ID A0A329QHI5_9ACTN Unreviewed; 983 AA.
AC A0A329QHI5;
DT 10-OCT-2018, integrated into UniProtKB/TrEMBL.
DT 10-OCT-2018, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE RecName: Full=galactosylceramidase {ECO:0000256|ARBA:ARBA00012657};
DE EC=3.2.1.46 {ECO:0000256|ARBA:ARBA00012657};
DE AltName: Full=Galactosylceramidase {ECO:0000256|ARBA:ARBA00033098};
GN ORFNames=DPM12_16515 {ECO:0000313|EMBL:RAW11441.1};
OS Phytoactinopolyspora halophila.
OC Bacteria; Actinomycetota; Actinomycetes; Jiangellales; Jiangellaceae;
OC Phytoactinopolyspora.
OX NCBI_TaxID=1981511 {ECO:0000313|EMBL:RAW11441.1, ECO:0000313|Proteomes:UP000250462};
RN [1] {ECO:0000313|EMBL:RAW11441.1, ECO:0000313|Proteomes:UP000250462}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=YIM 96934 {ECO:0000313|EMBL:RAW11441.1,
RC ECO:0000313|Proteomes:UP000250462};
RA Tang S.-K.;
RT "Phytoactinopolyspora halophila sp. nov., a novel halophilic actinomycete
RT isolated from a saline soil in China.";
RL Submitted (JUN-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 59 family.
CC {ECO:0000256|ARBA:ARBA00005637}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RAW11441.1}.
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DR EMBL; QMIG01000020; RAW11441.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A329QHI5; -.
DR OrthoDB; 9806701at2; -.
DR Proteomes; UP000250462; Unassembled WGS sequence.
DR GO; GO:0004336; F:galactosylceramidase activity; IEA:UniProtKB-EC.
DR GO; GO:0006683; P:galactosylceramide catabolic process; IEA:InterPro.
DR Gene3D; 3.20.20.70; Aldolase class I; 1.
DR Gene3D; 2.60.120.260; Galactose-binding domain-like; 2.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR InterPro; IPR013785; Aldolase_TIM.
DR InterPro; IPR000421; FA58C.
DR InterPro; IPR008979; Galactose-bd-like_sf.
DR InterPro; IPR049162; GH59_C.
DR InterPro; IPR049161; GH59_cat.
DR InterPro; IPR001286; Glyco_hydro_59.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR PANTHER; PTHR15172; GALACTOCEREBROSIDASE; 1.
DR PANTHER; PTHR15172:SF1; GALACTOCEREBROSIDASE; 1.
DR Pfam; PF00754; F5_F8_type_C; 2.
DR Pfam; PF02057; Glyco_hydro_59; 1.
DR Pfam; PF21708; Glyco_hydro_59_C; 1.
DR PRINTS; PR00850; GLHYDRLASE59.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR SUPFAM; SSF49785; Galactose-binding domain-like; 2.
DR PROSITE; PS50022; FA58C_3; 2.
PE 3: Inferred from homology;
KW Glycosidase {ECO:0000256|ARBA:ARBA00023295};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Lipid degradation {ECO:0000256|ARBA:ARBA00022963};
KW Lipid metabolism {ECO:0000256|ARBA:ARBA00022919};
KW Reference proteome {ECO:0000313|Proteomes:UP000250462};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP};
KW Sphingolipid metabolism {ECO:0000256|ARBA:ARBA00022919}.
FT SIGNAL 1..30
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 31..983
FT /note="galactosylceramidase"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5016320654"
FT DOMAIN 663..815
FT /note="F5/8 type C"
FT /evidence="ECO:0000259|PROSITE:PS50022"
FT DOMAIN 828..982
FT /note="F5/8 type C"
FT /evidence="ECO:0000259|PROSITE:PS50022"
FT REGION 818..841
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 983 AA; 106779 MW; 184375B57043EAD8 CRC64;
MQLQRRRAAG TVAIAALAGS WMVAIPPGQA AEDATVDGAQ HETVVVDGDS AGRTFDGLGA
VSAGASSRLL YDYPEPERSQ ILDYLFEPGY GAELEILKVE IGGDTNSTSG AEPSHMRTPD
EIDCGRGYEW WLMREAQERN PDIKLGGLQW GAPGWFDGGF WSQDNIDYLL NWLDCAEQHD
IDIDFMGGWN EAGYDQEWFV EWDAALDEHY PDVQLTAADD TPYWGWRVAD DMVENADFGD
AVDIANMHSP CGWRSTYAEC SSTQTARSLD KPLWIGEQSS MAHDAGAAPL ARGANRMYID
AAITGMMVWS PISAWYSNIT MADTGLMVAE WPWSGFYDVG DSIWSYAHTN QFADPGWRYL
DTGSERLESG ATQVSLVSPS GDDWSAVIET FDMDEPSSVT LQLENLPGKQ LQVWSSDLRT
DDDADRFRRA GVLTPEGGSV TLDVEPGHIY SVTTSDGQGK GDAQPGASVD ERLSVPFQET
FEDVDHGRTA RYFSDLAGAF EAAPCDGDRD GTCYRQMLAE EPISWTHVGE VPLSTMVGDP
RWWGDYAVHA DVMLEEPGYV EVGGRVSGQS WGSPASGYHV RVGTDGWELF SRDHAGAAEV
SLASGDESIE VDSWHEVILR MDGDTIGVFL DDRRLAEVQD TTQRTGNVAL SVSAWDNAQF
DDVRVVPTAG EPKFVSKDSM SASATSEHGF FQGWTYGAEH VIDDRPETEW SSAFDPPEGL
PQAVTVDLGS VQRIQALTYQ PRLDGNTNGM IRSYEVHLSA DGETFEEVAS GMWSADSSTK
VAAWPKQRAR YVRLIAADDD EGCGDATATA GELGVVQAKG PDLTTTPPAP PRSPLPDDAP
EEFDHLVSQA EMSATASSVH SDPYIPCRSV DGDTSTFWHS APAATGPLPA SVTLDLGQDR
DVQGLAYLPR QDGNPNGNIT SYDVEVSTDG EQFTTVTGGD WADDDTQKYA TWEPTSARYV
RLTASAGHFD VAAAAELHVA EAP
//
