ID   A0A329KLD1_9BACL        Unreviewed;      1040 AA.
AC   A0A329KLD1;
DT   10-OCT-2018, integrated into UniProtKB/TrEMBL.
DT   10-OCT-2018, sequence version 1.
DT   27-MAR-2024, entry version 16.
DE   SubName: Full=Alpha-mannosidase {ECO:0000313|EMBL:RAU96377.1};
GN   ORFNames=DQG13_20705 {ECO:0000313|EMBL:RAU96377.1};
OS   Paenibacillus sp. YN15.
OC   Bacteria; Bacillota; Bacilli; Bacillales; Paenibacillaceae; Paenibacillus.
OX   NCBI_TaxID=1742774 {ECO:0000313|EMBL:RAU96377.1, ECO:0000313|Proteomes:UP000251619};
RN   [1] {ECO:0000313|EMBL:RAU96377.1, ECO:0000313|Proteomes:UP000251619}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=YN15 {ECO:0000313|EMBL:RAU96377.1,
RC   ECO:0000313|Proteomes:UP000251619};
RA   Niu L.;
RT   "Paenibacillus sp.YN15.";
RL   Submitted (JUN-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the glycosyl hydrolase 38 family.
CC       {ECO:0000256|ARBA:ARBA00009792}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:RAU96377.1}.
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DR   EMBL; QMFA01000029; RAU96377.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A329KLD1; -.
DR   OrthoDB; 9772207at2; -.
DR   Proteomes; UP000251619; Unassembled WGS sequence.
DR   GO; GO:0004559; F:alpha-mannosidase activity; IEA:InterPro.
DR   GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006013; P:mannose metabolic process; IEA:InterPro.
DR   CDD; cd10789; GH38N_AMII_ER_cytosolic; 1.
DR   Gene3D; 2.60.120.260; Galactose-binding domain-like; 1.
DR   Gene3D; 3.20.110.10; Glycoside hydrolase 38, N terminal domain; 1.
DR   Gene3D; 1.20.1270.50; Glycoside hydrolase family 38, central domain; 1.
DR   InterPro; IPR011013; Gal_mutarotase_sf_dom.
DR   InterPro; IPR008979; Galactose-bd-like_sf.
DR   InterPro; IPR041147; GH38_C.
DR   InterPro; IPR011330; Glyco_hydro/deAcase_b/a-brl.
DR   InterPro; IPR011682; Glyco_hydro_38_C.
DR   InterPro; IPR015341; Glyco_hydro_38_cen.
DR   InterPro; IPR037094; Glyco_hydro_38_cen_sf.
DR   InterPro; IPR000602; Glyco_hydro_38_N.
DR   InterPro; IPR027291; Glyco_hydro_38_N_sf.
DR   InterPro; IPR028995; Glyco_hydro_57/38_cen_sf.
DR   PANTHER; PTHR46017; ALPHA-MANNOSIDASE 2C1; 1.
DR   PANTHER; PTHR46017:SF1; ALPHA-MANNOSIDASE 2C1; 1.
DR   Pfam; PF09261; Alpha-mann_mid; 1.
DR   Pfam; PF17677; Glyco_hydro38C2; 1.
DR   Pfam; PF07748; Glyco_hydro_38C; 1.
DR   Pfam; PF01074; Glyco_hydro_38N; 1.
DR   SMART; SM00872; Alpha-mann_mid; 1.
DR   SUPFAM; SSF88688; Families 57/38 glycoside transferase middle domain; 1.
DR   SUPFAM; SSF74650; Galactose mutarotase-like; 1.
DR   SUPFAM; SSF49785; Galactose-binding domain-like; 1.
DR   SUPFAM; SSF88713; Glycoside hydrolase/deacetylase; 1.
PE   3: Inferred from homology;
KW   Glycosidase {ECO:0000256|ARBA:ARBA00023295};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00023295};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Reference proteome {ECO:0000313|Proteomes:UP000251619}.
FT   DOMAIN          520..598
FT                   /note="Glycoside hydrolase family 38 central"
FT                   /evidence="ECO:0000259|SMART:SM00872"
SQ   SEQUENCE   1040 AA;  117549 MW;  072993040E2EC624 CRC64;
     MTLSKEWKNR VELWKNELPK HYYTPLDTIV LEGYTTFDRL SMEEALKGGF QPFPPGTLWG
     AKWEYGWFRG SIVLPSAAQG KRIVLRLDVG GESTVFINGR AAGCVRRYEA WQAMNPVHVN
     ILTLERAAQA EAEYELVIEC YAGHGARVAH VGPVPPGRET IPEPPAQQAA MGVCTYGIWN
     EEIYQLWLDV EALYQVRGLL DPNSLRVAQI DKALMDFTLL VDVELPFEEM LATAAAARQR
     LKPLLACTNG TTAPEMFAFG HSHLDICYQW TLAETRRKCA RTLSTQMTLM DEYPDYRFLL
     SQPYLYEMTK QDYPELYERL KEKVRNGQIM PEGAMWVEAD TNIPSGESLI RQFLHGMEFF
     RSEFGIDSQL LWLPDVFGYT GALPQIMKGC GVKYFSTAKL LSSFVTGEPF PYNTFTWRGI
     DGTEVPVSLC ENYCAHMYPE AVTEVWSRRV QKDGVSSFLY PFGHGDGGGG ATRDHLEFLG
     RVRDLEGVPR VKISHPVDFF EDLEARGFPE AAYVGELYFQ AHRGTYTSQA RMKRWNRRSE
     TALRETELWG AAAQIVQNYA YPRETMDRIW KELLFLQFHD ILPGSSIHQV FVEAEESYRK
     LWGHNAEVRH EAQSSLLQDR PGWITVFNST GWDRRELVLL PPGTAQAVDS AGKELKLQEV
     EGRIYAEADV PSCGWTALQV GKKAQLASAG EPRPQVAAGE GWLENDLLRL ELNEYGELTV
     ILDKSTGRNL AAAPCNVFRM YKDVPGVCDA WEIEIMYEQQ PVALTDMASI EVVAQGELFG
     QLRVSRRLHA SELVQTITLR QGSRRVDFET TVEWREKHKL LKVSFPVDIH TDEAMHEIQY
     GYVKRPNHRS RTYDADRFEV CQHRWSALAE ANRGCALLND CKYGISVLGN SMNLTLLKAA
     LAPDMTADLG RQEFTYSFTF WNGPFVESNV IREAYGLNTP VISMEGWADE RSLFGIDCPA
     VVLDTVKPAE DGSGDLILRL YESMGTSASC TLNTSIPIRK VVETTMREAA VTELAFGPSG
     IPLSLRPFEV KTIRLSHRTE
//