANI LPGGYYYTVG GTFENLQEAS TRLQIAVPVA LGLIFVLLYF TFNSLKESLL
IFTAIPMSAI GGVLALLLRG MPFSISAGVG FIALFGVAVL NGIVLISTFN QLQKEGIQDV
IERVKEGTRI RLRPVLMTAT VASFGFIPMA LSTGAGAEVQ KPLATVVIGG LFTATFLTLI
VLPLLYIMFQ KKSSAPLKPI TAIITLLILV GSAGTSQAQS KRLPLDEVLQ MAKQNLQYGI
NQQAQAQNKA QTRAAGMLPK TGIFAENEDY RPTDSRGILK IGLSQSVAWP GLYKAQKNVF
KAQATYLQMN QSLIDADVKR DVRAAYYELW YLQDKQLLFS KLDSIYKSMS NAARLKVKTG
DSPGLDSISA IARMREMEAF IEQTKNDIQV QQQSLAQLLN TQEAILPLQQ PLEKMLFNLS
SADSLHPALA MQQQTVNVAQ AGIVVAKNEN LPEFSGRFFS QRLYGMKDPF SGFSVTTSIP
LASMGASKHK VKAAELEMAV EQKKFDYGMQ QFNTAKLQAV QNVMKNEQLL RFYESTGLEQ
AAAIIKASSL AYRSGEISFA ELSQFLSQAI TMQRNHLDQL NAYNQAIIQY NYFINQ
//
