ID A0A329SQZ8_9STRA Unreviewed; 2043 AA.
AC A0A329SQZ8;
DT 10-OCT-2018, integrated into UniProtKB/TrEMBL.
DT 10-OCT-2018, sequence version 1.
DT 24-JAN-2024, entry version 17.
DE RecName: Full=1,3-beta-glucan synthase {ECO:0000256|ARBA:ARBA00012589};
DE EC=2.4.1.34 {ECO:0000256|ARBA:ARBA00012589};
GN ORFNames=PC110_g5744 {ECO:0000313|EMBL:RAW38022.1};
OS Phytophthora cactorum.
OC Eukaryota; Sar; Stramenopiles; Oomycota; Peronosporales; Peronosporaceae;
OC Phytophthora.
OX NCBI_TaxID=29920 {ECO:0000313|EMBL:RAW38022.1, ECO:0000313|Proteomes:UP000251314};
RN [1] {ECO:0000313|EMBL:RAW38022.1, ECO:0000313|Proteomes:UP000251314}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=10300 {ECO:0000313|EMBL:RAW38022.1,
RC ECO:0000313|Proteomes:UP000251314};
RA Armitage A.D., Lysoe E., Nellist C.F., Harrison R.J., Brurberg M.B.;
RT "Draft genome of the strawberry crown rot pathogen Phytophthora cactorum.";
RL Submitted (JAN-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=[(1->3)-beta-D-glucosyl](n) + UDP-alpha-D-glucose = [(1->3)-
CC beta-D-glucosyl](n+1) + H(+) + UDP; Xref=Rhea:RHEA:21476, Rhea:RHEA-
CC COMP:11146, Rhea:RHEA-COMP:14303, ChEBI:CHEBI:15378,
CC ChEBI:CHEBI:37671, ChEBI:CHEBI:58223, ChEBI:CHEBI:58885; EC=2.4.1.34;
CC Evidence={ECO:0000256|ARBA:ARBA00000192};
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the glycosyltransferase 48 family.
CC {ECO:0000256|ARBA:ARBA00009040}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RAW38022.1}.
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DR EMBL; MJFZ01000098; RAW38022.1; -; Genomic_DNA.
DR STRING; 29920.A0A329SQZ8; -.
DR Proteomes; UP000251314; Unassembled WGS sequence.
DR GO; GO:0000148; C:1,3-beta-D-glucan synthase complex; IEA:InterPro.
DR GO; GO:0003843; F:1,3-beta-D-glucan synthase activity; IEA:UniProtKB-EC.
DR GO; GO:0006075; P:(1->3)-beta-D-glucan biosynthetic process; IEA:InterPro.
DR InterPro; IPR026899; FKS1-like_dom1.
DR InterPro; IPR003440; Glyco_trans_48.
DR PANTHER; PTHR12741:SF29; 1,3-BETA-GLUCAN SYNTHASE COMPONENT FKS1-RELATED; 1.
DR PANTHER; PTHR12741; LYST-INTERACTING PROTEIN LIP5 DOPAMINE RESPONSIVE PROTEIN DRG-1; 1.
DR Pfam; PF14288; FKS1_dom1; 1.
DR Pfam; PF02364; Glucan_synthase; 1.
DR SMART; SM01205; FKS1_dom1; 1.
PE 3: Inferred from homology;
KW Glycosyltransferase {ECO:0000256|ARBA:ARBA00022676};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000251314};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 699..718
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 724..743
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1558..1580
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1611..1629
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1636..1654
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1700..1719
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1842..1860
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1875..1896
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1916..1933
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1939..1958
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1978..1996
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 249..352
FT /note="1,3-beta-glucan synthase component FKS1-like"
FT /evidence="ECO:0000259|SMART:SM01205"
FT REGION 183..205
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 830..856
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 839..856
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2043 AA; 233543 MW; E146EDD7B8015B71 CRC64;
MNRRGHGNGN GNGSEREGSS VGLMTEALEM QRQMCDEAMS LVNAGVAMQN ASPPNVAEAE
RKLTRAVDIM EQALSIRYRS ADEKDAADRL NNKMMRYVKM IKSQRAKSVV GGGPKGRNLI
KHNILEMERL PEVYTPVLQL LNNSNQLGDI CESLKRTFGF QESSVLNQKE HLLLLLTNFK
EQSGQDDGKK KKKKKKQDDT ETIDDYLRQR DPQLEMDLAN KGITRLHGRV FANYKKWCKY
VSQKPKFSSD LLVDITLFFL IWGEAANFRQ MPECLCFLLH TMLPKVNSGG NEEPGTFLAN
TIRPMYAELR RDSDKKTSKG ARAPHREIRN YDDFNEFFWT KKSLKYDYTN IGEAFANYDK
KGRPKIVKKT FSETRSWTRA IISFRRIFLM NCALFLATLG FSIDMVLLCP DSAIMYGEDV
QPSSETGVLE ILGKKYAATT GSSSVVNTDD SLSDDINTDS GAGSQCLYAK LATCLGVQYF
TSASDTFGTL PQDFKELLEL VPFTDCVEKT VGRCKCYHDF IDDCFNDSGK ADEVSTEGSV
ASITYDQSVC APAWMAQVNS ILDDEGDGLL NCGSCQIDIT SLAKKPTRIM DMLQGLIDFG
RNDKGPMALL GGAAMIGLVC VCELQNRFFS GIGMGFVGRS MPVPMKTYCR YTCFWIVLYL
VKLTFDYQFV VKTLVETTLF VYSAKSTDYL QYSHFMLQIT YHNIVYILFL WVPAWMVFLY
DAQIFYSVLS VIYGSFAGFN LRIGELRSFR ILRLTFKSIP GVFNRKLVPN IVEEKAKKKK
KKNKKNKNDK DEMAMPLRRF ERISMSQGAK PLTVKTQKYS SLLEQRDDDD VYSEMKTPNG
TDEDMSSQSS RSSNIGSITG VSGAEFERTI PFAMAWNRCL TSLREADVIS DRELNVLSYL
IDSKDTVGRK LYPPAFLTAG KLDESIDIVL ECSALYEKLK TDKKKKDKVL QKIETTMRER
LTKDDLRVES ILGSYKFSSQ VLRILLGEEH KELDDCYNFI EEMASHQQIL KGLKLDNLYL
CRAAAAELMK SILEVPKKST ETSIKFQRAL YKVIDSVESV INCLKMVLAK QENLVQMLND
TPLKPNSFFF PGDSQHYASL QLQKIVNDEA ALDIVSRAYQ LLTVDNFDAE PRSEEGRRRL
RFFANSLFMD MPEAKPIRKI RSLTVSTPYY NEIVMYSIKD LTAQNDDCIK LLYYLQTIYP
FEWENLLERI QAKDMNEALK KNPEEVQLWA SYRGQTLART VRGMMYNAEA IRFLHWLEIG
ENEPMHQVTC SCNKCCKLNE MVALKFNYVC TCQIYGKQKD EQKQQAQDID FLLRKHLNLR
VAYVDGPKKV KDGPPKFFSV LIRSQDEKIV EIYRVELPGN PIVGEGKPEN QNHAIIFSRG
ELLQCIDMNQ DGYLEEALKM PNLLSTMDRG TEKRPLTIIG FREHVFTGGV SNLASFMSIQ
ELSFVSLGQR MLAINHVRQH YGHPDIFDKL FAMGCGGTAK ASKGVNLSED IFAGFNSTLR
GGRVSHEEFI QVGKGRDVGM QQLALFEAKL SSGAGECVIS RDAMRMASRL DFFRLHSWFY
GNLGWYFTQT MTVVGVYFFI YGKVYMALSG MDSFFLEKGG LGIGGTLNTS WAFQFGFLLV
VPVVAVVGVE QGFRHGVTYL IWNIMTLGPL FFTFQMGTRM HYFDRTLIHG GAKYRATGRG
FTIKHEKFAE LFRFYAFSHF YRGVELLFLL LMFYAYGTFS WCNCSWRLDA DFYNNVEPTD
LEWRTRCYDD HYQSCVLPTN QNYGIMSYSL WIIAATWMWA PFFFNPSGLD WDKIIEDYND
WQNWLKTTND SADSWFGWWS NEQEYLEHTT RGARFVAGIR KLRFLLVAIG MYLNMMYNAY
FERPNRVITS DDDMLTYALS GLVVVIFVLL ICCGYIASRV TKKMSMKQRK LRKMKFLLSC
CCFLISMLSL TVLSVGNLFA IFILLFVAVY WFMQMCILRL QYHHIVVRAL ARAYDRAVGW
IVFGPIMIVS MFLPFISSFQ QRVMFNNAFT SGLEVSKLFA HDVAPAQVVK VKRVSKKKKN
RDD
//
