ID A0A329S6K9_9STRA Unreviewed; 160 AA.
AC A0A329S6K9;
DT 10-OCT-2018, integrated into UniProtKB/TrEMBL.
DT 10-OCT-2018, sequence version 1.
DT 24-JAN-2024, entry version 17.
DE RecName: Full=Glycine cleavage system H protein {ECO:0000256|RuleBase:RU364055};
GN ORFNames=JG687_00006402 {ECO:0000313|EMBL:KAG6963655.1}, PC110_g12345
GN {ECO:0000313|EMBL:RAW31318.1}, PC113_g11148
GN {ECO:0000313|EMBL:KAG2856931.1}, PC115_g13185
GN {ECO:0000313|EMBL:KAG2909667.1}, PC117_g11703
GN {ECO:0000313|EMBL:KAG2937401.1}, PC118_g13942
GN {ECO:0000313|EMBL:KAG2975425.1}, PC129_g15403
GN {ECO:0000313|EMBL:KAG3213672.1};
OS Phytophthora cactorum.
OC Eukaryota; Sar; Stramenopiles; Oomycota; Peronosporales; Peronosporaceae;
OC Phytophthora.
OX NCBI_TaxID=29920 {ECO:0000313|EMBL:RAW31318.1, ECO:0000313|Proteomes:UP000251314};
RN [1] {ECO:0000313|EMBL:RAW31318.1, ECO:0000313|Proteomes:UP000251314}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=10300 {ECO:0000313|EMBL:RAW31318.1,
RC ECO:0000313|Proteomes:UP000251314};
RA Armitage A.D., Lysoe E., Nellist C.F., Harrison R.J., Brurberg M.B.;
RT "Draft genome of the strawberry crown rot pathogen Phytophthora cactorum.";
RL Submitted (JAN-2018) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:KAG2856931.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=15-7 {ECO:0000313|EMBL:KAG2856931.1}, 4032
RC {ECO:0000313|EMBL:KAG2909667.1}, 4040 {ECO:0000313|EMBL:KAG2937401.1},
RC P415 {ECO:0000313|EMBL:KAG2975425.1}, and P421
RC {ECO:0000313|EMBL:KAG3213672.1};
RA Armitage A.D., Nellist C.F., Bates H., Vickerstaff R.J., Harrison R.J.;
RT "Effector identification in a new, highly contiguous assembly of the
RT strawberry crown rot pathogen Phytophthora cactorum.";
RL Submitted (OCT-2018) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:KAG6963655.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=NZFS 3830 {ECO:0000313|EMBL:KAG6963655.1};
RA Mcdougal R., Panda P., Williams N., Studholme D.J.;
RT "Phytophthora aleatoria, a newly-described species from Pinus radiata is
RT distinct from Phytophthora cactorum isolates based on comparative
RT genomics.";
RL Submitted (JAN-2021) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: The H protein shuttles the methylamine group of glycine from
CC the P protein to the T protein. {ECO:0000256|RuleBase:RU364055}.
CC -!- COFACTOR:
CC Name=(R)-lipoate; Xref=ChEBI:CHEBI:83088;
CC Evidence={ECO:0000256|RuleBase:RU364055};
CC Note=Binds 1 lipoyl cofactor covalently.
CC {ECO:0000256|RuleBase:RU364055};
CC -!- SUBUNIT: The glycine cleavage system is composed of four proteins: P,
CC T, L and H. {ECO:0000256|RuleBase:RU364055}.
CC -!- SUBCELLULAR LOCATION: Mitochondrion {ECO:0000256|ARBA:ARBA00004173,
CC ECO:0000256|RuleBase:RU364055}.
CC -!- SIMILARITY: Belongs to the GcvH family. {ECO:0000256|ARBA:ARBA00009249,
CC ECO:0000256|RuleBase:RU364055}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RAW31318.1}.
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DR EMBL; RCMG01000311; KAG2856931.1; -; Genomic_DNA.
DR EMBL; RCMI01000464; KAG2909667.1; -; Genomic_DNA.
DR EMBL; RCMK01000308; KAG2937401.1; -; Genomic_DNA.
DR EMBL; RCML01000494; KAG2975425.1; -; Genomic_DNA.
DR EMBL; RCMV01000710; KAG3213672.1; -; Genomic_DNA.
DR EMBL; JAENGZ010000261; KAG6963655.1; -; Genomic_DNA.
DR EMBL; MJFZ01000328; RAW31318.1; -; Genomic_DNA.
DR STRING; 29920.A0A329S6K9; -.
DR Proteomes; UP000251314; Unassembled WGS sequence.
DR Proteomes; UP000688947; Unassembled WGS sequence.
DR Proteomes; UP000697107; Unassembled WGS sequence.
DR Proteomes; UP000735874; Unassembled WGS sequence.
DR Proteomes; UP000736787; Unassembled WGS sequence.
DR Proteomes; UP000760860; Unassembled WGS sequence.
DR Proteomes; UP000774804; Unassembled WGS sequence.
DR GO; GO:0005960; C:glycine cleavage complex; IEA:UniProtKB-UniRule.
DR GO; GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
DR GO; GO:0019464; P:glycine decarboxylation via glycine cleavage system; IEA:UniProtKB-UniRule.
DR CDD; cd06848; GCS_H; 1.
DR Gene3D; 2.40.50.100; -; 1.
DR HAMAP; MF_00272; GcvH; 1.
DR InterPro; IPR003016; 2-oxoA_DH_lipoyl-BS.
DR InterPro; IPR000089; Biotin_lipoyl.
DR InterPro; IPR002930; GCV_H.
DR InterPro; IPR033753; GCV_H/Fam206.
DR InterPro; IPR017453; GCV_H_sub.
DR InterPro; IPR011053; Single_hybrid_motif.
DR NCBIfam; TIGR00527; gcvH; 1.
DR PANTHER; PTHR11715; GLYCINE CLEAVAGE SYSTEM H PROTEIN; 1.
DR PANTHER; PTHR11715:SF3; GLYCINE CLEAVAGE SYSTEM H PROTEIN, MITOCHONDRIAL; 1.
DR Pfam; PF01597; GCV_H; 1.
DR SUPFAM; SSF51230; Single hybrid motif; 1.
DR PROSITE; PS50968; BIOTINYL_LIPOYL; 1.
DR PROSITE; PS00189; LIPOYL; 1.
PE 3: Inferred from homology;
KW Lipoyl {ECO:0000256|ARBA:ARBA00022823, ECO:0000256|PIRSR:PIRSR617453-50};
KW Mitochondrion {ECO:0000256|RuleBase:RU364055};
KW Reference proteome {ECO:0000313|Proteomes:UP000251314};
KW Transit peptide {ECO:0000256|ARBA:ARBA00022946,
KW ECO:0000256|RuleBase:RU364055}.
FT DOMAIN 53..135
FT /note="Lipoyl-binding"
FT /evidence="ECO:0000259|PROSITE:PS50968"
FT MOD_RES 94
FT /note="N6-lipoyllysine"
FT /evidence="ECO:0000256|PIRSR:PIRSR617453-50"
SQ SEQUENCE 160 AA; 17214 MW; A39A87B9E24309C3 CRC64;
MALRVLSQTL RARALKSATP AAWRATSQRP AGLAFFSTKY TPQHEYVTLN GKEGTIGITD
FAQNSLGDVV YVDLPSVGDK FAKGDAFGAV ESVKAASDVY TPAAGTVTAV NEDLAESPNL
VNDEAMTGGW FIKLELDDVS DLDDLLDEAA YKEHCENEEH
//
