ID A0A327Z1S3_9ACTN Unreviewed; 506 AA.
AC A0A327Z1S3;
DT 10-OCT-2018, integrated into UniProtKB/TrEMBL.
DT 10-OCT-2018, sequence version 1.
DT 24-JAN-2024, entry version 16.
DE RecName: Full=Protein-L-isoaspartate O-methyltransferase {ECO:0000256|ARBA:ARBA00013346};
DE EC=2.1.1.77 {ECO:0000256|ARBA:ARBA00011890};
DE AltName: Full=L-isoaspartyl protein carboxyl methyltransferase {ECO:0000256|ARBA:ARBA00031350};
DE AltName: Full=Protein L-isoaspartyl methyltransferase {ECO:0000256|ARBA:ARBA00030757};
DE AltName: Full=Protein-beta-aspartate methyltransferase {ECO:0000256|ARBA:ARBA00031323};
GN ORFNames=B0I29_120102 {ECO:0000313|EMBL:RAK28334.1};
OS Actinoplanes lutulentus.
OC Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
OC Micromonosporaceae; Actinoplanes.
OX NCBI_TaxID=1287878 {ECO:0000313|EMBL:RAK28334.1, ECO:0000313|Proteomes:UP000249341};
RN [1] {ECO:0000313|EMBL:RAK28334.1, ECO:0000313|Proteomes:UP000249341}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CGMCC 4.7090 {ECO:0000313|EMBL:RAK28334.1,
RC ECO:0000313|Proteomes:UP000249341};
RA Whitman W.;
RT "Genomic Encyclopedia of Type Strains, Phase III (KMG-III): the genomes of
RT soil and plant-associated and newly described type strains.";
RL Submitted (JUN-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the methyltransferase superfamily. L-
CC isoaspartyl/D-aspartyl protein methyltransferase family.
CC {ECO:0000256|ARBA:ARBA00005369}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RAK28334.1}.
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DR EMBL; QLMJ01000020; RAK28334.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A327Z1S3; -.
DR OrthoDB; 4035289at2; -.
DR Proteomes; UP000249341; Unassembled WGS sequence.
DR GO; GO:0004719; F:protein-L-isoaspartate (D-aspartate) O-methyltransferase activity; IEA:InterPro.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR GO; GO:0036211; P:protein modification process; IEA:InterPro.
DR CDD; cd02440; AdoMet_MTases; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR027573; Methyltran_FxLD.
DR InterPro; IPR000682; PCMT.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR NCBIfam; TIGR04364; methyltran_FxLD; 1.
DR PANTHER; PTHR11579; PROTEIN-L-ISOASPARTATE O-METHYLTRANSFERASE; 1.
DR PANTHER; PTHR11579:SF0; PROTEIN-L-ISOASPARTATE(D-ASPARTATE) O-METHYLTRANSFERASE; 1.
DR Pfam; PF01135; PCMT; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
PE 3: Inferred from homology;
KW Methyltransferase {ECO:0000313|EMBL:RAK28334.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000249341};
KW Transferase {ECO:0000313|EMBL:RAK28334.1}.
FT REGION 92..113
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 506 AA; 54911 MW; E429ED9E5E9C88C2 CRC64;
MSHLAAPPTE MVEHIPVRPS WDCRACGEPW PCNAARSALS SEYRAFPSLL KMYLSTQMYE
AIGDLFGVNS ISPIDFYQRF LSWIRSPPTD DSAVHAEVPT NGATVSTPPS NDPDKLRAAM
VRTLIEEGTI LSGDVAAAFA AVPRHLFVPG EALWRAYDPQ LALLPKTAAN GTDTSVVSAA
EVQAAMLEQA QVERGMNVLE VGSGGYNAAL LAELVGPSGQ VTSVDIDSGI TARAGACLHK
TGYDQVRVIT ADATKLLPGQ SPFDRIIVTT AACDIAPAWI DELTPFGRIV VPLRFAGITR
VIAFDRNRGS RALFAHSYRL GSFVTMQGCA EERLIPLTRD VALRVDSQHT PEFHLPALRH
AIHEPPIEQW AGTAHDLPDE LQLFLLTNAQ PQMPILQASQ ELVDQGVFPT SARYGVPVLI
DGGSFAYRTS RPNPDIITGY ETGVVAHGPA AAKVADTLLA LIREWANNHF KRDAARIEYH
PKTMDTSDLL GWRVITQNGV LTVSWP
//
