ID A0A328B1D6_9CAUL Unreviewed; 350 AA.
AC A0A328B1D6;
DT 10-OCT-2018, integrated into UniProtKB/TrEMBL.
DT 10-OCT-2018, sequence version 1.
DT 27-MAR-2024, entry version 13.
DE RecName: Full=3-hydroxyisobutyryl-CoA hydrolase {ECO:0000256|ARBA:ARBA00011915};
DE EC=3.1.2.4 {ECO:0000256|ARBA:ARBA00011915};
GN ORFNames=DJ021_16305 {ECO:0000313|EMBL:RAK61252.1};
OS Phenylobacterium hankyongense.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Caulobacterales;
OC Caulobacteraceae; Phenylobacterium.
OX NCBI_TaxID=1813876 {ECO:0000313|EMBL:RAK61252.1, ECO:0000313|Proteomes:UP000249842};
RN [1] {ECO:0000313|Proteomes:UP000249842}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HKS-05 {ECO:0000313|Proteomes:UP000249842};
RA Li X.;
RL Submitted (MAY-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=3-hydroxy-2-methylpropanoyl-CoA + H2O = 3-hydroxy-2-
CC methylpropanoate + CoA + H(+); Xref=Rhea:RHEA:20888,
CC ChEBI:CHEBI:11805, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378,
CC ChEBI:CHEBI:57287, ChEBI:CHEBI:57340; EC=3.1.2.4;
CC Evidence={ECO:0000256|ARBA:ARBA00001709};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RAK61252.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; QFYP01000001; RAK61252.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A328B1D6; -.
DR OrthoDB; 9790967at2; -.
DR Proteomes; UP000249842; Unassembled WGS sequence.
DR GO; GO:0003860; F:3-hydroxyisobutyryl-CoA hydrolase activity; IEA:InterPro.
DR GO; GO:0016853; F:isomerase activity; IEA:UniProtKB-KW.
DR CDD; cd06558; crotonase-like; 1.
DR InterPro; IPR029045; ClpP/crotonase-like_dom_sf.
DR InterPro; IPR045004; ECH_dom.
DR InterPro; IPR032259; HIBYL-CoA-H.
DR PANTHER; PTHR43176:SF3; 3-HYDROXYISOBUTYRYL-COA HYDROLASE, MITOCHONDRIAL; 1.
DR PANTHER; PTHR43176; 3-HYDROXYISOBUTYRYL-COA HYDROLASE-RELATED; 1.
DR Pfam; PF16113; ECH_2; 1.
DR SUPFAM; SSF52096; ClpP/crotonase; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Isomerase {ECO:0000313|EMBL:RAK61252.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000249842}.
FT DOMAIN 16..337
FT /note="Enoyl-CoA hydratase/isomerase"
FT /evidence="ECO:0000259|Pfam:PF16113"
SQ SEQUENCE 350 AA; 38479 MW; 66B3867CE75F7ABD CRC64;
MSDAEPEVLA RVEGRVGRLT LNRPQALHAL TTNMCRLMIE ALVAWRDDPA VQLVLLDHSG
ERGFCAGGDI RMLAESGAGD GRAAREFFFT EYRLNHLLFH YPKTTVAIMD GVTMGGGVGL
SRPCRFRVAT ERTTFAMPET GIGLFPDVGG GWYLPRMPDH IGLWLALTGA RIKAADCELV
GVATDCVESA DVEELKGWIV KDPPAIETLL TEFETDAGRP TLAAHQDEIA RLFSPPSVEA
IVSALKATDS DWAREQLAIL ATKSPQTMKV AFRQLRLGQA QTFAENMEME YRIAARVVRR
HDFLEGVRAV IVEKDNAPRW DPPTLEGVTE QMLDAIFAPL PSGEAWTPLP
//
