ID A0A329SR80_9STRA Unreviewed; 1137 AA.
AC A0A329SR80;
DT 10-OCT-2018, integrated into UniProtKB/TrEMBL.
DT 10-OCT-2018, sequence version 1.
DT 08-NOV-2023, entry version 15.
DE RecName: Full=MMS19 nucleotide excision repair protein {ECO:0000256|RuleBase:RU367072};
GN ORFNames=JG687_00011739 {ECO:0000313|EMBL:KAG6954574.1}, PC110_g4749
GN {ECO:0000313|EMBL:RAW39041.1}, PC113_g18142
GN {ECO:0000313|EMBL:KAG2845663.1}, PC115_g17624
GN {ECO:0000313|EMBL:KAG2896057.1}, PC117_g19382
GN {ECO:0000313|EMBL:KAG2910522.1}, PC118_g17844
GN {ECO:0000313|EMBL:KAG2968742.1}, PC129_g18835
GN {ECO:0000313|EMBL:KAG3210162.1};
OS Phytophthora cactorum.
OC Eukaryota; Sar; Stramenopiles; Oomycota; Peronosporales; Peronosporaceae;
OC Phytophthora.
OX NCBI_TaxID=29920 {ECO:0000313|EMBL:RAW39041.1, ECO:0000313|Proteomes:UP000251314};
RN [1] {ECO:0000313|EMBL:RAW39041.1, ECO:0000313|Proteomes:UP000251314}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=10300 {ECO:0000313|EMBL:RAW39041.1,
RC ECO:0000313|Proteomes:UP000251314};
RA Armitage A.D., Lysoe E., Nellist C.F., Harrison R.J., Brurberg M.B.;
RT "Draft genome of the strawberry crown rot pathogen Phytophthora cactorum.";
RL Submitted (JAN-2018) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:KAG2845663.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=15-7 {ECO:0000313|EMBL:KAG2845663.1}, 4032
RC {ECO:0000313|EMBL:KAG2896057.1}, 4040 {ECO:0000313|EMBL:KAG2910522.1},
RC P415 {ECO:0000313|EMBL:KAG2968742.1}, and P421
RC {ECO:0000313|EMBL:KAG3210162.1};
RA Armitage A.D., Nellist C.F., Bates H., Vickerstaff R.J., Harrison R.J.;
RT "Effector identification in a new, highly contiguous assembly of the
RT strawberry crown rot pathogen Phytophthora cactorum.";
RL Submitted (OCT-2018) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:KAG6954574.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=NZFS 3830 {ECO:0000313|EMBL:KAG6954574.1};
RA Mcdougal R., Panda P., Williams N., Studholme D.J.;
RT "Phytophthora aleatoria, a newly-described species from Pinus radiata is
RT distinct from Phytophthora cactorum isolates based on comparative
RT genomics.";
RL Submitted (JAN-2021) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Key component of the cytosolic iron-sulfur protein assembly
CC (CIA) complex, a multiprotein complex that mediates the incorporation
CC of iron-sulfur cluster into apoproteins specifically involved in DNA
CC metabolism and genomic integrity. In the CIA complex, MMS19 acts as an
CC adapter between early-acting CIA components and a subset of cellular
CC target iron-sulfur proteins. {ECO:0000256|RuleBase:RU367072}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|RuleBase:RU367072}.
CC -!- SIMILARITY: Belongs to the MET18/MMS19 family.
CC {ECO:0000256|ARBA:ARBA00009340, ECO:0000256|RuleBase:RU367072}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RAW39041.1}.
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DR EMBL; RCMG01000831; KAG2845663.1; -; Genomic_DNA.
DR EMBL; RCMI01000850; KAG2896057.1; -; Genomic_DNA.
DR EMBL; RCMK01000839; KAG2910522.1; -; Genomic_DNA.
DR EMBL; RCML01000839; KAG2968742.1; -; Genomic_DNA.
DR EMBL; RCMV01001137; KAG3210162.1; -; Genomic_DNA.
DR EMBL; JAENGZ010000736; KAG6954574.1; -; Genomic_DNA.
DR EMBL; MJFZ01000075; RAW39041.1; -; Genomic_DNA.
DR STRING; 29920.A0A329SR80; -.
DR Proteomes; UP000251314; Unassembled WGS sequence.
DR Proteomes; UP000688947; Unassembled WGS sequence.
DR Proteomes; UP000697107; Unassembled WGS sequence.
DR Proteomes; UP000735874; Unassembled WGS sequence.
DR Proteomes; UP000736787; Unassembled WGS sequence.
DR Proteomes; UP000760860; Unassembled WGS sequence.
DR Proteomes; UP000774804; Unassembled WGS sequence.
DR GO; GO:0097361; C:CIA complex; IEA:UniProtKB-UniRule.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0006281; P:DNA repair; IEA:UniProtKB-UniRule.
DR GO; GO:0016226; P:iron-sulfur cluster assembly; IEA:UniProtKB-UniRule.
DR GO; GO:0097428; P:protein maturation by iron-sulfur cluster transfer; IEA:UniProtKB-UniRule.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 2.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR039920; MET18/MMS19.
DR InterPro; IPR024687; MMS19_C.
DR InterPro; IPR029240; MMS19_N.
DR PANTHER; PTHR12891; DNA REPAIR/TRANSCRIPTION PROTEIN MET18/MMS19; 1.
DR PANTHER; PTHR12891:SF0; MMS19 NUCLEOTIDE EXCISION REPAIR PROTEIN HOMOLOG; 1.
DR Pfam; PF12460; MMS19_C; 1.
DR Pfam; PF14500; MMS19_N; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
PE 3: Inferred from homology;
KW DNA damage {ECO:0000256|RuleBase:RU367072};
KW DNA repair {ECO:0000256|RuleBase:RU367072};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|RuleBase:RU367072};
KW Reference proteome {ECO:0000313|Proteomes:UP000251314};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 46..336
FT /note="MMS19 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF14500"
FT DOMAIN 632..1094
FT /note="MMS19 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF12460"
SQ SEQUENCE 1137 AA; 123070 MW; BCFCF75EE213C929 CRC64;
MFSLDAPLAP AIDAFVDPEN DDAAQKTGLN TVVMQVHRQV SMEALIQALG AYLTNGDDKV
RSRATLLLAE VLTRLPELQL TPSAVQLLMT FFADRLADFP SASACLRALL ALETHHATQV
QSPRTTVALV LKLGKTLHIP QLGQAMRKMC FDLMQLALTQ STVVELLLDS VPASKDAQDA
SVDDAEQSED LGRHFAQTFL SSMEGEKDPR NLLLCMQVAR TLLSKLEPVF SRSDALLQQY
FDVVSCYFPI IFTPPPNDPY GITSEGLILS LRHAFAASDL LAPLVLPFLL KKLASTVVEA
KLDAIQTLVF CGERYSMNAL LLQMHAVANA LYDEVLDGEK QEVIAEARQA ISRFSGVVAR
AKAQDTPGAA YAWSKFVVDM TARAAGELRE NAADSMVSVS AGQVLAALGR ESSMSFAHVL
KIAVPLLVEQ LNNESSGVES VSSKCEAALA RILLLVDTID QEIDQSGQAQ PMRPHAPALI
DALVNFLSSD QDNQINPGSS PTARCVAVVA LCHLLTFPPS PIVAPAQVKA LINLFTRMLL
LDPAEEVRTA CLQSLKEIST VSAASVTSTS SGEHPVTGGY AAFVVEISLA RLMAAVNEGS
DHEDDDDEEG TGVAAVLAAS NRNFDSFFEE ALLAITELCR ESSIFQATIF LLIDLCVEKD
GGKQSAIGFC EAEGDVARQR HVDCILDAVA KIVEINAGDR TSMEFCVKAS SSASIIFRLL
TAVETSAARA TASSSDKSGL VDDVKLAACI RIFRAVMQNV SSATQQQLVD AVVPAFLRTN
PSEPASLQLV PLFAAVINSA ARDVTLPESS LVINRLLELA QSGATAVPEP SPRQLQLVYT
EAALSSAKSL ASIVNKMSDG AEFDALIDLL LSKKLAVVIS NPVETFTVRV AALQIYAWIA
KALVIRGHKV HAPVCLRFLC SFLTPDGDVN MEQEGDDQQA AALRMEVAKT FKLLVSEYPD
VLNRKCGAFI TFLYRQRLFD LVFPVLLEYI RAHIGEEASV AALVAFAQVI AHSPKAIYLP
HLAQIFPLMV QALNTDDREL GSAAIQTFKP LLLESVESAK PFLKDVFPGL LKQAQFGPAA
KDRHAALECL AKLATIPYEL VHPYKDIVLR KLLLVLDDRK RLVRHMAVRV RNQWSIL
//
