ID A0A337RZK9_FELCA Unreviewed; 758 AA.
AC A0A337RZK9;
DT 10-OCT-2018, integrated into UniProtKB/TrEMBL.
DT 10-OCT-2018, sequence version 1.
DT 24-JAN-2024, entry version 20.
DE SubName: Full=SEC14 and spectrin domain containing 1 {ECO:0000313|Ensembl:ENSFCAP00000041613.1};
GN Name=SESTD1 {ECO:0000313|Ensembl:ENSFCAP00000041613.1,
GN ECO:0000313|VGNC:VGNC:65037};
OS Felis catus (Cat) (Felis silvestris catus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Feliformia; Felidae; Felinae; Felis.
OX NCBI_TaxID=9685 {ECO:0000313|Ensembl:ENSFCAP00000041613.1, ECO:0000313|Proteomes:UP000011712};
RN [1] {ECO:0000313|Ensembl:ENSFCAP00000041613.1, ECO:0000313|Proteomes:UP000011712}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Abyssinian {ECO:0000313|Ensembl:ENSFCAP00000041613.1,
RC ECO:0000313|Proteomes:UP000011712};
RX PubMed=17975172; DOI=10.1101/gr.6380007;
RA Pontius J.U., Mullikin J.C., Smith D.R., Lindblad-Toh K., Gnerre S.,
RA Clamp M., Chang J., Stephens R., Neelam B., Volfovsky N., Schaffer A.A.,
RA Agarwala R., Narfstrom K., Murphy W.J., Giger U., Roca A.L., Antunes A.,
RA Menotti-Raymond M., Yuhki N., Pecon-Slattery J., Johnson W.E., Bourque G.,
RA Tesler G., O'Brien S.J.;
RT "Initial sequence and comparative analysis of the cat genome.";
RL Genome Res. 17:1675-1689(2007).
RN [2] {ECO:0000313|Ensembl:ENSFCAP00000041613.1, ECO:0000313|Proteomes:UP000011712}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Abyssinian {ECO:0000313|Ensembl:ENSFCAP00000041613.1,
RC ECO:0000313|Proteomes:UP000011712};
RA Hillier L.W., Warren W., Obrien S., Wilson R.K.;
RT "Sequence assembly of the Felis catus genome version 6.2.";
RL Submitted (SEP-2011) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|Ensembl:ENSFCAP00000041613.1}
RP IDENTIFICATION.
RC STRAIN=breed Abyssinian {ECO:0000313|Ensembl:ENSFCAP00000041613.1};
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the SOLO family.
CC {ECO:0000256|ARBA:ARBA00038285}.
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DR EMBL; AANG04001482; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; A0A337RZK9; -.
DR STRING; 9685.ENSFCAP00000041613; -.
DR PaxDb; 9685-ENSFCAP00000016344; -.
DR Ensembl; ENSFCAT00000054673.2; ENSFCAP00000041613.1; ENSFCAG00000018813.5.
DR VGNC; VGNC:65037; SESTD1.
DR GeneTree; ENSGT00730000111148; -.
DR InParanoid; A0A337RZK9; -.
DR OMA; PDAFWDK; -.
DR Proteomes; UP000011712; Chromosome C1.
DR Bgee; ENSFCAG00000018813; Expressed in uterus and 10 other cell types or tissues.
DR GO; GO:0034704; C:calcium channel complex; IEA:Ensembl.
DR GO; GO:0045111; C:intermediate filament cytoskeleton; IEA:Ensembl.
DR GO; GO:0070300; F:phosphatidic acid binding; IEA:Ensembl.
DR GO; GO:0043325; F:phosphatidylinositol-3,4-bisphosphate binding; IBA:GO_Central.
DR GO; GO:0080025; F:phosphatidylinositol-3,5-bisphosphate binding; IBA:GO_Central.
DR GO; GO:0032266; F:phosphatidylinositol-3-phosphate binding; IBA:GO_Central.
DR GO; GO:0005546; F:phosphatidylinositol-4,5-bisphosphate binding; IBA:GO_Central.
DR GO; GO:0070273; F:phosphatidylinositol-4-phosphate binding; IBA:GO_Central.
DR GO; GO:0010314; F:phosphatidylinositol-5-phosphate binding; IBA:GO_Central.
DR GO; GO:1904878; P:negative regulation of calcium ion transmembrane transport via high voltage-gated calcium channel; IEA:Ensembl.
DR Gene3D; 1.20.58.60; -; 2.
DR InterPro; IPR001251; CRAL-TRIO_dom.
DR PANTHER; PTHR46607; SEC14 DOMAIN AND SPECTRIN REPEAT-CONTAINING PROTEIN 1; 1.
DR PANTHER; PTHR46607:SF1; SEC14 DOMAIN AND SPECTRIN REPEAT-CONTAINING PROTEIN 1; 1.
DR Pfam; PF13716; CRAL_TRIO_2; 1.
DR SUPFAM; SSF46966; Spectrin repeat; 1.
DR PROSITE; PS50191; CRAL_TRIO; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000011712};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 104..215
FT /note="CRAL-TRIO"
FT /evidence="ECO:0000259|PROSITE:PS50191"
FT REGION 1..86
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 40..61
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 758 AA; 85916 MW; BE4E2672B81A1830 CRC64;
MRGGRQAARA AAPCLTHGGA GTRFAASGWS RRRRRPGPLR PRPAFLPPRP PPPPAPSSRP
RVLPTNPGAA GRPRERQRQP GGKDRRSGLI LTIPLCLEQT NMDELSVTLD YLLSIPSEKC
KARGFTVIVD GRKSQWNVVK TVVLMLQNVV PAEVSLVCVV KPDEFWDKKV THFCFWKEKD
RLGFEVILVS ANKLTRYIEP CQLTEDFGGS LTYDHMDWLN KRLVFEKFTK ESTSLLDELA
LINNGSDKGS QQEKERSVDL NFLPSVDPET VLQTGHELLS ELQQRRFNGS DGGVSWSPMD
DELLAQPQVM KLLDSLREQY TRYQEVCRQR SKRTQLEEIQ QKVMQVVNWL EGPGSEQLRA
QWGIGDSIRA SQALQQKHEE IESQHSEWFA VYVELNQQIA ALLNAGDEED LVELKSLQQQ
LSDVCYRQAS QLEFRQNLLQ AALEFHGVAQ DLSQQLDGLL GMLCVDVAPA DGASIQQTLK
LLEEKLKSVD VGLQGLREKG QGLLDQISNQ ASLAYGKDVT IENKENVDHI QGVMEDMQLR
KQRCEDMVDV RRLKMLQMVQ LFKCEEDAAQ AVEWLSELLD ALLKTHIRLG DDAQETKVLL
EKHRKFVDVA QSTYDYGRQL LQATVVLCQS LRCTSRSSGD TLPRLNRVWK QFTIASEERV
HRLEMAIAFH SNAEKILQDC PEEPEAINDE EQFDEIEAVG KSLLDRLTVP VVYPDGTEQY
FGSPSDMAST AEHIRDRMKL VSLKRQQLRH PEMMTTES
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