ID   A0A328EGY8_9BACT        Unreviewed;      1135 AA.
AC   A0A328EGY8;
DT   10-OCT-2018, integrated into UniProtKB/TrEMBL.
DT   10-OCT-2018, sequence version 1.
DT   22-FEB-2023, entry version 12.
DE   RecName: Full=PKD domain-containing protein {ECO:0000259|PROSITE:PS50093};
GN   ORFNames=BLD25_04080 {ECO:0000313|EMBL:RAL55819.1};
OS   Candidatus Gracilibacteria bacterium GN02-872.
OC   Bacteria; Candidatus Gracilibacteria.
OX   NCBI_TaxID=1912928 {ECO:0000313|EMBL:RAL55819.1, ECO:0000313|Proteomes:UP000249870};
RN   [1] {ECO:0000313|EMBL:RAL55819.1, ECO:0000313|Proteomes:UP000249870}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=GN02-872 {ECO:0000313|EMBL:RAL55819.1};
RA   Podar M.;
RT   "Genome sequence of human oral bacteria from candidate phyla GN02
RT   ('Gracilibacteria) and SR1.";
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:RAL55819.1}.
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DR   EMBL; MOLU01000006; RAL55819.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A328EGY8; -.
DR   Proteomes; UP000249870; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   CDD; cd00146; PKD; 2.
DR   Gene3D; 2.60.40.10; Immunoglobulins; 2.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR022409; PKD/Chitinase_dom.
DR   InterPro; IPR000601; PKD_dom.
DR   InterPro; IPR035986; PKD_dom_sf.
DR   Pfam; PF18911; PKD_4; 2.
DR   SMART; SM00089; PKD; 2.
DR   SUPFAM; SSF49299; PKD domain; 2.
DR   PROSITE; PS50093; PKD; 2.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000249870};
KW   Signal {ECO:0000256|SAM:SignalP}; Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   SIGNAL          1..20
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           21..1135
FT                   /note="PKD domain-containing protein"
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5016249164"
FT   TRANSMEM        1111..1129
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          674..736
FT                   /note="PKD"
FT                   /evidence="ECO:0000259|PROSITE:PS50093"
FT   DOMAIN          1016..1078
FT                   /note="PKD"
FT                   /evidence="ECO:0000259|PROSITE:PS50093"
FT   REGION          31..125
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          232..291
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        45..59
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        60..125
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1135 AA;  129743 MW;  36B4E6A7A72BEF5D CRC64;
     MTFKKIFTTF FIFVFSFSSV FSVNENTSLA SEESNKIESQ NSQDVIVPKR DDDKDSQKFK
     LNNSSTGTTS ENLGIQDGSQ NTSNPSQSTN SGNINNSLTG SGNSSSGTGS QNSNSGTTNS
     GSIGSSFEQN FQIKNTFQNP TYLLEKDQEK EEYFCEKDDC KVNFDFRQSF SENFKQKDFT
     CEFYVSGSLV EENCNPKTIE IVEKETILKI KILKKSDKNI FKEKEFKIFK NNQNSGTGSS
     NTGSMNSGMT NSGTISTGST NSGTTNSGSQ NNSLTGVTNS GNTNSGSINS PSTNTGITIS
     DFAKNFQIKN IFQNPTYLLE KDQEKDEYFC DSFNDCKVNF DFRSSFSEDF KQKDFVCEFF
     SSGSLIEENC NPKTIEIKEL ENIFEIKVSK KTDKSIFKKR EIKIIKRQNI SSTGTTNSGI
     VNSGSTNSGN LNSDFEQNFQ IKNIFQKPTY LIEKEKDKSE YLCESSICKV NFDFRSSFSE
     DFKQKDFICE FYSSGSLIEE NCNPKTVDII EKETIFKVKI LKKSDKNIFK EREFKILKNN
     SGISAQTQDF VKPRIVVQSG LNDKKCLTKD CKVNFTFSTK NKNLRCEWTF GNGDFKLGTE
     KKCNPSAVSF PYGKHLVVLK VFDKKNGTLY GEDLLEFENT FEPKNLEAEI ILTGKSKKYQ
     LWSGFALCLD EKCNFNFSAY NSSKDIKEYL WDFGNGKTFE GKNPSIQTFG PGNHKISLKV
     FDEKNNSKEY FYNIEVRKNI LKEIFEKKQE KKLFPLKIRK NQNFLIISGN SKKNILVKKY
     STSALTGYFP DEIFEIIPDQ NGDFKKELPH KRAGNFIFEF YQIGENGEEI FSEKRKIEIT
     YKDYFISNFN KLEPKTQKVK KARTIKKNAV KNQKQQEKKF LEIYLQGKQT KNKIINGKKV
     KCIGTCSLNF GLKTNIKQKN ISWKLGNGET FEGKNPKSKK FLPGKYKIEV EFIDEKGEKL
     LDFFEVEVVK KVRKKRARKS KKIKTGPVNL IIEVQGRASK NKILSENKLT CYKTCNVNFD
     GRKSSGAYKS LNWDFGNGET FTGENPKSVK YLKPGKYKVL LKTEDFKGKT YEKIFEVEFI
     EKPINTYSKQ ISNKNVLEEE LKEKDLEKQD FFFIFTIIFL IGSGSFILLR KYNII
//