ID A0A328SJX5_9EURY Unreviewed; 554 AA.
AC A0A328SJX5;
DT 10-OCT-2018, integrated into UniProtKB/TrEMBL.
DT 10-OCT-2018, sequence version 1.
DT 24-JAN-2024, entry version 17.
DE SubName: Full=Fumarate reductase subunit A {ECO:0000313|EMBL:RAP53941.1};
GN ORFNames=BZ137_04945 {ECO:0000313|EMBL:RAP53941.1};
OS Methanosphaera sp. rholeuAM130.
OC Archaea; Euryarchaeota; Methanomada group; Methanobacteria;
OC Methanobacteriales; Methanobacteriaceae; Methanosphaera.
OX NCBI_TaxID=1945578 {ECO:0000313|EMBL:RAP53941.1, ECO:0000313|Proteomes:UP000248969};
RN [1] {ECO:0000313|EMBL:RAP53941.1, ECO:0000313|Proteomes:UP000248969}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=RholeuAM130 {ECO:0000313|EMBL:RAP53941.1};
RA Hoedt E.C., Parks D.H., Rosewarne C.P., Denman S.E., Mcsweeney C.S.,
RA O Cuiv P., Hugenholtz P., Tyson G.W., Morrison M.;
RT "Culture- and metagenomics-based expansion of the genus Methanosphaera
RT reveals their evolutionary depth and metabolic versatility.";
RL Submitted (JAN-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RAP53941.1}.
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DR EMBL; MUZY01000135; RAP53941.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A328SJX5; -.
DR Proteomes; UP000248969; Unassembled WGS sequence.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR Gene3D; 1.20.58.100; Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal domain; 1.
DR Gene3D; 3.90.700.10; Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain; 1.
DR InterPro; IPR003953; FAD-binding_2.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR037099; Fum_R/Succ_DH_flav-like_C_sf.
DR InterPro; IPR015939; Fum_Rdtase/Succ_DH_flav-like_C.
DR InterPro; IPR030664; SdhA/FrdA/AprA.
DR InterPro; IPR027477; Succ_DH/fumarate_Rdtase_cat_sf.
DR PANTHER; PTHR11632; SUCCINATE DEHYDROGENASE 2 FLAVOPROTEIN SUBUNIT; 1.
DR PANTHER; PTHR11632:SF51; SUCCINATE DEHYDROGENASE [UBIQUINONE] FLAVOPROTEIN SUBUNIT, MITOCHONDRIAL; 1.
DR Pfam; PF00890; FAD_binding_2; 1.
DR Pfam; PF02910; Succ_DH_flav_C; 1.
DR PIRSF; PIRSF000171; SDHA_APRA_LASPO; 1.
DR PRINTS; PR00368; FADPNR.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
DR SUPFAM; SSF46977; Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain; 1.
DR SUPFAM; SSF56425; Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain; 1.
DR PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE 4: Predicted;
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022630};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002}.
FT DOMAIN 9..389
FT /note="FAD-dependent oxidoreductase 2 FAD binding"
FT /evidence="ECO:0000259|Pfam:PF00890"
FT DOMAIN 443..544
FT /note="Fumarate reductase/succinate dehydrogenase
FT flavoprotein-like C-terminal"
FT /evidence="ECO:0000259|Pfam:PF02910"
FT ACT_SITE 285
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR000171-1"
SQ SEQUENCE 554 AA; 61356 MW; A6E2510FF518D167 CRC64;
MDIKKYECDV LIIGSGGAGC KCGIVASKHD ANVIIVSKGL SFRSGCTMLA EGGYNAVFGY
VDEEDSLQLH IQDTLKGGAF LNDLLLVHKL VTDSPKRLIE LESYGSLFDR QEDGRLNQRP
FGGQSYRRTC FKGDQTGHEM MLGLREEVIR ENITTHDEIM ITKLLFDDDH SKIVGAMGLN
LKDSSIVVYN SKTTVIAAGG CGWLYPVTSN ASQKTGDGVM IAYNAGADVM DMEMVQFHPT
GMLSPKSRRG VLITEAVRGE GGHLINSKGE RFMINYDERQ ELATRDIVAR AIYSEIQAGR
ASPLGGVYLS VEHLPEEQVM TKLHTMVEQF KDVGVDIVNE PMEVAPTAHH FMGGIKITPD
CQTNIENLYA AGEVTSGVHG ANRLGGNALA DTQVFGKAAG LKCSENIKEL ELTPASQSDI
DDEIERIEGI WSDGKYNPDD IKEQIQHVMW KYVAIVRDEE GLLEAQRQLN DLEEKTKDMD
VPSFNEYNNK LMLALEVISM IQLAKLIVKS ALLRKESRGA HYRSDYPNLN DEEYLKSFVL
NKNGEVKTVE RGLF
//
