ID A0A329SPW4_9STRA Unreviewed; 4557 AA.
AC A0A329SPW4;
DT 10-OCT-2018, integrated into UniProtKB/TrEMBL.
DT 10-OCT-2018, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Dynein heavy chain 2, axonemal {ECO:0000313|EMBL:RAW37622.1};
GN ORFNames=PC110_g6132 {ECO:0000313|EMBL:RAW37622.1}, PC113_g1954
GN {ECO:0000313|EMBL:KAG2867463.1}, PC115_g1378
GN {ECO:0000313|EMBL:KAG2942493.1}, PC117_g2000
GN {ECO:0000313|EMBL:KAG2953417.1}, PC118_g1829
GN {ECO:0000313|EMBL:KAG2997518.1}, PC129_g2896
GN {ECO:0000313|EMBL:KAG3226533.1};
OS Phytophthora cactorum.
OC Eukaryota; Sar; Stramenopiles; Oomycota; Peronosporales; Peronosporaceae;
OC Phytophthora.
OX NCBI_TaxID=29920 {ECO:0000313|EMBL:RAW37622.1, ECO:0000313|Proteomes:UP000251314};
RN [1] {ECO:0000313|EMBL:RAW37622.1, ECO:0000313|Proteomes:UP000251314}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=10300 {ECO:0000313|EMBL:RAW37622.1,
RC ECO:0000313|Proteomes:UP000251314};
RA Armitage A.D., Lysoe E., Nellist C.F., Harrison R.J., Brurberg M.B.;
RT "Draft genome of the strawberry crown rot pathogen Phytophthora cactorum.";
RL Submitted (JAN-2018) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:KAG2867463.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=15-7 {ECO:0000313|EMBL:KAG2867463.1}, 4032
RC {ECO:0000313|EMBL:KAG2942493.1}, 4040 {ECO:0000313|EMBL:KAG2953417.1},
RC P415 {ECO:0000313|EMBL:KAG2997518.1}, and P421
RC {ECO:0000313|EMBL:KAG3226533.1};
RA Armitage A.D., Nellist C.F., Bates H., Vickerstaff R.J., Harrison R.J.;
RT "Effector identification in a new, highly contiguous assembly of the
RT strawberry crown rot pathogen Phytophthora cactorum.";
RL Submitted (OCT-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RAW37622.1}.
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DR EMBL; RCMG01000025; KAG2867463.1; -; Genomic_DNA.
DR EMBL; RCMI01000017; KAG2942493.1; -; Genomic_DNA.
DR EMBL; RCMK01000025; KAG2953417.1; -; Genomic_DNA.
DR EMBL; RCML01000025; KAG2997518.1; -; Genomic_DNA.
DR EMBL; RCMV01000055; KAG3226533.1; -; Genomic_DNA.
DR EMBL; MJFZ01000108; RAW37622.1; -; Genomic_DNA.
DR STRING; 29920.A0A329SPW4; -.
DR Proteomes; UP000251314; Unassembled WGS sequence.
DR Proteomes; UP000697107; Unassembled WGS sequence.
DR Proteomes; UP000735874; Unassembled WGS sequence.
DR Proteomes; UP000736787; Unassembled WGS sequence.
DR Proteomes; UP000760860; Unassembled WGS sequence.
DR Proteomes; UP000774804; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0030286; C:dynein complex; IEA:UniProtKB-KW.
DR GO; GO:0005874; C:microtubule; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0045505; F:dynein intermediate chain binding; IEA:InterPro.
DR GO; GO:0051959; F:dynein light intermediate chain binding; IEA:InterPro.
DR GO; GO:0008569; F:minus-end-directed microtubule motor activity; IEA:InterPro.
DR GO; GO:0007018; P:microtubule-based movement; IEA:InterPro.
DR Gene3D; 1.10.287.2620; -; 1.
DR Gene3D; 1.10.472.130; -; 1.
DR Gene3D; 1.10.8.1220; -; 1.
DR Gene3D; 1.10.8.710; -; 1.
DR Gene3D; 1.20.1270.280; -; 1.
DR Gene3D; 1.20.58.1120; -; 1.
DR Gene3D; 1.20.920.20; -; 1.
DR Gene3D; 1.20.920.30; -; 1.
DR Gene3D; 3.10.490.20; -; 1.
DR Gene3D; 6.10.140.1060; -; 1.
DR Gene3D; 1.20.140.100; Dynein heavy chain, N-terminal domain 2; 1.
DR Gene3D; 3.20.180.20; Dynein heavy chain, N-terminal domain 2; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 5.
DR Gene3D; 1.10.8.720; Region D6 of dynein motor; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR035699; AAA_6.
DR InterPro; IPR035706; AAA_9.
DR InterPro; IPR041658; AAA_lid_11.
DR InterPro; IPR042219; AAA_lid_11_sf.
DR InterPro; IPR026983; DHC_fam.
DR InterPro; IPR041589; DNAH3_AAA_lid_1.
DR InterPro; IPR042222; Dynein_2_N.
DR InterPro; IPR043157; Dynein_AAA1S.
DR InterPro; IPR041466; Dynein_AAA5_ext.
DR InterPro; IPR041228; Dynein_C.
DR InterPro; IPR043160; Dynein_C_barrel.
DR InterPro; IPR024743; Dynein_HC_stalk.
DR InterPro; IPR024317; Dynein_heavy_chain_D4_dom.
DR InterPro; IPR004273; Dynein_heavy_D6_P-loop.
DR InterPro; IPR013602; Dynein_heavy_linker.
DR InterPro; IPR013594; Dynein_heavy_tail.
DR InterPro; IPR042228; Dynein_linker_3.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR10676:SF183; DYNEIN AXONEMAL HEAVY CHAIN 2; 1.
DR PANTHER; PTHR10676; DYNEIN HEAVY CHAIN FAMILY PROTEIN; 1.
DR Pfam; PF12774; AAA_6; 1.
DR Pfam; PF12775; AAA_7; 1.
DR Pfam; PF12780; AAA_8; 1.
DR Pfam; PF12781; AAA_9; 1.
DR Pfam; PF17857; AAA_lid_1; 1.
DR Pfam; PF18198; AAA_lid_11; 1.
DR Pfam; PF08385; DHC_N1; 1.
DR Pfam; PF08393; DHC_N2; 1.
DR Pfam; PF17852; Dynein_AAA_lid; 1.
DR Pfam; PF18199; Dynein_C; 1.
DR Pfam; PF03028; Dynein_heavy; 1.
DR Pfam; PF12777; MT; 1.
DR SMART; SM00382; AAA; 2.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 4.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Cytoskeleton {ECO:0000256|ARBA:ARBA00023212};
KW Dynein {ECO:0000256|ARBA:ARBA00023017};
KW Microtubule {ECO:0000256|ARBA:ARBA00022701};
KW Motor protein {ECO:0000256|ARBA:ARBA00023175};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000251314}.
FT DOMAIN 1904..2041
FT /note="AAA+ ATPase"
FT /evidence="ECO:0000259|SMART:SM00382"
FT DOMAIN 2518..2664
FT /note="AAA+ ATPase"
FT /evidence="ECO:0000259|SMART:SM00382"
FT REGION 966..1014
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 3118..3152
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 3177..3226
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 3341..3417
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 3653..3680
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 966..984
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 4557 AA; 516602 MW; F688CCBD10703CAD CRC64;
MSSFEDVELI AQWIRERITL PGYQPKAWTS ADLATVKEFA ESTGVPALFL TLQNDSLVVM
TTAPRHFSSI MYFVKNGQTL VTPANIKDAL QYGTVEKDAI SSLLHLMNSY YLQRLQANKS
WPESVQKEFT GQFFRFMSSL TETVSRGCGK TVLYLPPVNP DKFNYKDKDL VQQLESTVIH
WTRQIKEVIN NQDNAHDAEG AGPLEEIKFW EHRTQDLSGI TDQLNRDGVK EIVEILRAAK
SSYLQPFETL SQIIKQGSTE ANDNLRFLQK LSPVCEDIAR AQPDEIPLLL PKLLNFIRLI
WMYSRHYNTE DRITSLLRKV SNEIIIVCCK KISLPDVFDG NVEASIHHLE QSIQCGVSWK
QIYRKASHAV NTTAPSPDRR WNFDETGIFA QIDAFVQRCR ELLEVCEGQT QFARKGKDGK
REDLPTFGGN RGMDIVKSLR GIEAQFEGHV DRLRQLDYDI LDVKNTSWHS DFNSFKNGMK
DLEAMTQNVI NGAFESVSTV AAGVDMIGSF HKIAQREAIK RCVEKRTIDI FGMFKANIAS
IRNLFEKNKQ TPLLSPTEPQ FAGAALWARS LLLRATDDLV RLQELVDPSN AAECDESQNA
YDGLRLVINE YIQRKYHDWI EDLNTLGNSN MNSRLENPLM TKTGADPDAA PASVNLNTHN
KDANALQNTE KTLIGRAKKG FLHCNFDRPL LNLFAEVHYW QYFNGEIQIP YMAHDICNQK
EQLRVLREHV MLVVRDYNRI LLDLSSTERR LFEDIIRKLD RRIQPGLQKL TWVSKGIVEW
YVADCRKHCE TTYKIVQEFQ ENKDIVMKNC KMISGLMHIF IERNTIYDDG VFEAKQVIHR
KTIEKQLREA YQTISSTMTA TYEHFASGPP EVQREWNRFV ERSDKMLEDA LRQSVKKSLQ
ELSKAINGDA KTDPRPLFRI HVVLEDNKVE FKPFMADLTQ MVNTVAKEIF NVISVVPRLV
ASLPQHHGNN QANADNSTAN GAPADGKSAS KGGEEVRAPV TASGEPTGNP DEALSAVDTP
EKVEAPPPVV NNFYQSIFND EEILKVLVHI MNGMSSSATE LQKYLGYWDK YKLVWNQDKQ
AFIRRYAKAN RPLQQFRADI ERYREQQVSI QNEDLTNTIN FIQIDTNFLK ASLVEHTVQW
IGKLTGLLNQ TAHGELKELM NMMKDNTQKL QIKPLNLDHL SESIHLLQDI KEGMPGVVAR
FEPLQHKYDL LAEFDVQTTD EEQRDLANLK SNWETYEAML VDANTMLQKC KVSMKQSLQD
SVADLNNIMS ELRTEAEATL PYSGEQQSKA AHQILAEFEK KMEATRSRQN ALKKGLEIFG
IEESKNDGFV QTEKELELLQ QIWALTDEWG VVWASWKNKV FYEIEVETME STAAQFFKKV
VKYGKDMKNW AVWSSMKTKI EQFRQTLPLI QDLKSPALRA RHWAQLKEEM GKTFDTESTS
FTLERVFSLG FHLYAEFIST LSSNAGKELS IEQTLDAIEK RWATIDVDIT EYKGVYYKIR
SADDLFTALE DDQVQLSTMK ASPFFGSFDT RILYWEKALS HLSDVIETLL GVQRCWIYLE
SIFMASEDIR KQLPLESQLF DEVNTAYCRV TEGMAKTKNA LQATQEAGVL ETLVTMQEKL
DQIQKCLDQY LETKRMLFPR FYFLSNDDLL EILGHQKDPD QVQKHIKKCF EAIKTLNLIP
PGARGNTTFE ALGMNSPCGE QVMFASNVVV AGAVEGWLLR IEAAMINTLE KIFAQCIVGY
KGKKEKWIKD FPGQLLITCG QTAWTNECIK ALNEVAKGEK KALKQLKKKW ISYLNKLADM
VRGQLSATDR RKVVAVITIE IHSRDVIDRL VKQNCKSVND FDWLMQLRFY FNKDLGESGI
CEVKQTVTSL QYSYEYQGNN GRLVITPLTD RCVLTMTTAL HLNRGGNPLG PAGTGKTETV
KDLGKNLAKY VIVFNCSDGL DYKSVGRMFA GLVQSGGWGC FDEFNRIEIE VLSVVAQQVL
TIMQALTARS TQVMFLGSMM RVNFNMGIFI TMNPGYAGRT ELPDNLKALM RPCAMMVPDL
ALIAEVMLQA EGFRDAKVLA KKTTTLYGLM IQQLSKQDHY DFGLRSLKAV LNMAGTLKRE
DPNLQEENIL LRALRDMNMP KFIREDAVLF RLLLGDLFPS IELPVTDYGK LQGNIEQALL
ETKLQVHPVI VFKTIQLYES QVTRHCNMIV GQTMAGKTTI WKTLMAAKTS LAKEGVPGYM
PVRVQVLNPK SISLNEIYGV YDLSTFEWID GILSAIFRNL AADEKAEEKW IMLDGPVDTL
WIESMNSVMD DNKVLTLING DRISMSPSMA LMFEVQDLAV ASPATVSRAG MVYMDVEDLG
WHPFIQTWLA TTIHIQEERD VLQTLFDKYM EKVLRFKTSE VTELIPVTTF NSVKSFCNLY
NALATAENGV DLAACGDKFA VTVEKWFLFC MTWSVMAAAN EEGRKKFDFF LRDIDSVYPP
LKTAYDFFVE PTSREFKLWD EKLPPNFRIA PNTPFHKIMV PTIDTLRYGY LLQTMLTAGI
HTLLVGETGV GKTTVIEREI EALSDAYNVL VMNFSSATSS ATTQDMIENV MEKRSLNRFG
PVGGRKLVTF IDDMNMPTKD LFGSQPPLEL LRQWVDYSCW YDRKKQTLKY FIDMQFVAAM
GPPGGGRSVI SSRFQSRFNL INMTIPEQAQ LKRIFETMLV PKLAEFDDEV KPLGVPLVSA
TIQLYQNVLE QFLPTPANCH YLFNLRDMAR VIQGLLLSDK HTVASRDGML RLWMHESLRV
FSDRLTSYED RQSFKRKLDD LLGVHFQTDW GRLLSSAPEQ LKENGPLFTY IFSTTPGSDE
GSARYAEVMD MKMLKSFVEE QLENHNAEPG FVPMNLVMFS DALMHILRIH RQLMTMRGNL
LLVGVGGSGR QSLTKLAAFM GGFKVFQIEV GKNYRSFEFH EDIKKLYTQV GLQQQKTVFL
FSDTQIKNES FVEDLNNILS SGEIPGLFEK DEQAGILDGV RLRARAQGIR ETKESLWNFF
ISEVRRNLHV VLAFSPIGKG FCNRCRQFPS LVNNTNIDWF NEWPLDALQE VGMKFLEEKN
VALEVQRPKI AAVFAVVHSS VMLASSQVLA RMKRHNYVTP TNYLSLVTGY VELLSEKAAT
IRDTRDKLKN GLAKLEESRL QVEEMSKQLE QRKIVVAQKN KDCSDLLVVI VSERRVADEQ
RKQVEADSER IGKEEAETKK IADDAQKDLD EALPALQRAM QEVENLDKKA IAEVKVYTQP
PEAVSMVMCA VMILFGLPPT WASAKTKMND VSFLQQIKTF DKDSIRDKTV TALKKYTSKP
TFNSDVVRKV SSAAGALCSW VLAMECYSGV FRVVAPKKEV LRKSQQALAV KQKDLQVAKE
KLQEVTEKVE ALKNQYDTSV SEKNALREEA ELLELKLSRA EQLVKGLAGE RERWEASIAD
KNASLQNVVG DALVAAAFIS YAGPFDTFYR GSLVDTWMNR VTQQALPLSP KFTFIDFLAD
PTDVRSWNAH GLPRDPLSTE NGVITTRGKR WPLMIDPQGQ ANKWIKAMEG TRLEVVDPMM
KDLLRKLENG IRFGSPVLMQ DILEELDPSL EPVLTKSIIK VGNREVLRLG DKELDYNREF
RFYLTTKLHN PHYTPEVSTK TTIVNFVVKE QGLEAQLLGI AVQLEEPALE EQKSDLVMRV
AAAKKKLIDL ENEILRLLSA AKGSLLDDEQ LVTTLNASKT TSEEVSMQLV ISEETEKKID
AARMGYARVA LRSSTLYFVL NDMTSVDPMY QFSLDAYVAL FQDSIVKSRS LKNQGALSEE
LTERINAIND YHTYAVYAYA CRGLFERHKL LFSLQMCARV LQSVNKLPHD EYDFLLKGGN
VLAQEEKVAN VANEFLSDGS WASIVELNKL SAFHGIISSF EQTLKGWKSW YQSSTPEIEA
LPGDWEGKCN ELQRMLLLRC VRPDRLSIQA ARFTATHLGA QFVDPPPFDL KAIYDTSNYK
TPLIFVLSPG VDPTNSLIAL AESLHKTVEN CALGQGQASV AEAMLARGLD AGNWVFLANC
HLMLSWAPTL EKLIDNFCAA APAPAGPINP QFRLWLTSSP NPKFPIAILQ RGIKMTTEPP
RGLKANLIRL YNTITPDKFA RCRQVKKYKR LLFCLCWFHS LLLERRKFNN LGWNIPYDFN
ESDFAISEDV LAIYLDEYED TPWDALKYLI AQANYGGRVT DDWDRRLMLV YISQFFSENV
LSVDNMLLSD SEYYFVPDDG ELSSYTEYIR QLPLDDPPAA FGQHPNAQIA SQIDDGRELL
ATILSLQALD VAEGGSGNDD TVLGLLQTLR ETVPDVFDLA NIKAGLSARS DPDALKTVLM
QELERYNKLL ATINSSARAL EKGIQGSVVI TPELEAVYNA LLIGAVPQAW SFCYPSLKPL
GPWTQDLKLR CEQMDRWANQ AQPAVFWLTG FTYPTGFLTA LLQTAARKNG LAIDSLNWEF
IVLNQGENAL PTGPKDGAYI KGLILEGARW DFDHDCLAEP HPMELHCGMP ILHFRPVEAK
KKSAKGLYSC PLYMYPLRTG TRERPSFMIA VDLKVGPGKT PDLWTRRGTA LLLSLST
//
