ID   A0A329QI96_9ACTN        Unreviewed;       315 AA.
AC   A0A329QI96;
DT   10-OCT-2018, integrated into UniProtKB/TrEMBL.
DT   10-OCT-2018, sequence version 1.
DT   24-JAN-2024, entry version 16.
DE   SubName: Full=Electron transfer flavoprotein subunit alpha/FixB family protein {ECO:0000313|EMBL:RAW12060.1};
GN   ORFNames=DPM12_15345 {ECO:0000313|EMBL:RAW12060.1};
OS   Phytoactinopolyspora halophila.
OC   Bacteria; Actinomycetota; Actinomycetes; Jiangellales; Jiangellaceae;
OC   Phytoactinopolyspora.
OX   NCBI_TaxID=1981511 {ECO:0000313|EMBL:RAW12060.1, ECO:0000313|Proteomes:UP000250462};
RN   [1] {ECO:0000313|EMBL:RAW12060.1, ECO:0000313|Proteomes:UP000250462}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=YIM 96934 {ECO:0000313|EMBL:RAW12060.1,
RC   ECO:0000313|Proteomes:UP000250462};
RA   Tang S.-K.;
RT   "Phytoactinopolyspora halophila sp. nov., a novel halophilic actinomycete
RT   isolated from a saline soil in China.";
RL   Submitted (JUN-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: The electron transfer flavoprotein serves as a specific
CC       electron acceptor for other dehydrogenases. It transfers the electrons
CC       to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF
CC       dehydrogenase). {ECO:0000256|ARBA:ARBA00025649}.
CC   -!- COFACTOR:
CC       Name=FAD; Xref=ChEBI:CHEBI:57692;
CC         Evidence={ECO:0000256|PIRSR:PIRSR000089-1};
CC       Note=Binds 1 FAD per dimer. {ECO:0000256|PIRSR:PIRSR000089-1};
CC   -!- SUBUNIT: Heterodimer of an alpha and a beta subunit.
CC       {ECO:0000256|ARBA:ARBA00011355}.
CC   -!- SIMILARITY: Belongs to the ETF alpha-subunit/FixB family.
CC       {ECO:0000256|ARBA:ARBA00005817}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:RAW12060.1}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; QMIG01000017; RAW12060.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A329QI96; -.
DR   OrthoDB; 9770286at2; -.
DR   Proteomes; UP000250462; Unassembled WGS sequence.
DR   GO; GO:0009055; F:electron transfer activity; IEA:InterPro.
DR   GO; GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
DR   CDD; cd01715; ETF_alpha; 1.
DR   Gene3D; 3.40.50.620; HUPs; 1.
DR   Gene3D; 3.40.50.1220; TPP-binding domain; 1.
DR   InterPro; IPR029035; DHS-like_NAD/FAD-binding_dom.
DR   InterPro; IPR014730; ETF_a/b_N.
DR   InterPro; IPR001308; ETF_a/FixB.
DR   InterPro; IPR033947; ETF_alpha_N.
DR   InterPro; IPR014731; ETF_asu_C.
DR   InterPro; IPR014729; Rossmann-like_a/b/a_fold.
DR   PANTHER; PTHR43153; ELECTRON TRANSFER FLAVOPROTEIN ALPHA; 1.
DR   PANTHER; PTHR43153:SF1; ELECTRON TRANSFER FLAVOPROTEIN SUBUNIT ALPHA, MITOCHONDRIAL; 1.
DR   Pfam; PF01012; ETF; 1.
DR   Pfam; PF00766; ETF_alpha; 1.
DR   PIRSF; PIRSF000089; Electra_flavoP_a; 1.
DR   SMART; SM00893; ETF; 1.
DR   SUPFAM; SSF52402; Adenine nucleotide alpha hydrolases-like; 1.
DR   SUPFAM; SSF52467; DHS-like NAD/FAD-binding domain; 1.
PE   3: Inferred from homology;
KW   FAD {ECO:0000256|PIRSR:PIRSR000089-1};
KW   Flavoprotein {ECO:0000256|PIRSR:PIRSR000089-1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000250462}.
FT   DOMAIN          4..178
FT                   /note="Electron transfer flavoprotein alpha/beta-subunit N-
FT                   terminal"
FT                   /evidence="ECO:0000259|SMART:SM00893"
FT   BINDING         205
FT                   /ligand="FAD"
FT                   /ligand_id="ChEBI:CHEBI:57692"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR000089-1"
FT   BINDING         228..229
FT                   /ligand="FAD"
FT                   /ligand_id="ChEBI:CHEBI:57692"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR000089-1"
FT   BINDING         242..246
FT                   /ligand="FAD"
FT                   /ligand_id="ChEBI:CHEBI:57692"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR000089-1"
FT   BINDING         259..266
FT                   /ligand="FAD"
FT                   /ligand_id="ChEBI:CHEBI:57692"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR000089-1"
SQ   SEQUENCE   315 AA;  32500 MW;  13AADAC18C1A1453 CRC64;
     MPTILVLVDH ADGVVRKTTT ELLTLARRAG DPVAVFLGSG YESARETLAA YGATKVYVAE
     SSDFGTYLVA PEAEVLAQIA ATTEPAAILL PSSPDGKEIA GRLAVKLQSG IITDAVDIDA
     DLTTTQSVFA AEYSVTSRVT HGTPIITVKP NSAAPEPAAS TPEEEKVTVS ISDTAKRATV
     VERSERETTG RPDLAEAAVV VSGGRGTGGD FGPVEALADA LGGAVGASRA AVDSGWYPHA
     HQVGQTGQTV SPQLYIAAGI SGAIQHRAGM QTSKTIVAVD KDPEAPIFAM VDFGVVGDLH
     TVLPRATEEI TKRQG
//