ID   A0A328B5T6_9CAUL        Unreviewed;      1192 AA.
AC   A0A328B5T6;
DT   10-OCT-2018, integrated into UniProtKB/TrEMBL.
DT   10-OCT-2018, sequence version 1.
DT   27-MAR-2024, entry version 15.
DE   SubName: Full=Aminopeptidase {ECO:0000313|EMBL:RAK62503.1};
GN   ORFNames=DJ019_18975 {ECO:0000313|EMBL:RAK62503.1};
OS   Phenylobacterium kunshanense.
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; Caulobacterales;
OC   Caulobacteraceae; Phenylobacterium.
OX   NCBI_TaxID=1445034 {ECO:0000313|EMBL:RAK62503.1, ECO:0000313|Proteomes:UP000249524};
RN   [1] {ECO:0000313|EMBL:RAK62503.1, ECO:0000313|Proteomes:UP000249524}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=BUT-10 {ECO:0000313|EMBL:RAK62503.1,
RC   ECO:0000313|Proteomes:UP000249524};
RA   Lanie J.A., Ng W.-L., Kazmierczak K.M., Andrzejewski T.M., Davidsen T.M.,
RA   Wayne K.J., Tettelin H., Glass J.I., Rusch D., Podicherti R., Tsui H.-C.T.,
RA   Winkler M.E.;
RL   Submitted (MAY-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:RAK62503.1}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; QFYS01000011; RAK62503.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A328B5T6; -.
DR   OrthoDB; 100605at2; -.
DR   Proteomes; UP000249524; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0004177; F:aminopeptidase activity; IEA:UniProtKB-KW.
DR   GO; GO:0008237; F:metallopeptidase activity; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   Gene3D; 1.10.390.10; Neutral Protease Domain 2; 1.
DR   InterPro; IPR014782; Peptidase_M1_dom.
DR   InterPro; IPR027268; Peptidase_M4/M1_CTD_sf.
DR   Pfam; PF01433; Peptidase_M1; 1.
DR   SUPFAM; SSF55486; Metalloproteases ('zincins'), catalytic domain; 1.
PE   4: Predicted;
KW   Aminopeptidase {ECO:0000313|EMBL:RAK62503.1};
KW   Hydrolase {ECO:0000313|EMBL:RAK62503.1};
KW   Membrane {ECO:0000256|SAM:Phobius}; Protease {ECO:0000313|EMBL:RAK62503.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000249524};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        18..36
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        56..79
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        100..125
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        145..168
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        175..195
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        243..262
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        316..337
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        349..372
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        403..426
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        438..462
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        474..495
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        515..537
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        557..580
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          865..1058
FT                   /note="Peptidase M1 membrane alanine aminopeptidase"
FT                   /evidence="ECO:0000259|Pfam:PF01433"
SQ   SEQUENCE   1192 AA;  132930 MW;  6AD976195BA7B3E8 CRC64;
     MFGRIAAFEL RYQLRQPVFW IAGLMFFALV FGAVGIDRIQ IGSGGNVHKN SPKAIGEIVM
     VMTVFFMFVS TAFVANVIVR DEETGFGPII RSTAVRKFDY LFGRFSGAFA ACALCFLFVP
     AAIWIGSLMP WVDPETMGPN RLGDFAFAYV WLALPGLFLT SAIFFALATV TRSMMATYLG
     VAGFLVAYIV MSVALQDPSR LPLAALVEPF GLAAWELSTR YFTAAESNTR MPDLAGPLLT
     NRLIWIPVAV GFLALAGLTF RFEARPTRAR RTLLAGRDVP PPGLKPLAAP GKGLAVAWAQ
     LASRTRFDMA QVFKSPAFGV LLALGLFNSL GSLIFGAEAD GAALYPVTRW VITTLLGSFA
     FLVPIVAVYY AGELVWRERE RRTHEIIDAT AAPDWTFVVP KTLAIALVLM AMLAVSALTG
     VAVQLFSGFH QTQPEKYLLW YILPHALDFT LIAVLAVFFQ AVSPHKFVGW GLMVLYLIAI
     LVLPTIGFEH NLYLYGGRPS VPLSDMNGQG DFAGYAAWFR AYWSAFAVLL MVLAWGLWRR
     GTETRFSPRL KRLPRRLVGP GGVIAGVALL AFAGLGAHIF RNTNIDNEYR TSVEGERWLA
     DYEKAFLKYE SLPQPSVTDV ELDLDLHPRE PKLVTEGVYH LLNDTGAPVR ELHVRLDRDT
     KALQMSVNGA SRVRTFDRFN YRIFTFDRPL MPGERTALSF QTVMGQWGFK NSGNMTRIVD
     NGTFVDNFEF APIVGMDRAR LLQERAKRRK YGLTPQLRPA KLENRSAQAR NYLANADWVN
     ADIRVTTDAD QTPVAPGYRI SDETNKGRRT VRYRTEAPVL HFFSVQSARY AVRRESYKGV
     ELEVYHDPQH PWNVERMIAA LKTGLDYYQA NFGPYQFRQA RILEFPDYAA FAQAFANTMP
     YSEGIGFVAD NTKPDKIDYV TYVTAHELAH QWWAHQVIGA DMQGATALSE TLAQYSALIV
     MEKTYGADRI RKFLKYELDR YLRSRGGEVV EELPLIRVEN QPYIHYRKGS LVMYLLRDRL
     GEAKVNAALR RLLQQHAFKG APYPRSQDLV DALRAEAGND PAAQQLISDL FERITVYDLK
     TRTAVARKRG DGRYDVTLTV EAKKAYADGQ GSETAVAIPA GEAFDLGVFT AEPGKPGFTS
     RDVLAFRPVS LKSGVQTLTV TVDRLPKFAG VDPYNKQIDR ASDDNAIAVE AR
//