ID A0A327Z2Z0_9ACTN Unreviewed; 1273 AA.
AC A0A327Z2Z0;
DT 10-OCT-2018, integrated into UniProtKB/TrEMBL.
DT 10-OCT-2018, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE SubName: Full=S-DNA-T family DNA segregation ATPase FtsK/SpoIIIE {ECO:0000313|EMBL:RAK27280.1};
GN ORFNames=B0I29_124171 {ECO:0000313|EMBL:RAK27280.1};
OS Actinoplanes lutulentus.
OC Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
OC Micromonosporaceae; Actinoplanes.
OX NCBI_TaxID=1287878 {ECO:0000313|EMBL:RAK27280.1, ECO:0000313|Proteomes:UP000249341};
RN [1] {ECO:0000313|EMBL:RAK27280.1, ECO:0000313|Proteomes:UP000249341}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CGMCC 4.7090 {ECO:0000313|EMBL:RAK27280.1,
RC ECO:0000313|Proteomes:UP000249341};
RA Whitman W.;
RT "Genomic Encyclopedia of Type Strains, Phase III (KMG-III): the genomes of
RT soil and plant-associated and newly described type strains.";
RL Submitted (JUN-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RAK27280.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; QLMJ01000024; RAK27280.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A327Z2Z0; -.
DR OrthoDB; 9807790at2; -.
DR Proteomes; UP000249341; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 3.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR023836; EccCa-like_Actinobacteria.
DR InterPro; IPR023837; EccCb-like_Actinobacteria.
DR InterPro; IPR002543; FtsK_dom.
DR InterPro; IPR027417; P-loop_NTPase.
DR NCBIfam; TIGR03924; T7SS_EccC_a; 1.
DR NCBIfam; TIGR03925; T7SS_EccC_b; 1.
DR PANTHER; PTHR22683; SPORULATION PROTEIN RELATED; 1.
DR PANTHER; PTHR22683:SF1; TYPE VII SECRETION SYSTEM PROTEIN ESSC; 1.
DR Pfam; PF01580; FtsK_SpoIIIE; 3.
DR SMART; SM00382; AAA; 3.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 3.
DR PROSITE; PS50901; FTSK; 3.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00289}; Membrane {ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00289}; Reference proteome {ECO:0000313|Proteomes:UP000249341};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 66..88
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 434..634
FT /note="FtsK"
FT /evidence="ECO:0000259|PROSITE:PS50901"
FT DOMAIN 779..949
FT /note="FtsK"
FT /evidence="ECO:0000259|PROSITE:PS50901"
FT DOMAIN 1043..1227
FT /note="FtsK"
FT /evidence="ECO:0000259|PROSITE:PS50901"
FT REGION 1..35
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 21..35
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 457..464
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00289"
FT BINDING 797..804
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00289"
FT BINDING 1060..1067
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00289"
SQ SEQUENCE 1273 AA; 137441 MW; A1BAB05DA0497058 CRC64;
MGTVTIRRPP RRAAPVIPTG ELTVDPPPPM PPQPAGRWQQ WLLALPMLGG TIAMAMMMGQ
GQSGPFSYVV GALFGISSLA MLTMSFSASG SPRKAEMIAA RRDYLRHLAG LRRRARETAR
AQRTGLFHRH PDPERLWSTV DSQRVWERRP EDSDFGVVRI GLGPQTLATP LVPPETRPPD
ELEPMTAGAL RRFLEAYSVV PDLPVAMSVR GFARILIRSE GDREAARALV RAVLTQLAVF
HPPDDLIIAI CAGPGAREAW EWVKWLPHNG HPERSDALGP IRLIGDPEVL DGLRPGPHLV
IVQDGSTHPL NPSLDGATVL DLDTTPPRLE DESTLVVAIS PNRTLRTSTL DHFAEVGRAD
QLDAAQAEAI ARRLTPLELD TDADPTGQTG QTADPGLAEL LGITDPETHP ATRGWISRPN
RGRLRVPIGV DPTGRPVELD LKESAQDGMG PHGLLVGATG SGKSELLRTL VLALAATHSP
ETLNFVLIDF KGGATFASMD RLPHTAALIT NLADALPLVD RMADALDGEL LRRQELLRRS
GNFAGLREYD RARAAGAVLP PLPSLLVICD EFSELLQRKP EFLDLFLQIG RLGRSLGVHL
LLSSQRIEDG RLRGLDTHLS YRIGLRTFSA LESRAVLGVA DAYELPRSPG HGFLKSGTEA
PARFRSAYAS GPSRRHRAPD ASTPRILPWT SEHIPLTEAP AEDSADRALA DVLVGRLAGK
GPPAHRVWLP PLDASATLDD LLGSVVPDPH RGLTVANPAL HGALQVPIAL VDKPREQVRD
TLWLQLAGSA GHVAVAGGTR SGKSSVLRAL ACGLALTHTP DEVRVYCLDF GGGTLAGLRD
LPHVGGVFGR LEPEGVRRTA GEMTSLLAER ERQAAPFWSH VFLVVDGWAT LRSDFEELEP
VLTDLATRGL AYGIHLVAAT SRWTDFRPPI RDLFGSRVEL RLGDPADSAV HRRAALAVPE
GRPGRGVTEH PADRDRGLHL LTVRPEVSTL GDTAALVKAV AGAWRGPVAP PVRLLPAVVA
YQRPESDPAG SLRVPIGIAE SDLLPVAIDF AADPHLLVLG DAECGKSSLL RALATSVTTL
FTPEQARIIL VDYRRSLMDL PVTEHRIGYG VQAQQTAELM RSVAGYMERR LPGPDVTAAQ
LRNRSWWTGP ELFVLVDDYD LVAAGPVNPL TPLLEHLPQA RDVGLHLVLT RRAGGAGRAL
YEPVIQRLRE LSAPGLVMSG SPEEGVLLGT VPARPMPPGR GHLVTRREGT RLIQLAHLPP
FRDSAKSTDS ECD
//
