ID A0A328SQ66_9EURY Unreviewed; 404 AA.
AC A0A328SQ66;
DT 10-OCT-2018, integrated into UniProtKB/TrEMBL.
DT 10-OCT-2018, sequence version 1.
DT 27-MAR-2024, entry version 16.
DE RecName: Full=Chloride channel protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=BZ137_04320 {ECO:0000313|EMBL:RAP54055.1};
OS Methanosphaera sp. rholeuAM130.
OC Archaea; Euryarchaeota; Methanomada group; Methanobacteria;
OC Methanobacteriales; Methanobacteriaceae; Methanosphaera.
OX NCBI_TaxID=1945578 {ECO:0000313|EMBL:RAP54055.1, ECO:0000313|Proteomes:UP000248969};
RN [1] {ECO:0000313|EMBL:RAP54055.1, ECO:0000313|Proteomes:UP000248969}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=RholeuAM130 {ECO:0000313|EMBL:RAP54055.1};
RA Hoedt E.C., Parks D.H., Rosewarne C.P., Denman S.E., Mcsweeney C.S.,
RA O Cuiv P., Hugenholtz P., Tyson G.W., Morrison M.;
RT "Culture- and metagenomics-based expansion of the genus Methanosphaera
RT reveals their evolutionary depth and metabolic versatility.";
RL Submitted (JAN-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RAP54055.1}.
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DR EMBL; MUZY01000116; RAP54055.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A328SQ66; -.
DR Proteomes; UP000248969; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005247; F:voltage-gated chloride channel activity; IEA:InterPro.
DR CDD; cd00400; Voltage_gated_ClC; 1.
DR Gene3D; 1.10.3080.10; Clc chloride channel; 1.
DR InterPro; IPR014743; Cl-channel_core.
DR InterPro; IPR001807; Cl-channel_volt-gated.
DR PANTHER; PTHR43427; CHLORIDE CHANNEL PROTEIN CLC-E; 1.
DR PANTHER; PTHR43427:SF6; CHLORIDE CHANNEL PROTEIN CLC-E; 1.
DR Pfam; PF00654; Voltage_CLC; 1.
DR SUPFAM; SSF81340; Clc chloride channel; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 7..29
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 49..67
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 96..124
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 144..163
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 183..202
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 222..241
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 262..282
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 294..316
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 328..355
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 367..395
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 404 AA; 44010 MW; 69A5AFF6D7B7C57F CRC64;
MENLKNNIIL LLYTVLVGII SGAIIWTFLK VMNLSIDFFW DYLPGIVDFK YYTITVSLIG
GLLIGLFKEK YGDATRELKE VTRKVKKDHR YPYNNIIPSI ISAILPLTFG ASVGPEAGLA
GIIASLCTWA SDKLKLFNKE LEDLTAIGVS ATLGVIFVSP LFAFVEPLEN EEDVKLPKTS
KNILYFAAIL SSFAIFVLLN QLTGSKMGIQ SLGNATLTNL NHIHILLLML VGILLAYFYF
ITNKYVKMIF NKLGDSFILK GIIGGLLLGI IGTILPLAMF SGEHQIDIVM ANGMEIGVVV
LIVTAVMKIF LTNICIESGL KGGHFFPLIF SGIAMGYAMS ILLNTNVIIA ASIVTTALLS
NILKKPIAVV LLLLILFPAN LIPLMLLTAA VSCLFKTPEG LAVE
//
