ID A0A329RX65_9STRA Unreviewed; 1239 AA.
AC A0A329RX65;
DT 10-OCT-2018, integrated into UniProtKB/TrEMBL.
DT 10-OCT-2018, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE RecName: Full=PIPK domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=PC110_g14370 {ECO:0000313|EMBL:RAW29267.1};
OS Phytophthora cactorum.
OC Eukaryota; Sar; Stramenopiles; Oomycota; Peronosporales; Peronosporaceae;
OC Phytophthora.
OX NCBI_TaxID=29920 {ECO:0000313|EMBL:RAW29267.1, ECO:0000313|Proteomes:UP000251314};
RN [1] {ECO:0000313|EMBL:RAW29267.1, ECO:0000313|Proteomes:UP000251314}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=10300 {ECO:0000313|EMBL:RAW29267.1,
RC ECO:0000313|Proteomes:UP000251314};
RA Armitage A.D., Lysoe E., Nellist C.F., Harrison R.J., Brurberg M.B.;
RT "Draft genome of the strawberry crown rot pathogen Phytophthora cactorum.";
RL Submitted (JAN-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RAW29267.1}.
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DR EMBL; MJFZ01000438; RAW29267.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A329RX65; -.
DR STRING; 29920.A0A329RX65; -.
DR Proteomes; UP000251314; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0004930; F:G protein-coupled receptor activity; IEA:InterPro.
DR GO; GO:0052742; F:phosphatidylinositol kinase activity; IEA:InterPro.
DR GO; GO:0007166; P:cell surface receptor signaling pathway; IEA:InterPro.
DR GO; GO:0046488; P:phosphatidylinositol metabolic process; IEA:UniProtKB-UniRule.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR CDD; cd00139; PIPKc; 1.
DR Gene3D; 3.30.810.10; 2-Layer Sandwich; 1.
DR Gene3D; 3.30.800.10; Phosphatidylinositol Phosphate Kinase II Beta; 1.
DR Gene3D; 1.20.1070.10; Rhodopsin 7-helix transmembrane proteins; 1.
DR InterPro; IPR017981; GPCR_2-like_7TM.
DR InterPro; IPR000832; GPCR_2_secretin-like.
DR InterPro; IPR017452; GPCR_Rhodpsn_7TM.
DR InterPro; IPR027483; PInositol-4-P-4/5-kinase_C_sf.
DR InterPro; IPR002498; PInositol-4-P-4/5-kinase_core.
DR InterPro; IPR027484; PInositol-4-P-5-kinase_N.
DR InterPro; IPR023610; PInositol-4/5-P-5/4-kinase.
DR PANTHER; PTHR23086; PHOSPHATIDYLINOSITOL-4-PHOSPHATE 5-KINASE; 1.
DR PANTHER; PTHR23086:SF151; RPKA; 1.
DR Pfam; PF00002; 7tm_2; 1.
DR Pfam; PF01504; PIP5K; 1.
DR SMART; SM00330; PIPKc; 1.
DR SUPFAM; SSF81321; Family A G protein-coupled receptor-like; 1.
DR SUPFAM; SSF56104; SAICAR synthase-like; 2.
DR PROSITE; PS50262; G_PROTEIN_RECEP_F1_2; 1.
DR PROSITE; PS50261; G_PROTEIN_RECEP_F2_4; 1.
DR PROSITE; PS51455; PIPK; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|PROSITE-ProRule:PRU00781};
KW Kinase {ECO:0000256|PROSITE-ProRule:PRU00781};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|PROSITE-ProRule:PRU00781};
KW Reference proteome {ECO:0000313|Proteomes:UP000251314};
KW Transferase {ECO:0000256|PROSITE-ProRule:PRU00781};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 125..145
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 151..174
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 186..206
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 226..253
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 265..287
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 338..362
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 383..403
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 151..281
FT /note="G-protein coupled receptors family 2 profile 2"
FT /evidence="ECO:0000259|PROSITE:PS50261"
FT DOMAIN 165..438
FT /note="G-protein coupled receptors family 1 profile"
FT /evidence="ECO:0000259|PROSITE:PS50262"
FT DOMAIN 796..1192
FT /note="PIPK"
FT /evidence="ECO:0000259|PROSITE:PS51455"
FT REGION 1..32
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 474..499
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 524..592
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 825..850
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 13..32
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 527..543
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 553..592
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 825..848
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1239 AA; 136782 MW; 72B6C3311C16D734 CRC64;
MPAPRRALRP SSPAPDSDTN CTSPQYQAVS TPTRTSAQEF DLLVDEVVRS RSHSHALSAI
LGANSQVSAS ASTSLDWRPS SQAQLQIGNS ATQLQREQVA EGEEKTELPV RLVNWRRQRR
HWKKVLFWVG AVGVFIGFFA LSFAAPKQVQ TLAPIVLGAG LSLVSTLLVL VSFLRRRRLR
RRPNELLAFV ALSEFGLAAL TMIHVLTLCS AEDGGCRPMG LTTCSIAASL EMFMLLAGVG
WFGAAILHLF VSVSNPFASY KRQLVLYHLV VWGLSLIASI ATPLILFSGH TQDKFPLSDA
EACRMVALIL PLLPSDAGES VANRRRRLAQ WQELNLEFWG LLIAIVVLVV VAAQLSLVVG
WWRSNSGTII ALKARRRLMK RMTIYVHALN AMWLVLLVVF FVYRSNTSAL DYVQVEGVAQ
PTDGGMNFLN AFFHFVLTGK GFVTGVVWLS VNKPCCAFGL VFCGLHQCKD SDDSPSLGQS
ASGSSQSASF SGSSNREIRG QRANQAAILS ETVMSMEAGV LAPHETPMLS PSSTVSNFEA
HESVRESSAL RPPEQHSLPT LSSVLEPASM ARSSRSSSSS YEASTVESYE ASQNNETLQR
EIIYYTVCGI TKAIIRSAER ARSSSVNATE SGVVSGEENV ANARDRDGGL VETTLFVGAE
RDSTLVNSSF ISHVQSVMIL SSPRAYCEPR VSLPVASLRR SLAAFDEERV YIPRPTSFTA
ASTLEYSSIW RQPHLQHSQN QENPSPQSAR LSLTASSVMF HTFQQTPGRF SLYPVSQVPF
ELFEQEIELQ STRSSVDEPV EGRSTRSAVF AGLRRTATSA FSQGRGVFRS RSGSTEPTDS
SNSTMTREFL PDDPKPKVFV DYAPREFRAI RLAFGLSDEK YLASFRTTAK ERVSAGSSGA
FMFFSGDNSL LVKSLKEKEC RALVDMAPAY ARYLTANPHS RLIRFFGCHR VRLYGRNFYF
AVMSNVLHSE RHTATITEKY DVKGSWVDRR ARRPQRGDRV TCAECDATYT FDEGDTPVDS
DNDRVSTDDH TVPQFPFHVH RPDVVFKDLD LERSLQLPRH IAVHLHSQIV SDCEFLRDIG
IMDYSLLIGI HKCHFRTPRP GNANGIGTST DFDDVFNREL HLDGPNSGVN LAPLGDNEVY
FVGIIDILQQ WDWEKQFEKA GKVLLGKSAR GISAVAPTAY CRRFQARCAQ ILLGGPAPEN
LDPDCEVDSK AVNVKETKSR PDSKNIKEMA MTNLISDKA
//
