ID A0A327Z6E3_9ACTN Unreviewed; 472 AA.
AC A0A327Z6E3;
DT 10-OCT-2018, integrated into UniProtKB/TrEMBL.
DT 10-OCT-2018, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=PhoH-like ATPase {ECO:0000313|EMBL:RAK32748.1};
GN ORFNames=B0I29_11343 {ECO:0000313|EMBL:RAK32748.1};
OS Actinoplanes lutulentus.
OC Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
OC Micromonosporaceae; Actinoplanes.
OX NCBI_TaxID=1287878 {ECO:0000313|EMBL:RAK32748.1, ECO:0000313|Proteomes:UP000249341};
RN [1] {ECO:0000313|EMBL:RAK32748.1, ECO:0000313|Proteomes:UP000249341}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CGMCC 4.7090 {ECO:0000313|EMBL:RAK32748.1,
RC ECO:0000313|Proteomes:UP000249341};
RA Whitman W.;
RT "Genomic Encyclopedia of Type Strains, Phase III (KMG-III): the genomes of
RT soil and plant-associated and newly described type strains.";
RL Submitted (JUN-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the PINc/VapC protein family.
CC {ECO:0000256|ARBA:ARBA00038093}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RAK32748.1}.
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DR EMBL; QLMJ01000013; RAK32748.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A327Z6E3; -.
DR OrthoDB; 9805148at2; -.
DR Proteomes; UP000249341; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0004518; F:nuclease activity; IEA:UniProtKB-KW.
DR CDD; cd09883; PIN_VapC_PhoHL-ATPase; 1.
DR Gene3D; 3.40.50.1010; 5'-nuclease; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR003714; PhoH.
DR InterPro; IPR029060; PIN-like_dom_sf.
DR InterPro; IPR002716; PIN_dom.
DR PANTHER; PTHR30473:SF2; PIN DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR30473; PROTEIN PHOH; 1.
DR Pfam; PF02562; PhoH; 1.
DR Pfam; PF13638; PIN_4; 1.
DR SMART; SM00670; PINc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF88723; PIN domain-like; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nuclease {ECO:0000256|ARBA:ARBA00022722};
KW Reference proteome {ECO:0000313|Proteomes:UP000249341};
KW Toxin-antitoxin system {ECO:0000256|ARBA:ARBA00022649}.
FT DOMAIN 46..173
FT /note="PIN"
FT /evidence="ECO:0000259|SMART:SM00670"
FT REGION 1..38
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..21
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 22..38
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 472 AA; 51457 MW; E92F516638103C8D CRC64;
MTSRRTDAGV ASNSDPADKV TKTRVTTSRR KVRDRHTDAE PAPAGRVFVL DTSVLLSDPA
AFRRFTDHEV IIPLVVISEL EGKRHHAELG WFARQALRML DELRIKFGRL DQPVLCNDEG
GTVRVELNHA DQSALPQGFR NDSNDTRILS VALGLAAEGR DVTLVSKDMP LRVKAASVGL
TADEYRHGQA SDPTWTGMAD LKLTEDQVVS LYAGDELELE EAENLPCHTG LVIHSSKGSA
LARVNPDKSV KLVRGDRDAF GLRGRSAEQR VALDILLDES VGIVSLGGRA GTGKSALALC
AGLEATMERN RHKKVIVFRP LYAVGGQELG YLPGSESEKM SPWAQAVFDT LGSVAHANVV
EEVMARGMLE VLPLTHIRGR SLHDAFVIVD EAQSLERNVL LTVLSRIGQN SRVVLTHDVA
QRDNLRVGRH DGVTAVIEAL KGHPIFAHVT LTRSERSPIA EVVTDLLEEI PL
//
