ID A0A327VJQ3_9ACTN Unreviewed; 778 AA.
AC A0A327VJQ3;
DT 10-OCT-2018, integrated into UniProtKB/TrEMBL.
DT 10-OCT-2018, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=DNA helicase IV {ECO:0000313|EMBL:RAJ72543.1};
GN ORFNames=K377_07511 {ECO:0000313|EMBL:RAJ72543.1};
OS Streptomyces sp. PsTaAH-137.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1305830 {ECO:0000313|EMBL:RAJ72543.1, ECO:0000313|Proteomes:UP000249376};
RN [1] {ECO:0000313|EMBL:RAJ72543.1, ECO:0000313|Proteomes:UP000249376}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PsTaAH-137 {ECO:0000313|EMBL:RAJ72543.1,
RC ECO:0000313|Proteomes:UP000249376};
RA Currie C.;
RT "Biomass-degrading enzyme discovery via genome sequencing of insect-
RT associated Streptomyces.";
RL Submitted (JUN-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RAJ72543.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; QLLY01000026; RAJ72543.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A327VJQ3; -.
DR Proteomes; UP000249376; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003678; F:DNA helicase activity; IEA:InterPro.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-UniRule.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 3.
DR InterPro; IPR000212; DNA_helicase_UvrD/REP.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR014016; UvrD-like_ATP-bd.
DR InterPro; IPR027785; UvrD-like_helicase_C.
DR PANTHER; PTHR11070:SF45; ATP-DEPENDENT DNA HELICASE UVRD2; 1.
DR PANTHER; PTHR11070; UVRD / RECB / PCRA DNA HELICASE FAMILY MEMBER; 1.
DR Pfam; PF00580; UvrD-helicase; 1.
DR Pfam; PF13538; UvrD_C_2; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51198; UVRD_HELICASE_ATP_BIND; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00560};
KW Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000256|PROSITE-
KW ProRule:PRU00560};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|PROSITE-
KW ProRule:PRU00560};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00560}.
FT DOMAIN 214..629
FT /note="UvrD-like helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51198"
FT REGION 336..365
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 592..611
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 235..242
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00560"
SQ SEQUENCE 778 AA; 85140 MW; E6CDAFB5156187FD CRC64;
MDSVRDREIG VEQHHLDAVY RRLEEKIHEA EFLMDDAAKR GQVGTPGALA ERDAQVFRAG
IHLNRLNNEF EDFLFGRIDL LLGKDGKKGP DGAYTAVEPA EGAVREDNTA DIAETLHIGR
IGVLDADYSP LVIDWRAPAA APFYRSTPVD PGRVVRRRVI RSKGRKVLGV EDDLMRPELT
AYLDGAELPA IGDGALMAAL GQARSHSMRD IVASIQAEQD LVIRAPAASV TYVEGGPGTG
KTAVALHRAA YLLYQDRRRY AGGILIVSPT PLLVAYTEGV LPSLGEEGQV AIRAVGSLYD
GPGGAEATEY DSPAVARVKG SSRMLTVLRR AARGALESGR PAPARQEQLA FGEEEGETPA
PAAGTPTRLR VVAFGRRLEL EAGQLNRIRH AALGGTAPVN HLRPRARKLL LDALWEQSGS
AGRHTDPELA AELRSSFDAD ITGEDDFTRF LDAWWPELTP RAVLSAMADE RRLGRWARRV
LNPGEVRKLA RSLRREAFSV HDIALLDELN SVLGAPARPR RKREYDPLDQ LTGLEELMPV
REETQYERAE RLAQERTEYA HVIVDEAQDL TPMQWRMVGR RGRHATWTIV GDPAQSSWSD
PDEAAAARDE ALGSRPRRRF ELTVNYRNPS EIADLAAKVL ALAMPGSTSP SAVRSTGVQP
RFVVVRDRTA DTVREEAARL LERVDGTVGV VVAMNRRKEA ARWLAGLGDR VVALGSLEAK
GLEYDATIVV SPAEIADESP AGLRVLYVAL TRATQQLTVV SAERDEPDPE GVPDLLRD
//
