ID   A0A328WMR5_9FLAO        Unreviewed;       386 AA.
AC   A0A328WMR5;
DT   10-OCT-2018, integrated into UniProtKB/TrEMBL.
DT   10-OCT-2018, sequence version 1.
DT   27-MAR-2024, entry version 13.
DE   SubName: Full=3-hydroxybutyryl-CoA dehydrogenase {ECO:0000313|EMBL:RAR47561.1};
GN   ORFNames=B0I10_10863 {ECO:0000313|EMBL:RAR47561.1};
OS   Flavobacterium lacus.
OC   Bacteria; Bacteroidota; Flavobacteriia; Flavobacteriales;
OC   Flavobacteriaceae; Flavobacterium.
OX   NCBI_TaxID=1353778 {ECO:0000313|EMBL:RAR47561.1, ECO:0000313|Proteomes:UP000249518};
RN   [1] {ECO:0000313|EMBL:RAR47561.1, ECO:0000313|Proteomes:UP000249518}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CGMCC 1.12504 {ECO:0000313|EMBL:RAR47561.1,
RC   ECO:0000313|Proteomes:UP000249518};
RA   Whitman W.;
RT   "Genomic Encyclopedia of Type Strains, Phase III (KMG-III): the genomes of
RT   soil and plant-associated and newly described type strains.";
RL   Submitted (JUN-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:RAR47561.1}.
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DR   EMBL; QLSV01000008; RAR47561.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A328WMR5; -.
DR   Proteomes; UP000249518; Unassembled WGS sequence.
DR   GO; GO:0070403; F:NAD+ binding; IEA:InterPro.
DR   GO; GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR   GO; GO:0044248; P:cellular catabolic process; IEA:UniProt.
DR   GO; GO:0006631; P:fatty acid metabolic process; IEA:InterPro.
DR   GO; GO:1901575; P:organic substance catabolic process; IEA:UniProt.
DR   Gene3D; 1.10.1040.50; -; 1.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR006180; 3-OHacyl-CoA_DH_CS.
DR   InterPro; IPR006176; 3-OHacyl-CoA_DH_NAD-bd.
DR   InterPro; IPR006108; 3HC_DH_C.
DR   InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   PANTHER; PTHR48075; 3-HYDROXYACYL-COA DEHYDROGENASE FAMILY PROTEIN; 1.
DR   PANTHER; PTHR48075:SF5; 3-HYDROXYACYL-COA DEHYDROGENASE FAMILY PROTEIN; 1.
DR   Pfam; PF00725; 3HCDH; 2.
DR   Pfam; PF02737; 3HCDH_N; 1.
DR   SUPFAM; SSF48179; 6-phosphogluconate dehydrogenase C-terminal domain-like; 2.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR   PROSITE; PS00067; 3HCDH; 1.
DR   PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE   4: Predicted;
FT   DOMAIN          6..184
FT                   /note="3-hydroxyacyl-CoA dehydrogenase NAD binding"
FT                   /evidence="ECO:0000259|Pfam:PF02737"
FT   DOMAIN          187..284
FT                   /note="3-hydroxyacyl-CoA dehydrogenase C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF00725"
FT   DOMAIN          300..383
FT                   /note="3-hydroxyacyl-CoA dehydrogenase C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF00725"
SQ   SEQUENCE   386 AA;  43701 MW;  1935F6903E63A52B CRC64;
     METNLKVAVI GSGTMGSGIA QVAATAGCHV HLYDTNHAAL EKSENNLETT LSRLVEKEKI
     DETEKDRIIN NISYTTTFAE LSHSDLVIEA IVENLDIKRK LFSELENYVA PETILASNTS
     SLSIASIAAS CQKPERVIGI HFFNPAPLMQ LVEVIPAIQT SEEVLEKTVQ TITDWKKVVA
     IAKDTPGFIV NRVARPFYSE ALRIYEEGKA DFASIDWSMK TIGGFRMGPF ELMDFIGNDV
     NYTVTETVFT AFYFDPRYKP SFTQKRLSEA CYFGRKSGRG FYNYNSELPK PTEDNQLGQY
     IVDRILVMLI NEAAEAFFLN IASAKDIDNA MTKGVNYPKG LLTWADEKGI NWCVEKLDEL
     YNEYHEDRYR CSPILRKMNR ENKNFF
//