ID A0A337S0G2_FELCA Unreviewed; 72 AA.
AC A0A337S0G2;
DT 10-OCT-2018, integrated into UniProtKB/TrEMBL.
DT 11-DEC-2019, sequence version 2.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=LITAF domain containing {ECO:0000313|Ensembl:ENSFCAP00000043475.2};
GN Name=LITAFD {ECO:0000313|Ensembl:ENSFCAP00000043475.2};
OS Felis catus (Cat) (Felis silvestris catus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Feliformia; Felidae; Felinae; Felis.
OX NCBI_TaxID=9685 {ECO:0000313|Ensembl:ENSFCAP00000043475.2, ECO:0000313|Proteomes:UP000011712};
RN [1] {ECO:0000313|Ensembl:ENSFCAP00000043475.2, ECO:0000313|Proteomes:UP000011712}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Abyssinian {ECO:0000313|Ensembl:ENSFCAP00000043475.2,
RC ECO:0000313|Proteomes:UP000011712};
RX PubMed=17975172; DOI=10.1101/gr.6380007;
RA Pontius J.U., Mullikin J.C., Smith D.R., Lindblad-Toh K., Gnerre S.,
RA Clamp M., Chang J., Stephens R., Neelam B., Volfovsky N., Schaffer A.A.,
RA Agarwala R., Narfstrom K., Murphy W.J., Giger U., Roca A.L., Antunes A.,
RA Menotti-Raymond M., Yuhki N., Pecon-Slattery J., Johnson W.E., Bourque G.,
RA Tesler G., O'Brien S.J.;
RT "Initial sequence and comparative analysis of the cat genome.";
RL Genome Res. 17:1675-1689(2007).
RN [2] {ECO:0000313|Ensembl:ENSFCAP00000043475.2, ECO:0000313|Proteomes:UP000011712}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Abyssinian {ECO:0000313|Ensembl:ENSFCAP00000043475.2,
RC ECO:0000313|Proteomes:UP000011712};
RA Hillier L.W., Warren W., Obrien S., Wilson R.K.;
RT "Sequence assembly of the Felis catus genome version 6.2.";
RL Submitted (SEP-2011) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|Ensembl:ENSFCAP00000043475.2}
RP IDENTIFICATION.
RC STRAIN=breed Abyssinian {ECO:0000313|Ensembl:ENSFCAP00000043475.2};
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Endosome membrane
CC {ECO:0000256|ARBA:ARBA00004125}; Peripheral membrane protein
CC {ECO:0000256|ARBA:ARBA00004125}; Cytoplasmic side
CC {ECO:0000256|ARBA:ARBA00004125}. Lysosome membrane
CC {ECO:0000256|ARBA:ARBA00004630}; Peripheral membrane protein
CC {ECO:0000256|ARBA:ARBA00004630}; Cytoplasmic side
CC {ECO:0000256|ARBA:ARBA00004630}.
CC -!- SIMILARITY: Belongs to the CDIP1/LITAF family.
CC {ECO:0000256|ARBA:ARBA00005975}.
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DR EMBL; AANG04001668; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; A0A337S0G2; -.
DR STRING; 9685.ENSFCAP00000043475; -.
DR Ensembl; ENSFCAT00000064599.2; ENSFCAP00000043475.2; ENSFCAG00000046455.2.
DR GeneTree; ENSGT00940000163474; -.
DR InParanoid; A0A337S0G2; -.
DR OMA; PYCGNYV; -.
DR Proteomes; UP000011712; Chromosome E3.
DR Bgee; ENSFCAG00000046455; Expressed in testis and 2 other cell types or tissues.
DR GO; GO:0098560; C:cytoplasmic side of late endosome membrane; IBA:GO_Central.
DR GO; GO:0098574; C:cytoplasmic side of lysosomal membrane; IBA:GO_Central.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0008270; F:zinc ion binding; IBA:GO_Central.
DR GO; GO:0001817; P:regulation of cytokine production; IBA:GO_Central.
DR InterPro; IPR006629; LITAF.
DR InterPro; IPR037519; LITAF_fam.
DR PANTHER; PTHR23292; LIPOPOLYSACCHARIDE-INDUCED TUMOR NECROSIS FACTOR-ALPHA FACTOR; 1.
DR PANTHER; PTHR23292:SF45; LITAF DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF10601; zf-LITAF-like; 1.
DR SMART; SM00714; LITAF; 1.
DR PROSITE; PS51837; LITAF; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000011712};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius};
KW Zinc {ECO:0000256|ARBA:ARBA00022833}.
FT TRANSMEM 24..47
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 1..71
FT /note="LITAF"
FT /evidence="ECO:0000259|PROSITE:PS51837"
SQ SEQUENCE 72 AA; 8143 MW; 93DFB16C997793A2 CRC64;
IPVQSICHYC GNRIITVTTP VPGVLTWLLC TGLFVFGCFL GCCFLPFCMD SLMDVKHTCP
VCHQELFCYH RL
//
