ID A0A329T267_9STRA Unreviewed; 914 AA.
AC A0A329T267;
DT 10-OCT-2018, integrated into UniProtKB/TrEMBL.
DT 10-OCT-2018, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE RecName: Full=Peptidase M12A domain-containing protein {ECO:0000259|PROSITE:PS51864};
GN ORFNames=PC110_g1132 {ECO:0000313|EMBL:RAW42734.1}, PC113_g2118
GN {ECO:0000313|EMBL:KAG2867310.1}, PC115_g1478
GN {ECO:0000313|EMBL:KAG2942380.1}, PC117_g2245
GN {ECO:0000313|EMBL:KAG2953164.1}, PC118_g1471
GN {ECO:0000313|EMBL:KAG2998138.1}, PC129_g10052
GN {ECO:0000313|EMBL:KAG3219172.1};
OS Phytophthora cactorum.
OC Eukaryota; Sar; Stramenopiles; Oomycota; Peronosporales; Peronosporaceae;
OC Phytophthora.
OX NCBI_TaxID=29920 {ECO:0000313|EMBL:RAW42734.1, ECO:0000313|Proteomes:UP000251314};
RN [1] {ECO:0000313|EMBL:RAW42734.1, ECO:0000313|Proteomes:UP000251314}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=10300 {ECO:0000313|EMBL:RAW42734.1,
RC ECO:0000313|Proteomes:UP000251314};
RA Armitage A.D., Lysoe E., Nellist C.F., Harrison R.J., Brurberg M.B.;
RT "Draft genome of the strawberry crown rot pathogen Phytophthora cactorum.";
RL Submitted (JAN-2018) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:KAG2867310.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=15-7 {ECO:0000313|EMBL:KAG2867310.1}, 4032
RC {ECO:0000313|EMBL:KAG2942380.1}, 4040 {ECO:0000313|EMBL:KAG2953164.1},
RC P415 {ECO:0000313|EMBL:KAG2998138.1}, and P421
RC {ECO:0000313|EMBL:KAG3219172.1};
RA Armitage A.D., Nellist C.F., Bates H., Vickerstaff R.J., Harrison R.J.;
RT "Effector identification in a new, highly contiguous assembly of the
RT strawberry crown rot pathogen Phytophthora cactorum.";
RL Submitted (OCT-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC Evidence={ECO:0000256|PROSITE-ProRule:PRU01211};
CC Note=Binds 1 zinc ion per subunit. {ECO:0000256|PROSITE-
CC ProRule:PRU01211};
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU01211}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RAW42734.1}.
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DR EMBL; RCMG01000027; KAG2867310.1; -; Genomic_DNA.
DR EMBL; RCMI01000018; KAG2942380.1; -; Genomic_DNA.
DR EMBL; RCMK01000028; KAG2953164.1; -; Genomic_DNA.
DR EMBL; RCML01000018; KAG2998138.1; -; Genomic_DNA.
DR EMBL; RCMV01000324; KAG3219172.1; -; Genomic_DNA.
DR EMBL; MJFZ01000012; RAW42734.1; -; Genomic_DNA.
DR STRING; 29920.A0A329T267; -.
DR Proteomes; UP000251314; Unassembled WGS sequence.
DR Proteomes; UP000697107; Unassembled WGS sequence.
DR Proteomes; UP000735874; Unassembled WGS sequence.
DR Proteomes; UP000736787; Unassembled WGS sequence.
DR Proteomes; UP000760860; Unassembled WGS sequence.
DR Proteomes; UP000774804; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:UniProtKB-UniRule.
DR GO; GO:0006508; P:proteolysis; IEA:InterPro.
DR Gene3D; 3.40.390.10; Collagenase (Catalytic Domain); 1.
DR InterPro; IPR024079; MetalloPept_cat_dom_sf.
DR InterPro; IPR001506; Peptidase_M12A.
DR InterPro; IPR006026; Peptidase_Metallo.
DR PANTHER; PTHR10127; DISCOIDIN, CUB, EGF, LAMININ , AND ZINC METALLOPROTEASE DOMAIN CONTAINING; 1.
DR PANTHER; PTHR10127:SF850; METALLOENDOPEPTIDASE; 1.
DR Pfam; PF01400; Astacin; 1.
DR SMART; SM00235; ZnMc; 1.
DR SUPFAM; SSF55486; Metalloproteases ('zincins'), catalytic domain; 1.
DR PROSITE; PS51864; ASTACIN; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Metal-binding {ECO:0000256|PROSITE-ProRule:PRU01211};
KW Reference proteome {ECO:0000313|Proteomes:UP000251314};
KW Signal {ECO:0000256|SAM:SignalP}; Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius};
KW Zinc {ECO:0000256|PROSITE-ProRule:PRU01211}.
FT SIGNAL 1..27
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 28..914
FT /note="Peptidase M12A domain-containing protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5039986130"
FT TRANSMEM 865..885
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 589..812
FT /note="Peptidase M12A"
FT /evidence="ECO:0000259|PROSITE:PS51864"
FT BINDING 686
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /ligand_note="catalytic"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01211"
FT BINDING 690
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /ligand_note="catalytic"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01211"
FT BINDING 696
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /ligand_note="catalytic"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01211"
SQ SEQUENCE 914 AA; 101614 MW; 5E1EE9C0BF3F97CA CRC64;
MVFCRLLSSV VCGLGLVTWS VLPSAQAAFY VCPDGCAAML LPRDMEMIDD CICDDGVDTT
AQEAAADAMD TGEFICKGRY KSKRGAPAPR SFADCDCYHP YEKDPKTLEC VLNGCPRAGN
YEPKPDVSQV ESLADCTCAA PFVKVETSGQ CVRGDGDKAP IRAFKCPPNS TPTPDIVPQS
FADCHCSWGF VRNSLEACER EFAAYVCPVN SVKRSDLPIG ERPRGFFDCE CLSTGDYQRD
EEVHACWPVS QMQARKAKRK HSNVRDTEVD EYADFEVVDR EATAYQCPPF SRAVATVPHS
IEQCQCIPGY AWKMPEMTCV RTSAYKCPEH AYKRSKLQGS EIETGFEDCA CARGYFLDAV
AQRCVPWMLA NSNACPPFAV LTQWPLQSNA NCKCVYGLNE TIYEEEDEAR RNAEDQEVVR
KRRKECNTRP VDSSRPDFSQ CPHDSMATTW PAESADGCTC LSGLEMTPLT EQEISRGVGD
GFHCVTTKEK KILADEAAAA CRAPGVIHSL SGECRLPIEE IPEKKTTDTK PEGVLFKGIE
YHYELVDDTI MVIQGDVAIG ERFVWDDVDP ADPEEVTTRI EHVLHGYYNS GRDHRWPHEK
ICFQVDKSAR SFLRTLLSAT EHITHATGFK FHRCTGDNCR TDMSCRSHDF VVVQGVESSC
YSFVGRIGGP QRLGVSADCG LGNVVHVLLH AVGLRHAVDR VDRDEHVRIA WECIPESKRS
YFVVEEMSPA PTPTRAKDHV LDPPPYDLFS IMHHPVDAFV HSDSDDTKPQ WCPSVVPLIA
DDDKRLAVMK DMGQRERMTT TDVKSVWALY PGLKKKHHDR QKAGESGEAQ AEDLHDSFLH
TDEDAVKTES AAGYGGQHRG FGQRLVSFLG AVVTLVGFGA MLAFITTELR RRALLSSGDD
YFYEAPLIDS KNDI
//
