ID A0A337SE21_FELCA Unreviewed; 1018 AA.
AC A0A337SE21;
DT 10-OCT-2018, integrated into UniProtKB/TrEMBL.
DT 10-OCT-2018, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=Cytoplasmic polyadenylation element binding protein 2 {ECO:0000313|Ensembl:ENSFCAP00000048761.1};
GN Name=CPEB2 {ECO:0000313|Ensembl:ENSFCAP00000048761.1,
GN ECO:0000313|VGNC:VGNC:78474};
OS Felis catus (Cat) (Felis silvestris catus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Feliformia; Felidae; Felinae; Felis.
OX NCBI_TaxID=9685 {ECO:0000313|Ensembl:ENSFCAP00000048761.1, ECO:0000313|Proteomes:UP000011712};
RN [1] {ECO:0000313|Ensembl:ENSFCAP00000048761.1, ECO:0000313|Proteomes:UP000011712}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Abyssinian {ECO:0000313|Ensembl:ENSFCAP00000048761.1,
RC ECO:0000313|Proteomes:UP000011712};
RX PubMed=17975172; DOI=10.1101/gr.6380007;
RA Pontius J.U., Mullikin J.C., Smith D.R., Lindblad-Toh K., Gnerre S.,
RA Clamp M., Chang J., Stephens R., Neelam B., Volfovsky N., Schaffer A.A.,
RA Agarwala R., Narfstrom K., Murphy W.J., Giger U., Roca A.L., Antunes A.,
RA Menotti-Raymond M., Yuhki N., Pecon-Slattery J., Johnson W.E., Bourque G.,
RA Tesler G., O'Brien S.J.;
RT "Initial sequence and comparative analysis of the cat genome.";
RL Genome Res. 17:1675-1689(2007).
RN [2] {ECO:0000313|Ensembl:ENSFCAP00000048761.1, ECO:0000313|Proteomes:UP000011712}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Abyssinian {ECO:0000313|Ensembl:ENSFCAP00000048761.1,
RC ECO:0000313|Proteomes:UP000011712};
RA Hillier L.W., Warren W., Obrien S., Wilson R.K.;
RT "Sequence assembly of the Felis catus genome version 6.2.";
RL Submitted (SEP-2011) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|Ensembl:ENSFCAP00000048761.1}
RP IDENTIFICATION.
RC STRAIN=breed Abyssinian {ECO:0000313|Ensembl:ENSFCAP00000048761.1};
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the RRM CPEB family.
CC {ECO:0000256|ARBA:ARBA00010347}.
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DR EMBL; AANG04001605; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; A0A337SE21; -.
DR Ensembl; ENSFCAT00000065823.1; ENSFCAP00000048761.1; ENSFCAG00000027193.4.
DR VGNC; VGNC:78474; CPEB2.
DR GeneTree; ENSGT00940000160357; -.
DR Proteomes; UP000011712; Chromosome B1.
DR Bgee; ENSFCAG00000027193; Expressed in testis and 11 other cell types or tissues.
DR GO; GO:0003730; F:mRNA 3'-UTR binding; IEA:InterPro.
DR GO; GO:0045182; F:translation regulator activity; IEA:InterPro.
DR CDD; cd19757; Bbox1; 1.
DR CDD; cd12724; RRM1_CPEB2_like; 1.
DR CDD; cd12726; RRM2_CPEB2_like; 1.
DR Gene3D; 3.30.70.330; -; 2.
DR Gene3D; 4.10.640.40; Cytoplasmic polyadenylation element-binding protein, ZZ domain; 1.
DR InterPro; IPR032296; CEBP_ZZ.
DR InterPro; IPR038446; CEBP_ZZ_sf.
DR InterPro; IPR034819; CPEB.
DR InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR InterPro; IPR035979; RBD_domain_sf.
DR InterPro; IPR000504; RRM_dom.
DR PANTHER; PTHR12566; CYTOPLASMIC POLYADENYLATION ELEMENT BINDING PROTEIN CPEB; 1.
DR PANTHER; PTHR12566:SF8; CYTOPLASMIC POLYADENYLATION ELEMENT-BINDING PROTEIN 2; 1.
DR Pfam; PF16366; CEBP_ZZ; 1.
DR Pfam; PF16367; RRM_7; 1.
DR SMART; SM00360; RRM; 2.
DR SUPFAM; SSF54928; RNA-binding domain, RBD; 1.
DR PROSITE; PS50102; RRM; 2.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000011712};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884, ECO:0000256|PROSITE-
KW ProRule:PRU00176}.
FT DOMAIN 761..848
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT DOMAIN 869..947
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT REGION 34..55
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 120..150
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 170..472
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 493..551
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 566..604
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 170..184
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 192..222
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 224..246
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 249..274
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 305..319
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 390..424
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 505..532
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 533..551
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 566..585
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1018 AA; 107718 MW; 0B4E13A4E6FC8B57 CRC64;
MRDFGFGVLQ TAPLRSSSPG SLFGSGAYRP YATGPTAAAA PLPSTTPFGP LSPPPLPVTG
FSEAASPFSI PLGCGGAGSS AAAASSSSPF LAHQQTMQDE LLLGLTQQPA RPLSGAAAAE
KLPNHHPGGG TNAGVTHLLP SQDFKPSLHH PSSSSASSCC CCRTSSPQDF SKRQQQQLSS
QKRKEFSPPH LPHPPDSKPP PPPPPLHCPG RFSPPPPGPL LQPAQLAQRQ QPQQPPQQQQ
FSVPHPQHLP PQDFAPRQRP ADLPPLPQLQ PSPPAAPRRR HGGAGSPRKT PAAGEGSAAE
PPNAGLAPST PPVNPAPGSM ESPNHPLLNS PSNLLPGGAL GAGAFSSLQS PDLPHPGGGG
GGGPPGGGGG GGSASPPPLP GFGTPWSVQT ASPPPQPQPQ PPPPPQQQQP PPPQQPPQPQ
PQQPGSSAAT PGGGGGGGGG GSLSAMPPPS PDSENGFYPG LPSSMNPAFF PSFSPVSPHG
CAGLSVPASG GGGGGGGGFG GPFSAAAVPP PPPPAMNLPQ QQPPPPAAPQ QPQSRRSPVS
PQLQQQHQAA AAAFLQQRNS YNHHQPLLKQ SPWSNHQSSG WGTGSVSWGA MHGRDHRRTG
NMGIPGTMNQ ISPLKKPFSG NVIAPPKFTR STPSLTPKSW IEDNVFRTDN NSNTLLPLQV
RMDRSRMYDS LNMHSLENSL IDIMRAEHDP LKGRLSYPHP GTDNLLMLNA RSYGRRRGRS
SLFPIDDGLL DDGHNDQVGV LNSPTCYSAH QNGERIERFS RKVFVGGLPP DIDEDEITAS
FRRFGPLVVD WPHKAESKSY FPPKGYAFLL FQEESSVQAL IDACIEEDGK LYLCVSSPTI
KDKPVQIRPW NLSDSDFVMD GSQPLDPRKT IFVGGVPRPL RAVELAMIMD RLYGGVCYAG
IDTDPELKYP KGAGRVAFSN QQSYIAAISA RFVQLQHGDI DKRVEVKPYV LDDQMCDECQ
GARCGGKFAP FFCANVTCLQ YYCEFCWANI HSRAGREFHK PLVKEGADRP RQIHFRWN
//
